{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T16:49:15Z","timestamp":1785343755525,"version":"3.55.0"},"reference-count":90,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Heart failure (HF) is a complex clinical syndrome that results from any structural or functional impairment of ventricular filling or ejection of blood. The etiology of heart failure is multifactorial, encompassing ischemic heart disease, hypertension, valvular disorders, cardiomyopathies, and metabolic and infiltrative diseases. Despite advances in pharmacologic and device-based therapies, heart failure continues to carry a substantial burden of morbidity, mortality, and healthcare utilization. With the advancement and increased accessibility of cardiac imaging modalities, the diagnostic accuracy for identifying the underlying etiologies of nonischemic cardiomyopathy has significantly improved, allowing for more precise classification and tailored management strategies. This review aims to provide a comprehensive analysis of the current understanding of heart failure, encompassing epidemiology, etiological factors, with a specific focus on diagnostic imaging modalities including the role of echocardiography and strain imaging, cardiac magnetic resonance imaging (CMR), cardiac computed tomography (CT), and nuclear positron emission tomography (PET) imaging and recent advances in the diagnosis and management of heart failure.<\/jats:p>","DOI":"10.3390\/jcm14145002","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T11:52:58Z","timestamp":1752580378000},"page":"5002","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Cardiac Imaging in the Diagnosis and Management of Heart Failure"],"prefix":"10.3390","volume":"14","author":[{"given":"Mayuresh","family":"Chaudhari","sequence":"first","affiliation":[{"name":"UT Health Sciences Centre, Glen Biggs Institute, San Antonio, TX 78240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahi Lakshmi","family":"Ashwath","sequence":"additional","affiliation":[{"name":"UHS\/UT Heart and Vascular Institute, San Antonio, TX 78240, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.cardfail.2021.01.022","article-title":"Universal definition and classification of heart failure: A report of the Heart Failure Society of America, Heart Failure Association of the ESC, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure","volume":"27","author":"Bozkurt","year":"2021","journal-title":"J. Card. Fail."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart disease and stroke statistics\u20142021 update: A report from the American Heart Association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.15420\/cfr.2016:25:2","article-title":"Global public health burden of heart failure","volume":"3","author":"Savarese","year":"2017","journal-title":"Card. Fail. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(17)32520-5","article-title":"Temporal trends and patterns in heart failure incidence: A population-based study of 4 million individuals","volume":"391","author":"Conrad","year":"2018","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1016\/j.jacc.2013.05.019","article-title":"2013 ACCF\/AHA guideline for the management of heart failure","volume":"62","author":"Yancy","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1001\/jama.1996.03530440037034","article-title":"The progression from hypertension to congestive heart failure","volume":"275","author":"Levy","year":"1996","journal-title":"JAMA"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: A population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/CIRCULATIONAHA.106.174287","article-title":"Contemporary definitions and classification of the cardiomyopathies","volume":"113","author":"Maron","year":"2006","journal-title":"Circulation"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1161\/CIRCULATIONAHA.105.584532","article-title":"Myocarditis: Current trends in diagnosis and treatment","volume":"113","author":"Magnani","year":"2006","journal-title":"Circulation"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.2337\/diacare.26.8.2433","article-title":"Heart failure: The frequent, forgotten, and often fatal complication of diabetes","volume":"26","author":"Bell","year":"2003","journal-title":"Diabetes Care"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1161\/CIRCULATIONAHA.106.678326","article-title":"Thyroid disease and the heart","volume":"116","author":"Klein","year":"2007","journal-title":"Circulation"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1056\/NEJM198902163200701","article-title":"The effects of alcoholism on skeletal and cardiac muscle","volume":"320","author":"Estruch","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1161\/01.CIR.0000133187.74800.B9","article-title":"Cardiovascular complications of cancer therapy: Diagnosis, pathogenesis, and management","volume":"109","author":"Yeh","year":"2004","journal-title":"Circulation"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nrcardio.2013.105","article-title":"Dilated cardiomyopathy: The complexity of a diverse genetic architecture","volume":"10","author":"Hershberger","year":"2013","journal-title":"Nat. Rev. Cardiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.jacc.2016.06.053","article-title":"AL (Light-chain) cardiac amyloidosis: A review of diagnosis and therapy","volume":"68","author":"Falk","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jacc.2016.03.605","article-title":"Cardiac sarcoidosis","volume":"68","author":"Birnie","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/eurjhf\/hfq120","article-title":"Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: A position statement","volume":"12","author":"Sliwa","year":"2010","journal-title":"Eur. J. Heart Fail."