{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:37:54Z","timestamp":1780526274901,"version":"3.54.1"},"reference-count":50,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Excessive scarring remains a frequent complication in plastic surgery, yet standardized preventive strategies are lacking. Type I collagen-based biomaterials may support regenerative processes and improve scar outcomes. Methods: This case series includes six female patients (ages 24\u201352) undergoing wound management after trauma and procedures including blepharoplasty, abdominoplasty, and revision mammaplasty. Native collagen type I (7% or 15%) was injected along wound margins or into hypertrophic scars at 3\u20134 week intervals. Outcomes were assessed through patient-reported symptoms and Antera 3D imaging (vascularity, pigmentation, surface topography). Results: Patients reported reduced tightness, pruritus, and scar stiffness after initial sessions. Antera 3D imaging showed decreased vascular and pigment indices, and a reduction in surface elevation over follow-up (up to 14 months). No adverse effects such as atrophy or infection were observed. Conclusions: Native type I collagen was well tolerated and may be a useful adjunct for wound healing and scar modulation following plastic surgery.<\/jats:p>","DOI":"10.3390\/jcm14196989","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T15:07:48Z","timestamp":1759417668000},"page":"6989","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Native Collagen for Surgical Wound and Scar Prevention\u2014A Six-Case Clinical Series"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3651-4703","authenticated-orcid":false,"given":"Olga B.","family":"Borzykh","sequence":"first","affiliation":[{"name":"Plastic Surgery and Cosmetology Clinic \u201cDr. Albrecht\u201d, Voronezh 394036, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena I.","family":"Karpova","sequence":"additional","affiliation":[{"name":"Department of Plastic, Reconstructive Surgery, Cosmetology and Cellular Technologies, Pirogov Russian National Research Medical University, Moscow 119435, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8493-0058","authenticated-orcid":false,"given":"Marina M.","family":"Petrova","sequence":"additional","affiliation":[{"name":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2840-837X","authenticated-orcid":false,"given":"Natalia A.","family":"Shnayder","sequence":"additional","affiliation":[{"name":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"},{"name":"Institute of Personalized Psychiatry and Neurology, Shared Core Facilities, V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, Saint Petersburg 192019, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana V.","family":"Danilova","sequence":"additional","affiliation":[{"name":"Galaktika Clinic, Moscow 121205, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2147\/CCID.S35252","article-title":"Management of keloids and hypertrophic scars: Current and emerging options","volume":"6","author":"Gauglitz","year":"2013","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_2","first-page":"CD011642","article-title":"Laser therapy for treating hypertrophic and keloid scars","volume":"9","author":"Leszczynski","year":"2022","journal-title":"Cochrane Database Syst. 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