{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:06:00Z","timestamp":1773705960178,"version":"3.50.1"},"reference-count":135,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Burrough Wellcome Fund Physician Scientist Institutional Award to the Texas A&amp;M University Academy of Physician Scientists"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Liver transplantation (LT) for hepatic malignancies is becoming increasingly common, largely because it offers superior survival relative to other treatment approaches. LT is well-accepted for primary liver cancers such as hepatocellular carcinoma and perihilar cholangiocarcinoma and is being increasingly accepted for intrahepatic cholangiocarcinoma and metastases of colorectal cancer or neuroendocrine tumors to the liver. Over time, indications for transplant oncology have broadened, as has the acceptable disease burden for transplantation, particularly with the advent of new neoadjuvant therapies. Other current frontiers in the field include expanding the donor pool through living donors, extended criteria donors, machine perfusion and increasing access to LT for people from disadvantaged socioeconomic backgrounds. Expanding access to LT can offer renewed hope for long-term survival to patients with primary and secondary liver cancer.<\/jats:p>","DOI":"10.3390\/jcm14155365","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T16:16:10Z","timestamp":1753805770000},"page":"5365","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Liver Transplantation for Cancer\u2014Current Challenges and Emerging Solutions"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0827-8241","authenticated-orcid":false,"given":"Steven M.","family":"Elzein","sequence":"first","affiliation":[{"name":"Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street Suite 1661, Houston, TX 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1734-5959","authenticated-orcid":false,"given":"Elizabeth W.","family":"Brombosz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street Suite 1661, Houston, TX 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudha","family":"Kodali","sequence":"additional","affiliation":[{"name":"Sherrie and Alan Conover Center for Liver Disease and Transplantation, J.C. 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