{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:13:07Z","timestamp":1793391187951,"version":"4.5.0"},"reference-count":77,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The management of adult spinal deformity (ASD) has evolved dramatically over the past century, transitioning from external bracing and in situ fusion to complex, technology-driven surgical interventions. This review traces the historical development of spinal deformity correction and highlights contemporary enabling technologies that are redefining the surgical landscape. Advances in stereoradiographic imaging now allow for precise, low-dose three-dimensional assessment of spinopelvic parameters and segmental bone density, facilitating individualized surgical planning. Robotic assistance and intraoperative navigation improve the accuracy and safety of instrumentation, while patient-specific rods and interbody implants enhance biomechanical conformity and alignment precision. Machine learning and predictive modeling tools have emerged as valuable adjuncts for risk stratification, surgical planning, and outcome forecasting. Minimally invasive deformity correction strategies, including anterior column realignment and circumferential minimally invasive surgery (cMIS), have demonstrated equivalent clinical and radiographic outcomes to traditional open surgery with reduced perioperative morbidity in select patients. Despite these advancements, complications such as proximal junctional kyphosis and failure remain prevalent. Adjunctive strategies\u2014including ligamentous tethering, modified proximal fixation, and vertebral cement augmentation\u2014offer promising preventive potential. Collectively, these innovations signal a paradigm shift toward precision spine surgery, characterized by data-informed decision-making, individualized construct design, and improved patient-centered outcomes in spinal deformity care.<\/jats:p>","DOI":"10.3390\/jcm14155377","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:55:37Z","timestamp":1753872937000},"page":"5377","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Utility of Enabling Technologies in Spinal Deformity Surgery: Optimizing Surgical Planning and Intraoperative Execution to Maximize Patient Outcomes"],"prefix":"10.3390","volume":"14","author":[{"given":"Nora C.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY 10016, USA"},{"name":"Department of Neurosurgery, Rush University Medical Center, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1960-0789","authenticated-orcid":false,"given":"Eli","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Duke University School of Medicine, Durham, NC 27710, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"DeWald","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rush University Medical Center, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Lee","sequence":"additional","affiliation":[{"name":"Midwest Orthopaedics at Rush, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rush University Medical Center, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s11999-009-0888-5","article-title":"A History of Bracing for Idiopathic Scoliosis in North America","volume":"468","author":"Fayssoux","year":"2010","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.3171\/foc.2003.14.1.2","article-title":"History of Surgery for the Correction of Spinal Deformity","volume":"14","author":"Mohan","year":"2003","journal-title":"Neurosurg. Focus"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/00003086-198203000-00028","article-title":"Segmental Spinal Instrumentation for Correction of Scoliosis","volume":"163","author":"Luque","year":"1982","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2106\/00004623-195840030-00003","article-title":"The Milwaukee brace","volume":"40","author":"Blount","year":"1958","journal-title":"J. Bone Joint Surg. Am."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"108","DOI":"10.14531\/ss2016.3.108-113","article-title":"3D analysis of scoliotic deformity development and 3D chain of balance in a scoliosis patient","volume":"13","author":"Dubousset","year":"2016","journal-title":"Russ. J. Spine Surg. (Khirurgiya Pozvonochnika)"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13013-017-0149-4","article-title":"Three-Dimensional Reconstructions of Lenke 1A Curves","volume":"13","author":"Bernard","year":"2018","journal-title":"Scoliosis Spinal Disord."