{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:51:02Z","timestamp":1787028662528,"version":"build-2736575974"},"reference-count":26,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The COVID-19 pandemic disrupted healthcare systems globally, with dental services significantly limited due to infection control measures. This study investigates the impact of the pandemic on the clinical presentation, management, and outcomes of odontogenic abscesses over three distinct periods. Methods: A retrospective study was conducted at University Clinical Hospital (Poznan, Poland), which included adult patients hospitalised for odontogenic infections between March 2019 and February 2022. The cohort comprised 101 patients (median age: 33 years; 59.41% male), with admissions distributed across pre-pandemic (37.62%), pandemic (19.80%), and post-pandemic (42.57%) periods. Clinical, biochemical, and radiographic data were analysed. Results: No statistically significant differences were found between periods for abscess severity, hospitalisation length, or inflammatory marker levels. Elevated procalcitonin (Rs = 0.289, p = 0.005), C-reactive protein (Rs = 0.385, p &lt; 0.001), and body mass index (Rs = 0.253, p = 0.011) independently predicted longer hospital stays. In regression modelling, procalcitonin (\u03b2 = 0.464, p = 0.001) and prior outpatient antibiotic use (\u03b2 = 0.281, p = 0.038) were mainly associated with larger abscess volumes, while comorbidities (\u03b2 = 0.262, p = 0.025), longer hospitalisation (\u03b2 = 0.594, p = 0.001) and abscess volume (\u03b2 = \u22120.294, p = 0.040) increased the risk of reoperation. Conclusions: The study highlights clinically important findings linked to delayed dental care and increased systemic inflammation related to the pandemic. Elevated procalcitonin and CRP levels provide prognostic information that can guide early triage, risk stratification, and decisions regarding surgical versus outpatient management. These findings emphasise the importance of maintaining essential dental services, implementing preventive strategies, and optimising management protocols to reduce the risk of severe infections and improve patient outcomes during healthcare disruptions.<\/jats:p>","DOI":"10.3390\/jcm14196953","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T09:37:21Z","timestamp":1759311441000},"page":"6953","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of the COVID-19 Pandemic on Odontogenic Abscess Clinical Patterns and Predictive Factors: A Retrospective Cross-Sectional Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5042-5985","authenticated-orcid":false,"given":"Kacper","family":"Nijakowski","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9129-9737","authenticated-orcid":false,"given":"Stanis\u0142aw","family":"Ksel","sequence":"additional","affiliation":[{"name":"The Student Scientific Society, Poznan University of Medical Sciences, 60-806 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olesya","family":"Marushko","sequence":"additional","affiliation":[{"name":"The Student Scientific Society, Poznan University of Medical Sciences, 60-806 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksy","family":"Nowak","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery, Poznan University of Medical Sciences, 60-355 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0580-8921","authenticated-orcid":false,"given":"Jakub","family":"Jankowski","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2434-4313","authenticated-orcid":false,"given":"Jacek","family":"Kwiatkowski","sequence":"additional","affiliation":[{"name":"Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University in Toru\u0144, 85-067 Bydgoszcz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olena","family":"Marushko","sequence":"additional","affiliation":[{"name":"The Student Scientific Society, Poznan University of Medical Sciences, 60-806 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"S\u0142owik","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery, Poznan University of Medical Sciences, 60-355 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"Ok\u0142a","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery, Poznan University of Medical Sciences, 60-355 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e247553","DOI":"10.1136\/bcr-2021-247553","article-title":"Complications of Dental Infections Due to Diagnostic Delay during COVID-19 Pandemic","volume":"15","year":"2022","journal-title":"BMJ Case Rep. CP"},{"key":"ref_2","unstructured":"Hoerter, J.E., and Malkin, B.D. (2025). Odontogenic Orofacial Space Infections. StatPearls, StatPearls Publishing."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41368-020-0075-9","article-title":"Transmission Routes of 2019-nCoV and Controls in Dental Practice","volume":"12","author":"Peng","year":"2020","journal-title":"Int. J. Oral Sci."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Polskie Towarzystwo Stomatologiczne (2020). COVID-19 a Praca Lekarza Dentysty: Wytyczne PTS Uaktualnione, Polskie Towarzystwo Stomatologiczne.","DOI":"10.21906\/rbl.3655"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.identj.2025.02.024","article-title":"Long-Term Impact of the COVID-19 Pandemic on Dental Care Delivery in Poland: A Single-Center Retrospective Analysis","volume":"75","author":"Ortarzewska","year":"2025","journal-title":"Int. Dent. J."