{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:58:53Z","timestamp":1790848733891,"version":"4.1.0"},"reference-count":47,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Research on sex differences in personality disorders profiles among individuals with Alcohol Use Disorder (AUD) remains limited. This study aimed to examine sex differences in personality disorders in AUD individuals attending to an outpatient alcohol and drugs treatment unit. Methods: Persons seeking alcohol detoxification treatment were assessed with the Millon Clinical Multiaxial Inventory-III (MCMI-III) after abstinence. Both dimensional trait scores and cluster personality disorders types distribution were analyzed. A total of 216 subjects, 114 women (53%) and 102 men (47%), participated in the study. Results: No sex differences were found for paranoid, schizoid or schizotypal traits scores of Cluster A types. Women exhibited higher scores on the Cluster B histrionic trait (48 \u00b1 22 vs. 39 \u00b1 23, p = 0.012), with no differences in antisocial, borderline, or narcissistic trait scores. Narcissistic personality disorder was more prevalent in men than women (44% vs. 20%, p = 0.012). Cluster C dependent (52 \u00b1 24 vs. 46 \u00b1 20, p = 0.025) and obsessive-compulsive (54 \u00b1 20 vs. 43 \u00b1 19, p = 0.012) traits scores were elevated in women, but only dependent personality disorder prevalence differed categorically (38% women vs. 15% men, p = 0.012). Conclusions: Employing both dimensional and cluster approaches enriches personality disorder research in AUD. Dependent personality disorder in Cluster C robustly differentiates sexes, while personality disorder patterns in Clusters A and B show minimal sex differences when both approaches are considered.<\/jats:p>","DOI":"10.3390\/jcm14145062","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T11:25:17Z","timestamp":1752751517000},"page":"5062","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Personality Patterns in Alcohol Use Disorder: A Study Focused on Sex Differences"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7663-1154","authenticated-orcid":false,"given":"Armando L.","family":"Morera-Fumero","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Dermatology and Psychiatry, Faculty of Medicine, University of La Laguna, 38200 Santa Cruz de Tenerife, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Natividad","family":"Garc\u00eda-G\u00f3mez","sequence":"additional","affiliation":[{"name":"San Miguel Addiction Association, 38006 Santa Cruz de Tenerife, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8732-2616","authenticated-orcid":false,"given":"Alejandro","family":"Jim\u00e9nez-Sosa","sequence":"additional","affiliation":[{"name":"Research Unit, University Hospital Complex of the Canary Islands, 38320 Santa Cruz de Tenerife, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"517","DOI":"10.4103\/IJPSYM.IJPSYM_164_18","article-title":"Comorbidity of Personality Disorder Among Substance Use Disorder Patients: A Narrative Review","volume":"40","author":"Parmar","year":"2018","journal-title":"Indian J. 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