{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:07:51Z","timestamp":1790633271195,"version":"4.1.0"},"reference-count":36,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: To evaluate the safety and feasibility of continuous positive airway pressure (CPAP) in patients with acute myocardial infarction (AMI) and acute decompensated heart failure (ADHF) during percutaneous coronary intervention (PCI). Non-invasive ventilation (NIV) is an established treatment for ADHF. Methods: All consecutive patients admitted to Santa Croce Hospital of Cuneo, receiving CPAP for ADHF in the cath lab during PCI for AMI, were included in a case series. Results: Between December 2018 and March 2021, 25 pts were included (median age 78 yrs, 48% female), with 64% of patients presenting with ST-elevation AMI and 17 (69%) in cardiogenic shock. At admission median left ventricular ejection fraction was 35 (20\u201360)% and eight (32%) patients had severe mitral regurgitation. Median PaO2\/FiO2 was 183 (141\u2013261) mmHg\/%, lactate level 2.4 (1.3\u20133.8) mmol\/L, and NTproBNP 7882 (3139\u201335,000) ng\/L. CPAP was positioned and managed by nurses in all cases. Median FiO2 was 50 (35\u2013100)% and median positive end-expiratory pressure was 7.5 (5\u201312) cmH2O. CPAP was generally well tolerated in 22 (88%) patients. One patient suffered cardiac arrest that led to CPAP interruption due to resuscitation maneuvers. No patient required orotracheal intubation in the cath lab. The post-procedural PaO2\/FiO2 ratio substantially improved to 230 (175\u2013356) mmHg\/% (p = 0.007) and lactate decreased to 1.5 (1.0\u20131) mmol\/L (p = 0.002). One patient died during hospital stay due to underlying disease, unrelated to the study procedure. Conclusions: CPAP during PCI in patients with AMI and ADHF seems feasible, safe, and well tolerated. Larger studies are warranted to confirm these results.<\/jats:p>","DOI":"10.3390\/jcm14165756","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T15:44:21Z","timestamp":1755186261000},"page":"5756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Use of Continuous Positive Airway Pressure Ventilation as a Support During Coronary Angioplasty in Patients with Acute Myocardial Infarction: Safety and Feasibility"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8333-672X","authenticated-orcid":false,"given":"Francesca","family":"Giordana","sequence":"first","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4711-0891","authenticated-orcid":false,"given":"Filippo","family":"Angelini","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, Citt\u00e0 della Salute e della Scienza, 10126 Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Gribaudo","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Baralis","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian Andrea","family":"Cinconze","sequence":"additional","affiliation":[{"name":"Divisione di Cardiologia, Ospedale Civile di Vigevano, 27029 Vigevano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"De Benedetto Fabrizi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Battaglia","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"De Stefanis","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medical Sciences, Citt\u00e0 della Salute e della Scienza Hospital, University of Turin, 10124 Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Verra","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medical Sciences, Citt\u00e0 della Salute e della Scienza Hospital, University of Turin, 10124 Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Rossini","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Santa Croce and Carle Hospital, 12100 Cuneo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jchf.2017.09.015","article-title":"Post-Myocardial Infarction Heart Failure","volume":"6","author":"Bahit","year":"2018","journal-title":"JACC Heart Fail."},{"key":"ref_2","first-page":"326","article-title":"FAST-MI Investigators. 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