{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T09:46:13Z","timestamp":1793699173483,"version":"4.5.1"},"reference-count":25,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Each year, the number of kidney transplants (KT) performed in older recipients continues to rise. The process of aging may impact early post-transplant outcomes. The aim of this study was to analyze one-year outcomes, clinical and surgical complications, as well as patient and graft survival in senior recipients. Methods: This retrospective, observational study included a total of 270 participants who underwent KT during the period between January 2021 and April 2024. Recipients were divided into two groups: the older group (\u226560 years; n = 75) and the younger group (&lt;60 years; n = 195) and then analyzed during a one-year follow-up period. Results: Older recipients were characterized by a higher body mass index (MD = 1.77, CI95 [0.63; 2.91], p = 0.002), suffered more often from diabetes mellitus (RR = 2.94, CI95 [1.79; 4.82], p &lt; 0.001), cardiovascular diseases (RR = 5.20, CI95 [2.90; 9.32], p &lt; 0.001) and were more likely to receive a kidney from older (MD = 12.37, CI95 [8.94; 15.80], p &lt; 0.001) deceased (p &lt; 0.001) donors. Senior patients had more infections (p = 0.019) and surgical complications (RR = 1.81, CI95 [1.14; 2.87], p = 0.020), more cardiac events (RR = 2.28, CI95 [1.17; 4.43], p = 0.025), and a higher incidence of delayed graft function (p &lt; 0.001) compared to younger patients. The estimated glomerular filtration rate (eGFR) was significantly lower in the older group both at initial hospital discharge (MD = \u22126.50, CI95 [\u221213.00; \u22123.00], p = 0.004) and at one-year follow-up (MD = \u221211.79, CI95 [\u221217.32; \u22126.25], p &lt; 0.001). No differences were observed in the incidence of biopsy-proven acute rejection, cytomegalovirus replication, and polyomavirus replication. One-year patient and graft survival was 97.3% and 94.7% in the older group, and 98.5% and 96.9% in the younger group, respectively. Conclusions: Kidney transplantation in older recipients is safe in the short term. Although eGFR was lower in the older group, it remained within an acceptable range.<\/jats:p>","DOI":"10.3390\/jcm14186545","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T14:10:19Z","timestamp":1758118219000},"page":"6545","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Kidney Transplantation in Older Recipients: One-Year Outcomes and Complications from a Single-Center Experience"],"prefix":"10.3390","volume":"14","author":[{"given":"Aleksandra","family":"Barbachowska-Kubik","sequence":"first","affiliation":[{"name":"Department of Transplantology, Immunology, Nephrology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Gozdowska","sequence":"additional","affiliation":[{"name":"Department of Transplantology, Immunology, Nephrology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Durlik","sequence":"additional","affiliation":[{"name":"Department of Transplantology, Immunology, Nephrology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1056\/NEJM199912023412303","article-title":"Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant","volume":"341","author":"Wolfe","year":"1999","journal-title":"N. 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