},{"key":"ref_7","first-page":"127","article-title":"The history of vertebral screw and pedicle screw fixation","volume":"11","author":"Kabins","year":"1991","journal-title":"Iowa Orthop. J"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Shakeri, M., Mahdavi, S.M., Rikhtehgar, M., Soleimani, M., Ghandhari, H., Jafari, B., and Daneshmand, S. (2024). EOS\u00ae Is Reliable to Evaluate Spinopelvic Parameters: A Validation Study. BMC Med. Imaging, 24.","DOI":"10.1186\/s12880-023-01178-0"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1243\/09544119JEIM450","article-title":"Bone Mineral Density Assessment Using the EOS Low-Dose X-Ray Device: A Feasibility Study","volume":"222","author":"Sapin","year":"2008","journal-title":"Proc. Inst. Mech. Eng. H"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s43390-021-00403-6","article-title":"State of the Art Review of New Technologies in Spine Deformity Surgery-Robotics and Navigation","volume":"10","author":"Sielatycki","year":"2022","journal-title":"Spine Deform."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e342","DOI":"10.1016\/j.ejrad.2013.02.015","article-title":"The EOS 2D\/3D X-ray imaging system: A cost-effectiveness analysis quantifying the health benefits from reduced radiation exposure","volume":"82","author":"Faria","year":"2013","journal-title":"Eur. J. Radiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta16140","article-title":"EOS 2D\/3D X-ray imaging system: A systematic review and economic evaluation","volume":"16","author":"McKenna","year":"2012","journal-title":"Health Technol. Assess."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.14245\/ns.2347184.592","article-title":"Navigation-Guided\/Robot-Assisted Spinal Surgery: A Review Article","volume":"21","author":"Lee","year":"2024","journal-title":"Neurospine"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"86","DOI":"10.21037\/atm-2020-ioi-07","article-title":"The Current State of Navigation in Robotic Spine Surgery","volume":"9","author":"Huang","year":"2021","journal-title":"Ann. Transl. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1177\/21925682211004250","article-title":"Adult Spinal Deformity Surgery and Frailty: A Systematic Review","volume":"12","author":"Georgiopoulos","year":"2022","journal-title":"Glob. Spine J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"E10","DOI":"10.3171\/2021.10.FOCUS21509","article-title":"Evaluating robotic pedicle screw placement against conventional modalities: A systematic review and network meta-analysis","volume":"52","author":"Naik","year":"2022","journal-title":"Neurosurg. Focus"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.spinee.2020.09.007","article-title":"Safety and accuracy of robot-assisted placement of pedicle screws compared to conventional free-hand technique: A systematic review and meta-analysis","volume":"21","author":"Fatima","year":"2021","journal-title":"Spine J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.14444\/8140","article-title":"Role of Robotics in Adult Spinal Deformity","volume":"15","author":"Cronin","year":"2021","journal-title":"Int. J. Spine Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1093\/neuros\/nyy630","article-title":"Image-Guided Navigation and Robotics in Spine Surgery","volume":"84","author":"Kochanski","year":"2019","journal-title":"Neurosurgery"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"E3","DOI":"10.3171\/2021.10.FOCUS21496","article-title":"Learning curves in robot-assisted spine surgery: A systematic review and proposal of application to residency curricula","volume":"52","author":"Pennington","year":"2022","journal-title":"Neurosurg. Focus"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"McNamee, C., Kelly, D., McDonnell, J.M., Sowa, A.M., Pearl, A.M., Darwish, S., and Butler, J.S. (2025). The learning curve of robotic-assisted pedicle screw placement: An individual patient data meta-analysis. Spine J., S1529-9430(25)00343-2.","DOI":"10.1016\/j.spinee.2025.07.007"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Sturgill, D., How, J., Blajda, T., Davis, Z., Ali, M., O\u2019MAlley, G., Patel, N.V., Khan, M.F., and Goldstein, I. (2024). Are the clinical outcomes and cost-effectiveness of robot-assisted pedicle screw placement in lumbar fusion surgery superior to computed tomography navigation and free-hand fluoroscopy-guided techniques?. World Neurosurg., Epub ahead of print.","DOI":"10.1016\/j.wneu.2024.08.018"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2015.11.SPINE151036","article-title":"Prospective Multicenter Assessment of Perioperative and Minimum 2-Year Postoperative Complication Rates Associated with Adult Spinal Deformity Surgery","volume":"25","author":"Smith","year":"2016","journal-title":"J. Neurosurg. Spine"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3171\/2019.7.SPINE181104","article-title":"The MISDEF2 Algorithm: An Updated Algorithm for Patient Selection in Minimally Invasive Deformity Surgery","volume":"32","author":"Mummaneni","year":"2019","journal-title":"J. Neurosurg. Spine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3171\/2021.3.SPINE201825","article-title":"Patient Outcomes after Circumferential Minimally Invasive Surgery Compared with Those of Open Correction for Adult Spinal Deformity: Initial Analysis of Prospectively Collected