{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:36:43Z","timestamp":1791542203855,"version":"4.3.4"},"reference-count":29,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Health and Welfare, Republic of Korea","award":["RS-2023-00302193"],"award-info":[{"award-number":["RS-2023-00302193"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: A new, purely refractive extended depth-of-focus (EDOF) intraocular lens (IOL) was designed with a continuous change in power to bridge the gap between monofocal and multifocal IOLs. This study aimed to evaluate the real-world clinical outcomes of the new EDOF IOL compared with those of the enhanced monofocal IOL. Methods: A retrospective analysis was conducted on 100 eyes from 50 patients undergoing bilateral cataract surgery with either the PureSee\u2122 EDOF (ZEN00V) or Eyhance\u2122 (ICB00) monofocal IOL at a single institution. Visual acuity, defocus curves, contrast sensitivity, and patient-reported outcomes were evaluated three months postoperatively. Results: The ZEN00V group demonstrated superior uncorrected intermediate (0.11 \u00b1 0.08 vs. 0.17 \u00b1 0.11 logMAR, p = 0.006) and near visual acuity (0.25 \u00b1 0.08 vs. 0.31 \u00b1 0.13 logMAR, p = 0.023) compared to the ICB00 group, with comparable distance visual acuity. Both groups exhibited comparable defocus curves and contrast sensitivity. While photic phenomena were more frequent in the ZEN00V group, spectacle dependence was significantly lower for near vision (36% vs. 80%, p = 0.002) and comparable for intermediate and far vision. Conclusions: The PureSee\u2122 EDOF IOL demonstrated enhanced intermediate and near vision with minimal compromise to distance vision while maintaining high contrast sensitivity. It also offered significant spectacle independence and patient satisfaction, making it a promising option for presbyopia correction.<\/jats:p>","DOI":"10.3390\/jcm14144967","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T10:55:41Z","timestamp":1752490541000},"page":"4967","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparative Outcomes of the Next-Generation Extended Depth-of-Focus Intraocular Lens and Enhanced Monofocal Intraocular Lens in Cataract Surgery"],"prefix":"10.3390","volume":"14","author":[{"given":"Do Young","family":"Kim","sequence":"first","affiliation":[{"name":"Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella Seo Yeon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2364-1318","authenticated-orcid":false,"given":"Hyunjin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Yi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Refractive Surgery, B&VIIT Eye Center, Seoul 06615, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2160-1679","authenticated-orcid":false,"given":"Ikhyun","family":"Jun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9855-1980","authenticated-orcid":false,"given":"Kyoung Yul","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7456-1749","authenticated-orcid":false,"given":"Ahmed","family":"Elsheikh","sequence":"additional","affiliation":[{"name":"School of Engineering, University of Liverpool, Liverpool L69 7ZX, UK"},{"name":"Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing 100191, China"},{"name":"National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London EC1V 2PD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-3842","authenticated-orcid":false,"given":"Tae-im","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"},{"name":"Department of Ophthalmology, Corneal Dystrophy Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"},{"name":"Department of Material Science and Engineering, Yonsei University, Seoul 03722, Republic of Korea"},{"name":"Affilate Faculty, Material Research Center for Batteries, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0886-3350(02)02011-4","article-title":"Intraocular lens power accuracy: How are we doing?","volume":"29","author":"Mamalis","year":"2003","journal-title":"J. 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