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1161\/CIRCULATIONAHA.113.008396","article-title":"Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010","volume":"130","author":"Marelli","year":"2014","journal-title":"Circulation"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2D","DOI":"10.1016\/S0002-9149(02)03373-8","article-title":"Atrial fibrillation in heart failure: Epidemiology, pathophysiology, and rationale for therapy","volume":"91","author":"Maisel","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"ref_20","unstructured":"Mann, D.L., Zipes, D.P., Libby, P., and Bonow, R.O. (2018). Nutritional deficiencies and heart failure. Braunwald\u2019s Heart Disease: A Textbook of Cardiovascular Medicine, Elsevier. [11th ed.]."},{"key":"ref_21","first-page":"e895","article-title":"ACC\/AHA Joint Committee Members. 2022 AHA\/ACC\/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012","volume":"33","author":"McMurray","year":"2012","journal-title":"Eur. Heart J."},{"key":"ref_23","first-page":"1828","article-title":"Natriuretic peptide testing for heart failure","volume":"134","author":"Januzzi","year":"2016","journal-title":"Circulation"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jacc.2012.03.057","article-title":"Breathing not properly 10 years later: What we have learned and what we still need to learn","volume":"60","author":"Maisel","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.ahj.2009.06.018","article-title":"Biomarker-guided therapy in chronic heart failure: A meta-analysis of randomized controlled trials","volume":"158","author":"Felker","year":"2009","journal-title":"Am. Heart J."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for cardiac chamber quantification by echocardiography","volume":"16","author":"Lang","year":"2015","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur. Heart J."},{"key":"ref_28","first-page":"602","article-title":"Acute heart failure risk stratification: Novel approaches and challenges","volume":"31","author":"Collins","year":"2013","journal-title":"Am. J. Emerg. Med."},{"key":"ref_29","first-page":"VI55","article-title":"The role of electrophysiologic testing in patients with congestive heart failure","volume":"87","author":"Stevenson","year":"1993","journal-title":"Circulation"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1161\/01.CIR.0000152819.97857.9D","article-title":"Cardiovascular magnetic resonance in cardiac amyloidosis","volume":"111","author":"Maceira","year":"2005","journal-title":"Circulation"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1161\/CIRCULATIONAHA.108.845792","article-title":"The progression of hypertensive heart disease","volume":"123","author":"Drazner","year":"2011","journal-title":"Circulation"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.echo.2008.11.023","article-title":"Recommendations for the evaluation of left ventricular diastolic function by echocardiography","volume":"22","author":"Nagueh","year":"2009","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.jacc.2017.04.025","article-title":"2017 ACC\/AHA\/HFSA Focused Update on New Pharmacological Therapy for Heart Failure","volume":"70","author":"Yancy","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.echo.2012.10.008","article-title":"Normal ranges of left ventricular strain: A meta-analysis","volume":"26","author":"Yingchoncharoen","year":"2013","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e000630","DOI":"10.1136\/openhrt-2017-000630","article-title":"Left ventricular longitudinal systolic function analysed by 2D speckle-tracking echocardiography in heart failure with preserved ejection fraction: A meta-analysis","volume":"4","author":"Morris","year":"2017","journal-title":"Open Heart."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.echo.2016.01.011","article-title":"Recommendations for the evaluation of left ventricular diastolic function by echocardiography","volume":"29","author":"Nagueh","year":"2016","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jcmg.2016.08.014","article-title":"LA strain for categorization of LV diastolic dysfunction","volume":"10","author":"Singh","year":"2017","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_39","first-page":"71","article-title":"The role of echocardiography in heart failure with preserved ejection fraction: Diagnosis, phenotyping, and monitoring","volume":"21","author":"Reddy","year":"2019","journal-title":"Curr. Cardiol. Rep."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1093\/eurheartj\/ehz641","article-title":"How to diagnose HFpEF: The HFA-PEFF diagnostic algorithm","volume":"40","author":"Pieske","year":"2019","journal-title":"Eur. Heart J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/ehf2.12159","article-title":"Left ventricular global longitudinal strain in patients with heart failure with preserved ejection fraction: Outcomes following an acute heart failure hospitalization","volume":"4","author":"Buggey","year":"2017","journal-title":"ESC Heart Fail."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1016\/j.jacc.2014.01.073","article-title":"Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy","volume":"63","author":"Thavendiranathan","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1136\/heartjnl-2012-302353","article-title":"Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis","volume":"98","author":"Phelan","year":"2012","journal-title":"Heart"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.echo.2014.07.012","article-title":"Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: A report from ASE and EACVI","volume":"27","author":"Plana","year":"2014","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.1093\/eurheartj\/ehac244","article-title":"2022 ESC Guidelines on cardio-oncology","volume":"43","author":"Lyon","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1093\/eurheartj\/ehw211","article-title":"2016 ESC position paper on cancer treatments and cardiovascular toxicity","volume":"37","author":"Zamorano","year":"2016","journal-title":"Eur. Heart J."