Data","volume":"36","author":"Chou","year":"2021","journal-title":"J. Neurosurg. Spine"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.14245\/ns.1836022.011","article-title":"Minimally Invasive Spinal Surgery for Adult Spinal Deformity","volume":"15","author":"Bae","year":"2018","journal-title":"Neurospine"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"E210","DOI":"10.1097\/BRS.0000000000005011","article-title":"Comparison of open surgery versus minimally invasive surgery in nonsevere adult degenerative scoliosis: A systematic review and meta-analysis","volume":"49","author":"Shao","year":"2024","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10143-020-01280-9","article-title":"Minimally invasive versus open surgery for the correction of adult degenerative scoliosis: A systematic review","volume":"44","author":"Lak","year":"2021","journal-title":"Neurosurg. Rev."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.3171\/2014.3.FOCUS1424","article-title":"Comparison of radiographic results after minimally invasive, hybrid, and open surgery for adult spinal deformity: A multicenter study of 184 patients","volume":"36","author":"Haque","year":"2014","journal-title":"Neurosurg. Focus"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/neuros\/nyw072","article-title":"Does MIS surgery allow for shorter constructs in the surgical treatment of adult spinal deformity?","volume":"80","author":"Uribe","year":"2017","journal-title":"Neurosurgery"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3171\/2020.4.SPINE20169","article-title":"Factors affecting approach selection for minimally invasive versus open surgery in the treatment of adult spinal deformity: Analysis of a prospective, nonrandomized multicenter study","volume":"33","author":"Park","year":"2020","journal-title":"J. Neurosurg. Spine"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3171\/2024.1.SPINE231252","article-title":"Development and Validation of an Artificial Intelligence Model to Accurately Predict Spinopelvic Parameters","volume":"41","author":"Harake","year":"2024","journal-title":"J. Neurosurg. Spine"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00586-018-5816-5","article-title":"Predictive Model for Major Complications 2 Years after Corrective Spine Surgery for Adult Spinal Deformity","volume":"28","author":"Yagi","year":"2019","journal-title":"Eur. Spine J."},{"key":"ref_34","first-page":"53","article-title":"Machine Learning in Spine Surgery: A Narrative Review","volume":"94","author":"Adida","year":"2024","journal-title":"Neurosurgery"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Khan, J.A., Houdane, A., Hajja, A., Nassar, J.E., Alsoof, D., Diebo, B.G., Sardar, Z.M., Abd-El-Barr, M.M., Bourghli, A., and Konbaz, F. (2025). Assessing the Utility and Challenges of Machine Learning in Spinal Deformity Management: A Systematic Review. Spine (Phila Pa 1976).","DOI":"10.1097\/BRS.0000000000005236"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jspd.2018.03.003","article-title":"Predicting Surgical Complications in Patients Undergoing Elective Adult Spinal Deformity Procedures Using Machine Learning","volume":"6","author":"Kim","year":"2018","journal-title":"Spine Deform."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1302\/0301-620X.107B3.BJJ-2024-1220.R1","article-title":"Machine-Learning Models for the Prediction of Ideal Surgical Outcomes in Patients with Adult Spinal Deformity","volume":"107-B","author":"Wang","year":"2025","journal-title":"Bone Joint J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e691","DOI":"10.1016\/j.wneu.2024.02.112","article-title":"Deep Learning Prediction of Cervical Spine Surgery Revision Outcomes Using Standard Laboratory and Operative Variables","volume":"185","author":"Schonfeld","year":"2024","journal-title":"World Neurosurg."},{"key":"ref_39","first-page":"e48078","article-title":"Machine Learning Applications in Spine Surgery","volume":"15","author":"Tragaris","year":"2023","journal-title":"Cureus"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1177\/21925682241277771","article-title":"Explainable Machine Learning Approach to Prediction of Prolonged Intensive Care Unit Stay in Adult Spinal Deformity Patients: Machine Learning Outperforms Logistic Regression","volume":"15","author":"Zaidat","year":"2025","journal-title":"Glob. Spine J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1007\/s00586-019-06236-2","article-title":"3D-Printed Spine Surgery Implants: A Systematic Review of the Efficacy and Clinical Safety Profile of Patient-Specific and off-the-Shelf Devices","volume":"29","author":"Burnard","year":"2020","journal-title":"Eur. Spine J."},{"key":"ref_42","first-page":"100559","article-title":"Patient-Specific Implants and Spinal Alignment Outcomes","volume":"20","author":"Laynes","year":"2024","journal-title":"N. Am. Spine Soc. J."