{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:21:38Z","timestamp":1790108498187,"version":"4.0.1"},"reference-count":32,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Laboratory on Human Reproduction","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: Diabetes in pregnancy represents a significant public health concern with established impacts on both maternal and fetal health outcomes. Our aim was to evaluate the epidemiology of diabetes mellitus in pregnancy (DMP) and specific fetal and neonatal transient metabolic disorders (FNTMDs) in Hungary between 2010 and 2024, as well as to project future trends through to 2035. Methods: We carried out a quantitative, retrospective study using nationwide real-world data from the Hungarian \u2018Pulvita\u2019 Health Data Warehouse. ICD-10 codes O24.0\u2013O24.9 (DMP) and P70.0\u2013P70.9 (FNTMDs) were included. Annual patient numbers, the number of hospital days, and the number of DMP patients per 1000 women aged 15\u201349, as well as the number of FNTMD patients per 1000 live births, were analyzed with joinpoint regression analysis and different forecasting models to project future prevalence up to 2035. Results: Despite a 14.2% decrease in live births, DMP cases increased significantly (54.9% inpatient, 26.6% outpatient), with GDM incidence per thousand reproductive-age women rising by 85.7%. FNTMD cases showed similar trends, with GDM-related infant syndromes more than doubling (154% increase). Projections indicate that DMP prevalence could reach 4.60 per 1000 reproductive-age women by 2035, while FNTMD cases show varying trends between inpatient (increasing) and outpatient (stabilizing) care. Conclusions: These findings demonstrate a continuing upward trend in diabetes-related pregnancy complications, despite shorter hospital stays, suggesting an urgent need for enhanced preventive programs and specialized care service planning.<\/jats:p>","DOI":"10.3390\/jcm14165740","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T15:44:21Z","timestamp":1755186261000},"page":"5740","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Trends and Projections of the Prevalence of Diabetes Mellitus in Pregnancy and Fetal\u2013Neonatal Metabolic Disorders, 2010\u20132035: A Nationwide Population-Based Study from Hungary"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3339-4953","authenticated-orcid":false,"given":"T\u00edmea","family":"Cs\u00e1kv\u00e1ri","sequence":"first","affiliation":[{"name":"Department of Health Economics and Health Care Management, Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 33 Landorhegyi Street, H-8900 Zalaegerszeg, Hungary"},{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di\u00e1na","family":"Elmer","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"},{"name":"Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 3 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina","family":"Palkovics","sequence":"additional","affiliation":[{"name":"Department of Health Economics and Health Care Management, Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 33 Landorhegyi Street, H-8900 Zalaegerszeg, Hungary"},{"name":"Doctoral School of Health Sciences, Faculty of Health Sciences, University of P\u00e9cs, 4 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0574-5787","authenticated-orcid":false,"given":"Luca Fanni","family":"S\u00e1ntics-Kajos","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"},{"name":"Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 3 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"Doctoral School of Health Sciences, Faculty of Health Sciences, University of P\u00e9cs, 4 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1lm\u00e1n","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"},{"name":"Department of Obstetrics and Gynaecology, Clinical Centre, University of P\u00e9cs, 17 \u00c9desany\u00e1k Street, H-7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"B\u00f3dis","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"},{"name":"Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 3 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"},{"name":"Department of Obstetrics and Gynaecology, Clinical Centre, University of P\u00e9cs, 17 \u00c9desany\u00e1k Street, H-7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3699-6236","authenticated-orcid":false,"given":"Imre","family":"Boncz","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 4 Vasv\u00e1ri P\u00e1l Street, H-7622 P\u00e9cs, Hungary"},{"name":"Institute of Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 3 V\u00f6r\u00f6smarty Street, H-7621 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"ref_1","unstructured":"International Diabetes Federation (2025). 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