},{"key":"ref_47","first-page":"493","article-title":"Reference values for right ventricular strain in healthy subjects: A meta-analysis","volume":"28","author":"Fine","year":"2015","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","article-title":"Guidelines for echocardiographic assessment of the right heart","volume":"23","author":"Rudski","year":"2010","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jacc.2019.02.027","article-title":"2019 ACC\/AHA\/ASE Key Data Elements and Definitions for Transthoracic Echocardiography: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Transthoracic Echocardiography) and the American Society of Echocardiography","volume":"74","author":"Douglas","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","article-title":"2022 ESC\/ERS Guidelines for pulmonary hypertension","volume":"43","author":"Humbert","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_51","first-page":"231","article-title":"RV strain as a predictor of mortality in PAH","volume":"61","author":"Fine","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_52","first-page":"348","article-title":"Right ventricular assessment in pulmonary hypertension","volume":"29","author":"Labrada","year":"2023","journal-title":"Curr. Opin. Pulm. Med."},{"key":"ref_53","first-page":"693","article-title":"Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure","volume":"40","author":"Grothues","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1056\/NEJM200011163432003","article-title":"The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction","volume":"343","author":"Kim","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"365404","DOI":"10.1155\/2014\/365404","article-title":"Role of cardiac magnetic resonance in the evaluation of dilated cardiomyopathy: Diagnostic contribution and prognostic significance","volume":"2014","author":"Francone","year":"2014","journal-title":"ISRN Radiol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1016\/j.jacc.2018.03.536","article-title":"Myocardial edema and prognosis in amyloidosis","volume":"71","author":"Kotecha","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.jacc.2020.12.024","article-title":"Cardiac Involvement in Fabry Disease: JACC Review Topic of the Week","volume":"77","author":"Pieroni","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/10976640600572889","article-title":"Reference right ventricular systolic and diastolic function normalized to age, gender, and body surface area","volume":"8","author":"Maceira","year":"2006","journal-title":"J. Cardiovasc. Magn. Reson."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.jacc.2009.02.007","article-title":"Cardiovascular magnetic resonance in myocarditis: A JACC White Paper","volume":"53","author":"Friedrich","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.echo.2013.07.002","article-title":"Reproducibility of speckle-tracking-based strain measures of left ventricular function in a community-based study","volume":"26","author":"Cheng","year":"2013","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1007\/s10741-024-10435-5","article-title":"Peripartum cardiomyopathy: A comprehensive and contemporary review","volume":"29","author":"Sigauke","year":"2024","journal-title":"Heart Fail Rev."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"e222552","DOI":"10.1148\/radiol.222552","article-title":"Cardiac MRI to Predict Sudden Cardiac Death Risk in Dilated Cardiomyopathy","volume":"307","author":"Li","year":"2023","journal-title":"Radiology"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12968-016-0308-4","article-title":"Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: A comprehensive review","volume":"18","author":"Haaf","year":"2016","journal-title":"J. Cardiovasc. Magn. Reson."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"e13815","DOI":"10.1111\/eci.13815","article-title":"Global longitudinal strain by CMR improves prognostic stratification in acute myocarditis presenting with normal LVEF","volume":"52","author":"Porcari","year":"2022","journal-title":"Eur. J. Clin. Invest."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1016\/j.jacc.2008.07.031","article-title":"Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis","volume":"52","author":"Budoff","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.jacc.2008.08.058","article-title":"Diagnostic accuracy of 64-slice CT coronary angiography: A prospective, multicenter, multivendor study","volume":"52","author":"Meijboom","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcct.2018.11.008","article-title":"Computed tomography imaging in the context of transcatheter aortic valve implantation (TAVI)\/transcatheter aortic valve replacement (TAVR)","volume":"13","author":"Blanke","year":"2019","journal-title":"J. Cardiovasc. Comput. Tomogr."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s12410-009-0052-3","article-title":"Value of Cardiac CT in Patients with Heart Failure","volume":"2","author":"Mangalat","year":"2009","journal-title":"Curr. Cardiovasc. Imaging Rep."