{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:25:15Z","timestamp":1778549115501,"version":"3.51.4"},"reference-count":21,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T00:00:00Z","timestamp":1757203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Dentaurum","award":["032-062"],"award-info":[{"award-number":["032-062"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Class II is considered one of the most common malocclusions, influencing 37% of schoolchildren in Europe and 33% of orthodontic patients in the United States. When this type of malocclusion is combined with increased overjet with proclined teeth and maxillary excess, then moving maxillary molars distally is suggested. According to the recent literature, modern appliances that lack patient cooperation can be combined with temporary anchorage devices to provide absolute and skeletal anchorage while supporting the non-compliance appliances to eliminate their side effects, such as anterior and posterior anchorage loss along with maxillary molar inclination and rotation. To counteract these limitations, the Advanced Molar Distalization Appliance (amda\u00ae), a non-compliance appliance for maxillary molar distalization supported by two mini-implants (MIs) with anterior abutments, was recently developed. Methods: In this preliminary prospective clinical trial, eight consecutive patients treated with the amda\u00ae are evaluated through lateral cephalometric radiographs, while its application, construction, and anchorage is presented and discussed. The evaluation of dentoalveolar and skeletal changes has been made with 14 variables measured on the pre- and post-cephalometric radiographs before and immediately after maxillary molar distalization (T0 and T1, respectively), along with cephalometric superimpositions by the structural method. Results: In total, the mean distal molar movement was 4.2 \u00b1 1.37 mm, the mean distal tipping was 1.7 \u00b1 1.9 degrees, and the vertical movement was 1.6 \u00b1 2.6 mm. Conclusions: The amda\u00ae seems to provide an ideal option for treating patients with Class II malocclusion, achieving bodily movement of the maxillary molars with only minimal distal tipping and no anchorage loss.<\/jats:p>","DOI":"10.3390\/jcm14176323","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T11:51:12Z","timestamp":1757332272000},"page":"6323","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of Maxillary Molar Distalization Supported by Mini-Implants with the Advanced Molar Distalization Appliance (amda\u00ae): Preliminary Results of a Prospective Clinical Trial"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5331-1019","authenticated-orcid":false,"given":"Nikolaos","family":"Karvelas","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Department of Orthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aikaterini","family":"Samandara","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9001-5518","authenticated-orcid":false,"given":"Bogdan Radu","family":"Dragomir","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Chehab","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8042-2424","authenticated-orcid":false,"given":"Tinela","family":"Panaite","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Romanec","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7630-7258","authenticated-orcid":false,"given":"Moschos A.","family":"Papadopoulos","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7861-473X","authenticated-orcid":false,"given":"Irina Nicoleta","family":"Zetu","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,7]]},"reference":[{"key":"ref_1","unstructured":"Papadopoulos, M.A. (2006). 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