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1097\/BSD.0000000000001026","article-title":"3D-Printed Patient-Specific Spine Implants: A Systematic Review","volume":"33","author":"Wallace","year":"2020","journal-title":"Clin. Spine Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.14444\/8636","article-title":"Radiographic Alignment in Deformity Patients Treated with Personalized Interbody Devices: Early Experience from the COMPASS Registry","volume":"18","author":"Kent","year":"2024","journal-title":"Int. J. Spine Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1177\/21925682221134913","article-title":"Biomechanical Comparison of Subsidence Between Patient-Specific and Non-Patient-Specific Lumbar Interbody Fusion Cages","volume":"14","author":"Fernandes","year":"2024","journal-title":"Glob. Spine J."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"297","DOI":"10.25259\/SNI_460_2024","article-title":"Recent Advances of 3D-Printing in Spine Surgery","volume":"15","author":"Iqbal","year":"2024","journal-title":"Surg. Neurol. Int."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"100021","DOI":"10.1016\/j.stlm.2021.100021","article-title":"Additive Manufacturing for Metallic Spinal Implants: A Systematic Review","volume":"3","author":"Meena","year":"2021","journal-title":"Ann. 3D Print. Med."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s43390-023-00805-8","article-title":"Patient-Specific Rods in Adult Spinal Deformity: A Systematic Review","volume":"12","author":"Picton","year":"2024","journal-title":"Spine Deform."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.14444\/8642","article-title":"Patient-Specific Rods in Adolescent and Adult Spinal Deformity Surgery: A Narrative Review","volume":"18","author":"Bautista","year":"2024","journal-title":"Int. J. Spine Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.neuchi.2019.12.015","article-title":"\u201cPatient-Specific\u201d Rods in the Management of Adult Spinal Deformity. One-Year Radiographic Results of a Prospective Study about 86 Patients","volume":"66","author":"Prost","year":"2020","journal-title":"Neurochirurgie"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"65","DOI":"10.21037\/jss-24-75","article-title":"The Impact of Patient-Specific Spine Rods on Spinopelvic Parameters after Short Segment Degenerative Lumbar Fusions","volume":"11","author":"Drexelius","year":"2025","journal-title":"J. Spine Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"409","DOI":"10.21037\/jss-23-85","article-title":"Patient-Specific Spinal Rods in Adult Spinal Deformity Surgery Reduce Proximal Junctional Failure: A Review of Patient Outcomes and Surgical Technique in a Prospective Observational Cohort","volume":"9","author":"Faulks","year":"2023","journal-title":"J. Spine Surg."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"116","DOI":"10.62713\/aic.3367","article-title":"Patient-Specific Rods vs Traditional Rods in Surgical Correction of Adult Spinal Deformities: A Case-Matched Study","volume":"96","author":"Nasto","year":"2025","journal-title":"Ann. Ital. Chir."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/BSD.0000000000000721","article-title":"Patient-Specific Rods for Surgical Correction of Sagittal Imbalance in Adults: Technical Aspects and Preliminary Results","volume":"32","author":"Solla","year":"2019","journal-title":"Clin. Spine Surg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"863","DOI":"10.14245\/ns.2346476.238","article-title":"Proximal Junctional Kyphosis or Failure After Adult Spinal Deformity Surgery\u2014Review of Risk Factors and Its Prevention","volume":"20","author":"Lee","year":"2023","journal-title":"Neurospine"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s43390-023-00698-7","article-title":"Evaluation of Intraoperative Coronal Alignment Using a Computer-Assisted Rod Bending System (CARBS) without Intraoperative Radiation Exposure in Adult Spinal Deformity Surgery: A Technical Note and Preliminary Results","volume":"11","author":"Takeuchi","year":"2023","journal-title":"Spine Deform."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"994","DOI":"10.3171\/2014.9.SPINE131176","article-title":"Prospective Multicenter Assessment of Risk Factors for Rod Fracture Following Surgery for Adult Spinal Deformity","volume":"21","author":"Smith","year":"2014","journal-title":"J. Neurosurg. Spine"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.spinee.2023.01.007","article-title":"Characterization of Ion Release from a Novel Biomaterial, Molybdenum-47.5Rhenium, in Physiologic Environments","volume":"23","author":"Mok","year":"2023","journal-title":"Spine J."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.14245\/ns.2448734.367","article-title":"Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients with Adult Spinal Deformity: Risk Factor Analysis of 196 Cases Undergoing Low Thoracic to Pelvic Fusion","volume":"21","author":"Park","year":"2024","journal-title":"Neurospine"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/ons\/opy065","article-title":"A Pilot Study on Posterior Polyethylene Tethers to Prevent Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity","volume":"16","author":"Buell","year":"2019","journal-title":"Oper. Neurosurg."