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Nijakowski, K., Cie\u015blik, K., \u0141aganowski, K., Gruszczy\u0144ski, D., and Surdacka, A. (2021). The Impact of the COVID-19 Pandemic on the Spectrum of Performed Dental Procedures. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18073421"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Dickson-Swift, V., Kangutkar, T., Knevel, R., and Down, S. (2022). The Impact of COVID-19 on Individual Oral Health: A Scoping Review. BMC Oral Health, 22.","DOI":"10.1186\/s12903-022-02463-0"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1016\/j.joms.2021.08.122","article-title":"Odontogenic Infections Are More Frequent and More Severe during COVID-19 Pandemic","volume":"79","author":"Drew","year":"2021","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13005-025-00489-7","article-title":"Impact of the COVID-19 Pandemic on Odontogenic Infections in Maxillofacial Surgery","volume":"21","author":"Dudde","year":"2025","journal-title":"Head Face Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13005-023-00381-2","article-title":"The COVID-19 Pandemic and Its Possible Impact on the Treatment of Odontogenic and Intraoral Abscesses","volume":"19","author":"Grill","year":"2023","journal-title":"Head Face Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/s41415-020-1792-3","article-title":"Psychosocial Effects of the COVID-19 Pandemic on Staff in a Dental Teaching Hospital","volume":"229","author":"Mahendran","year":"2020","journal-title":"Br. Dent. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"100025","DOI":"10.1016\/j.adoms.2021.100025","article-title":"The Effect of COVID-19 Outbreak on Hospital Admissions for Dental Infections","volume":"2","author":"Samara","year":"2021","journal-title":"Adv. Oral Maxillofac. Surg."},{"key":"ref_13","first-page":"e61333","article-title":"The Effect of the COVID-19 Pandemic on Odontogenic Cervicofacial Infections in a Single Center in Greece","volume":"16","author":"Louizakis","year":"2024","journal-title":"Cureus"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/adj.12538","article-title":"Clinical Guideline for the Management of Odontogenic Infections in the Tertiary Setting","volume":"62","author":"Vytla","year":"2017","journal-title":"Aust. Dent. J."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Dalewski, B., Palka, L., Kiczmer, P., and Sobolewska, E. (2021). The Impact of SARS-CoV-2 Outbreak on the Polish Dental Community\u2019s Standards of Care\u2014A Six-Month Retrospective Survey-Based Study. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18031281"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Kusumoto, J., Iwata, E., Huang, W., Takata, N., Tachibana, A., and Akashi, M. (2022). Hematologic and Inflammatory Parameters for Determining Severity of Odontogenic Infections at Admission: A Retrospective Study. BMC Infect. Dis., 22.","DOI":"10.1186\/s12879-022-07934-x"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40902-020-00288-x","article-title":"Clinical Utility of Procalcitonin in Severe Odontogenic Maxillofacial Infection","volume":"43","author":"Kim","year":"2021","journal-title":"Maxillofac. Plast. Reconstr. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Hoti, A., Sutej, I., and Jakupi, A. (2025). Impact of the COVID-19 Pandemic on Antibiotic Prescriptions at the University Clinical Dentistry Center of Kosovo. Antibiotics, 14.","DOI":"10.20944\/preprints202501.0509.v1"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"82","DOI":"10.5114\/jhi.2022.117343","article-title":"Clindamycin-Resistant Clostridioides Difficile: A Challenge in Dentistry","volume":"8","author":"Bernatek","year":"2022","journal-title":"J. Health Inequalities"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/iej.12781","article-title":"European Society of Endodontology Position Statement: The Use of Antibiotics in Endodontics","volume":"51","author":"Gould","year":"2018","journal-title":"Int. Endod. J."},{"key":"ref_21","unstructured":"(2025, August 09). GUS Healthcare Expenditure in 2020\u20132022, Available online: https:\/\/stat.gov.pl\/en\/topics\/health\/health\/healthcare-expenditure-in-20202022,18,3.html."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"851","DOI":"10.5114\/aoms.2016.58928","article-title":"Obesity and Inflammation: The Linking Mechanism and the Complications","volume":"13","author":"Ellulu","year":"2017","journal-title":"Arch. Med. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/s41366-021-01035-6","article-title":"Obesity and Infectious Diseases: Pathophysiology and Epidemiology of a Double Pandemic Condition","volume":"46","author":"Pugliese","year":"2022","journal-title":"Int. J. Obes."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"343","DOI":"10.17219\/dmp\/150075","article-title":"Fear and Anxiety of COVID-19 in Dental Patients during the COVID-19 Pandemic: A Cross-Sectional Survey in Turkey","volume":"59","author":"Daltaban","year":"2022","journal-title":"Dent. Med. Probl."},{"key":"ref_25","first-page":"15","article-title":"Patients\u2019 Fear, Stress, and Anxiety Toward Attending Dental Visits During the COVID-19 Pandemic","volume":"96","author":"Nguyen","year":"2022","journal-title":"J. Dent. Hyg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.5114\/jos.2022.122103","article-title":"Evaluation of Access and Attitudes of Patients to Dental Treatments during COVID-19 Pandemic","volume":"75","author":"Alpan","year":"2022","journal-title":"J. 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