{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T23:24:49Z","timestamp":1780356289368,"version":"3.54.1"},"reference-count":20,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chinese Society of Cardiology Foundation","award":["CSCF2020B03"],"award-info":[{"award-number":["CSCF2020B03"]}]},{"name":"Chinese Society of Cardiology Foundation","award":["8187021109"],"award-info":[{"award-number":["8187021109"]}]},{"name":"Chinese Society of Cardiology Foundation","award":["8207021929"],"award-info":[{"award-number":["8207021929"]}]},{"name":"Chinese Society of Cardiology Foundation","award":["82100510"],"award-info":[{"award-number":["82100510"]}]},{"name":"Chinese Society of Cardiology Foundation","award":["81800411"],"award-info":[{"award-number":["81800411"]}]},{"name":"National Natural Science Foundation of China","award":["CSCF2020B03"],"award-info":[{"award-number":["CSCF2020B03"]}]},{"name":"National Natural Science Foundation of China","award":["8187021109"],"award-info":[{"award-number":["8187021109"]}]},{"name":"National Natural Science Foundation of China","award":["8207021929"],"award-info":[{"award-number":["8207021929"]}]},{"name":"National Natural Science Foundation of China","award":["82100510"],"award-info":[{"award-number":["82100510"]}]},{"name":"National Natural Science Foundation of China","award":["81800411"],"award-info":[{"award-number":["81800411"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective: The purpose of this study was to report the clinical characteristics and prognosis of spontaneous isolated abdominal aortic dissection (SIAAD) based on the dissection length. Methods: Between March 2012 and September 2023, 159 of 7572 patients with aortic dissection were diagnosed with SIAAD and enrolled in the retrospective study. We proposed a new morphologic classification: extensive SIAAD (e-SIAAD) and focal SIAAD (f-SIAAD), based on whether the dissection length exceeds 50 mm or not. The clinical baseline, computed tomography angiography (CTA) findings, and long-term follow-up of the two types were compared. Results: SIAAD prevalence was 2.1%. Patients with f-SIAAD were significantly older (63.74 \u00b1 10.97 vs. 50.70 \u00b1 10.10 years, p &lt; 0.001), had more atherosclerosis risk factors, arteriosclerosis, and penetrating aortic ulcers compared to e-SIAAD patients. Conversely, e-SIAAD presented more acutely (72.97% vs. 34.12%, p = 0.001), exhibited more frequent symptoms (85.14% vs. 61.18%, p = 0.0037), larger dissection diameters (31.89 \u00b1 10.99 vs. 24.41 \u00b1 11.28 mm, p = 0.001), and greater involvement of the renal and iliac arteries. Treatment involved medical management (30%), endovascular repair (65%), or surgery (2.5%), without significant differences between groups. In-hospital mortality was higher in f-SIAAD (six deaths vs. one in e-SIAAD). During median follow-up of 48 months (range, 6\u2013148 months), mortality was higher in f-SIAAD (70% vs. 90% estimated 10-year survival). Conclusions: SIAAD classification by dissection length revealed significant differences in clinical presentation, CTA characteristics, and prognosis. Focal dissections correlated with advanced age, severe arteriosclerosis, and poorer long-term outcomes, emphasizing the need for tailored management approaches.<\/jats:p>","DOI":"10.3390\/jcm14165849","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:59:01Z","timestamp":1755601141000},"page":"5849","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Characteristics and Prognosis in Spontaneous Isolated Abdominal Aortic Dissection Based on the Dissection Length"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2513-4502","authenticated-orcid":false,"given":"Saddam","family":"Shaiea","sequence":"first","affiliation":[{"name":"Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingwei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussen","family":"Mansai","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Mayo Clinic Health System, Mankato, MN 56001, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Aldali","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulwahab","family":"Hashem","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Heng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5160-4427","authenticated-orcid":false,"given":"Hesong","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/jcu.23889","article-title":"Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection","volume":"53","author":"Tsubouchi","year":"2025","journal-title":"J. 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