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3171\/2018.10.SPINE18429","article-title":"Optimal Tether Configurations and Preload Tensioning to Prevent Proximal Junctional Kyphosis: A Finite Element Analysis","volume":"30","author":"Buell","year":"2019","journal-title":"J. Neurosurg. Spine"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3171\/2016.6.SPINE151477","article-title":"The Effect of Posterior Polyester Tethers on the Biomechanics of Proximal Junctional Kyphosis: A Finite Element Analysis","volume":"26","author":"Bess","year":"2017","journal-title":"J. Neurosurg. Spine"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"8620","DOI":"10.14444\/8620","article-title":"Risk Factors for Recurrent Proximal Junctional Failure Following Adult Spinal Deformity Surgery: Analysis of 60 Patients Undergoing Fusion Extension Surgery for Proximal Junctional Failure","volume":"18","author":"Park","year":"2024","journal-title":"Int. J. Spine Surg."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"622","DOI":"10.31616\/asj.2018.12.4.622","article-title":"Effect of Different Types of Upper Instrumented Vertebrae Instruments on Proximal Junctional Kyphosis Following Adult Spinal Deformity Surgery: Pedicle Screw versus Transverse Process Hook","volume":"12","author":"Matsumura","year":"2018","journal-title":"Asian Spine J."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1097\/BRS.0000000000001043","article-title":"Prevention of Acute Proximal Junctional Fractures After Long Thoracolumbar Posterior Fusions for Adult Spinal Deformity Using 2-Level Cement Augmentation at the Upper Instrumented Vertebra and the Vertebra 1 Level Proximal to the Upper Instrumented Vertebra","volume":"40","author":"Theologis","year":"2015","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.spinee.2017.05.017","article-title":"The Effect of Prophylactic Vertebroplasty on the Incidence of Proximal Junctional Kyphosis and Proximal Junctional Failure Following Posterior Spinal Fusion in Adult Spinal Deformity: A 5-Year Follow-up Study","volume":"17","author":"Raman","year":"2017","journal-title":"Spine J."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s00198-016-3865-3","article-title":"The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA","volume":"28","author":"Wright","year":"2017","journal-title":"Osteoporos. Int."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1093\/neuros\/nyab317","article-title":"Congress of Neurological Surgeons Systematic Review and Evidence-based Guidelines for Perioperative Spine: Preoperative osteoporosis assessment","volume":"89","author":"Dimar","year":"2021","journal-title":"Neurosurgery"},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Yao, Y.-C., Chao, H., Kao, K.-Y., and Chou, P.-H. (2023). CT Hounsfield unit is a reliable parameter for screw loosening or cage subsidence in minimally invasive transforaminal lumbar interbody fusion. Sci. Rep., 13.","DOI":"10.1038\/s41598-023-28555-7"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1210\/endrev\/bnac031","article-title":"Bone turnover markers: Basic biology to clinical applications","volume":"44","author":"Schini","year":"2023","journal-title":"Endocr. Rev."},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"U.S. Preventive Services Task Force, Curry, S.J., Krist, A.H., Owens, D.K., Barry, M.J., Caughey, A.B., Davidson, K.W., Doubeni, C.A., Epling, J.W., and Kemper, A.R. (2025). Screening for Osteoporosis to Prevent Fractures: Recommendation Statement. JAMA, 333, 498\u2013508.","DOI":"10.1001\/jama.2024.27154"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/BRS.0000000000004268","article-title":"Best practice guidelines for assessment and management of osteoporosis in adult patients undergoing elective spinal reconstruction","volume":"47","author":"Sardar","year":"2022","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref_73","first-page":"S1529-9430(25)00204-9","article-title":"Anti-osteoporosis medication in patients with posterior spine fusion: A systematic review and meta-analysis","volume":"45","author":"Jin","year":"2025","journal-title":"Spine J."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Al-Najjar, Y.A., Quraishi, D.A., Kumar, N., and Hussain, I. (2024). Bone Health Optimization in Adult Spinal Deformity Patients: A Narrative Review. J. Clin. Med., 13.","DOI":"10.3390\/jcm13164891"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1007\/s40618-024-02395-2","article-title":"A practical approach for anabolic treatment of bone fragility with romosozumab","volume":"47","author":"Cianferotti","year":"2024","journal-title":"J. Endocrinol. 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