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1148\/radiol.13121059","article-title":"Pericardial disease: Value of CT and MR imaging","volume":"267","author":"Bogaert","year":"2013","journal-title":"Radiology"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/tcmj.tcmj_125_24","article-title":"Cardiac computed tomography: Current practice, guidelines, applications, and prospects","volume":"37","author":"Shih","year":"2025","journal-title":"Tzu Chi Med. J."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1016\/S0735-1097(02)02489-0","article-title":"Positron emission tomography and recovery following revascularization (PARR-1): The importance of scar and the development of a prediction rule for the degree of recovery of left ventricular function","volume":"40","author":"Beanlands","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0735-1097(02)01726-6","article-title":"Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A meta-analysis","volume":"39","author":"Allman","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2967\/jnumed.111.090662","article-title":"The use of 18F-FDG PET in the diagnosis of cardiac sarcoidosis: A systematic review and metaanalysis including the Ontario experience","volume":"53","author":"Youssef","year":"2012","journal-title":"J. Nucl. Med."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1161\/CIRCULATIONAHA.116.021612","article-title":"Nonbiopsy diagnosis of cardiac transthyretin amyloidosis","volume":"133","author":"Gillmore","year":"2016","journal-title":"Circulation"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1016\/j.jacc.2018.09.042","article-title":"Coronary microvascular disease pathogenic mechanisms and therapeutic options: JACC state-of-the-art review","volume":"72","author":"Taqueti","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2009.02.065","article-title":"Cardiac positron emission tomography","volume":"54","author":"Bengel","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.jcmg.2024.07.011","article-title":"Myocardial Strain Imaging: Theory, Current Practice, and the Future","volume":"18","author":"Smiseth","year":"2025","journal-title":"J. Am. Coll. Cardiol. Img."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jcmg.2015.12.001","article-title":"T1-mapping and outcome in nonischemic cardiomyopathy","volume":"9","author":"Puntmann","year":"2016","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1016\/j.jacc.2018.07.043","article-title":"Coronary CT angiographic and flow reserve-guided management of patients with stable ischemic heart disease","volume":"72","author":"Terkelsen","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ejmp.2020.10.030","article-title":"Photon-counting CT review","volume":"79","author":"Flohr","year":"2020","journal-title":"Phys. Med."},{"key":"ref_81","first-page":"320","article-title":"Molecular imaging of myocardial inflammation with PET","volume":"25","author":"Thackeray","year":"2018","journal-title":"J. Nucl. Cardiol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.hfc.2025.01.002","article-title":"Coronary Microvascular Dysfunction: Identification, Special Populations, and Management Strategies","volume":"21","year":"2025","journal-title":"Heart Fail Clin."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1161\/CIRCULATIONAHA.118.034338","article-title":"Fully automated echocardiogram interpretation in clinical practice","volume":"138","author":"Zhang","year":"2018","journal-title":"Circulation"},{"key":"ref_84","unstructured":"Naghavi, M., Reeves, A., Budoff, M., Li, D., Atlas, K., Zhang, C., Atlas, T., Henschke, C., Defilippi, C., and Levy, D. (2024). Artificial intelligence analysis of coronary artery calcium scans predicts incident heart failure: MESA study. medRxiv."},{"key":"ref_85","unstructured":"Yan, Y., Chang, M., and Rajpurkar, P. (2024). echoGAN: A generative adversarial network for expanding echocardiogram field of view. arXiv."},{"key":"ref_86","first-page":"102558","article-title":"Artificial Intelligence in Cardiovascular Imaging and Interventional Cardiology: Emerging Trends and Clinical Implications","volume":"4","author":"Alsharqi","year":"2025","journal-title":"J. Soc. Cardiovasc. Angiogr. Interv."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Cau, R., Pisu, F., Suri, J.S., Montisci, R., Gatti, M., Mannelli, L., Gong, X., and Saba, L. (2024). Artificial Intelligence in the Differential Diagnosis of Cardiomyopathy Phenotypes. Diagnostics, 14.","DOI":"10.3390\/diagnostics14020156"},{"key":"ref_88","unstructured":"Chen, Z., Liu, Y., Yang, C., and He, J. (2024). Heart failure risk assessment through multi-modal large language models. arXiv."},{"key":"ref_89","first-page":"661","article-title":"PET\/MRI early after myocardial infarction: Evaluation of viability with late gadolinium enhancement transmurality vs. 18F-FDG uptake","volume":"16","author":"Rischpler","year":"2015","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"D\u2019Amato, A., Prosperi, S., Severino, P., Myftari, V., Labbro Francia, A., Cesti\u00e8, C., Pierucci, N., Marek-Iannucci, S., Mariani, M.V., and German\u00f2, R. (2024). Current Approaches to Worsening Heart Failure: Pathophysiological and Molecular Insights. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25031574"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/14\/5002\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:09:58Z","timestamp":1760033398000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/14\/5002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":90,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["jcm14145002"],"URL":"https:\/\/doi.org\/10.3390\/jcm14145002","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,15]]}}}