{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:44:50Z","timestamp":1782913490105,"version":"3.54.5"},"reference-count":89,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Bcakground: The deepithelialized free gingival graft (DGG) technique provides high-quality connective tissue grafts (CTGs) with predictable outcomes for recession coverage. This study evaluates a novel method of free gingival graft (FGG) deepithelialization using an Er,Cr:YSGG laser (LDEE) for treating multiple gingival recessions. Methods: A split-mouth study was conducted on 46 (n = 46) recessions in nine patients (23 per test and control group). Sites were randomized. Full-thickness palatal grafts were harvested with a scalpel. In the test group (LDEE), deepithelialization was performed extraorally using an Er,Cr:YSGG laser (2780 nm; 2.5 W, 83.3 mJ, 30 Hz, 600 \u00b5m tip). In the control group (DEE), a 15c scalpel was used. All CTGs were applied using the modified coronally advanced tunnel (TUN) technique. Clinical parameters\u2014recession depth (RD), keratinized tissue width (KT), gingival thickness (GT), pocket depth (PD), clinical attachment loss (CAL), pink esthetic score (PES), approximal plaque index (API), mean root coverage (MRC), and complete root coverage (CRC)\u2014were assessed at baseline (T0), 3 months (T1), and 6 months (T2). Results: Both LDEE and DEE groups showed significant improvements in RD, KT, GT, PD, and CAL over time (p &lt; 0.001). At T1 and T2, KT was significantly higher in the LDEE group (T1: 3.73 \u00b1 0.72 mm; T2: 3.98 \u00b1 0.76 mm) compared to the DEE group (T1: 3.21 \u00b1 0.61 mm; T2: 3.44 \u00b1 0.74 mm; p &lt; 0.05). Other parameters (RD, GT, PD, CAL) showed no statistically significant intergroup differences at any time point (p &gt; 0.05). After 6 months, MRC was 95% and CRC 82.6% for LDEE, compared to 94.8% and 82.6% for DEE (p &gt; 0.05). PES scores were similar between groups at all time points (p &gt; 0.05). Conclusions: Both laser- and scalpel-deepithelialized grafts effectively treated gingival recessions. LDEE combined with TUN resulted in significantly greater KT width compared to DEE + TUN.<\/jats:p>","DOI":"10.3390\/jcm14155335","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T08:00:41Z","timestamp":1753776041000},"page":"5335","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Efficacy of Er,Cr:YSGG Laser for Deepithelialization of Free Gingival Grafts in Gingival Recession Treatment: A Randomized, Split-Mouth Clinical Trial"],"prefix":"10.3390","volume":"14","author":[{"given":"Artur","family":"Bany\u015b","sequence":"first","affiliation":[{"name":"EMDOLA\u2014European Master Degree in Oral Laser Application, Wroclaw Medical University, 50-367 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3173-9389","authenticated-orcid":false,"given":"Jakub","family":"Fiegler-Rudol","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6109-6809","authenticated-orcid":false,"given":"Zuzanna","family":"Grzech-Le\u015bniak","sequence":"additional","affiliation":[{"name":"Department of Experimental Dentistry, Faculty of Medicine and Dentistry, Wroclaw Medical University, 50-367 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5673-7413","authenticated-orcid":false,"given":"Rafa\u0142","family":"Wiench","sequence":"additional","affiliation":[{"name":"Department of Periodontal Diseases and Oral Mucosa Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3801-0218","authenticated-orcid":false,"given":"Jacek","family":"Matys","sequence":"additional","affiliation":[{"name":"Dental Surgery Department, Faculty of Medicine and Dentistry, Wroclaw Medical University, 50-367 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamil A.","family":"Shibli","sequence":"additional","affiliation":[{"name":"Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo 05652-900, Brazil"},{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07000-000, Brazil"},{"name":"Department of Oral Medicine, Infection, and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5700-4577","authenticated-orcid":false,"given":"Kinga","family":"Grzech-Le\u015bniak","sequence":"additional","affiliation":[{"name":"Laser Laboratory, Department of Integrated Dentistry, Faculty of Medicine and Dentistry, Wroclaw Medical University, 50-425 Wroclaw, Poland"},{"name":"Department of Periodontics, School of Dentistry, Virginia Commonwealth University (VCA), Richmond, VA 23298, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/idj.12617","article-title":"Treatment of Gingival Recession: When and How?","volume":"71","author":"Imber","year":"2021","journal-title":"Int. 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