{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T07:47:21Z","timestamp":1783151241170,"version":"3.54.6"},"reference-count":49,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:00:00Z","timestamp":1759622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007771","name":"Medical University of Silesia","doi-asserted-by":"publisher","award":["BNW-1-123\/N\/3\/K and BNW-1-180\/K\/4\/K"],"award-info":[{"award-number":["BNW-1-123\/N\/3\/K and BNW-1-180\/K\/4\/K"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Cerebral palsy (CP) is one of the most common causes of permanent motor disability in children, and its consequences for upper limb function have a significant impact on the patient\u2019s independence and quality of life. Virtual reality is attracting increasing interest as a modern, engaging and effective method of physiotherapy for children with cerebral palsy. This systematic literature review aimed to synthesize current scientific data on the impact of virtual-reality-based physiotherapy on upper limb function in children with cerebral palsy. Methods: The review was conducted in accordance with PRISMA 2020 guidelines. PubMed, Science Direct, Scopus, Web of Science, Research Gate and Google Scholar databases were searched for studies published between 2010 and 2025. Six original studies meeting the following criteria were included in the analysis: virtual reality therapy, population of children with cerebral palsy, physiotherapy goals related to the upper limb and availability of full text. Results: All included studies demonstrated a positive impact of virtual reality on at least one functional parameter of the upper limb, including range of motion, muscle strength, coordination and manual precision. Task-oriented training, immersive virtual reality environments and home-based therapy supported by remote monitoring proved to be the most effective. The effects were particularly noticeable in children with moderate impairment at GMFCS I\u2013III. Conclusions: Virtual reality represents a safe and promising technology to support upper limb physiotherapy in children with cerebral palsy. It can be used both in clinical and home settings, contributing to increased exercise intensity and motivation. Further long-term studies using high-quality methodology are needed to determine the sustainability of the effects and their impact on everyday living.<\/jats:p>","DOI":"10.3390\/jcm14197040","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T13:33:41Z","timestamp":1759757621000},"page":"7040","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Impact of Virtual-Reality-Based Physiotherapy on Upper Limb Function in Children with Cerebral Palsy"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0677-3664","authenticated-orcid":false,"given":"Zuzanna","family":"Wojtowicz","sequence":"first","affiliation":[{"name":"Doctoral School, Medical University of Silesia in Katowice, 40-055 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Czech","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-055 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrianna","family":"Lechowska","sequence":"additional","affiliation":[{"name":"Doctoral School, Medical University of Silesia in Katowice, 40-055 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1794-8546","authenticated-orcid":false,"given":"Justyna","family":"Paprocka","sequence":"additional","affiliation":[{"name":"Pediatric Neurology Department, Faculty of Medical Sciences, Medical University of Silesia in Katowice, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,5]]},"reference":[{"key":"ref_1","first-page":"8","article-title":"A report: The definition and classification of cerebral palsy April 2006","volume":"109","author":"Rosenbaum","year":"2007","journal-title":"Dev. Med. Child. Neurol. Suppl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/apa.12614","article-title":"The panorama of cerebral palsy in Sweden. Part XI. Changing patterns in the birth-year period 2003\u20132006","volume":"103","author":"Himmelmann","year":"2014","journal-title":"Acta Paediatr."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.pmr.2009.06.001","article-title":"Cerebral palsy: Classification and epidemiology","volume":"20","author":"Pakula","year":"2009","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/dmcn.12080","article-title":"An update on the prevalence of cerebral palsy: A systematic review and meta-analysis","volume":"55","author":"Oskoui","year":"2013","journal-title":"Dev. Med. Child. Neurol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/09638280500158422","article-title":"The epidemiology of cerebral palsy: Incidence, impairments and risk factors","volume":"28","author":"Odding","year":"2006","journal-title":"Disabil. Rehabil."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/jamapediatrics.2017.1689","article-title":"Early, accurate diagnosis and early intervention in cerebral palsy: Advances in diagnosis and treatment","volume":"171","author":"Novak","year":"2017","journal-title":"JAMA Pediatr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1017\/S0012162206001162","article-title":"The Manual Ability Classification System (MACS) for children with cerebral palsy: Scale development and evidence of validity and reliability","volume":"48","author":"Eliasson","year":"2006","journal-title":"Dev. Med. Child. Neurol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11910-020-1022-z","article-title":"State of the evidence traffic lights 2019: Systematic review of interventions for preventing and treating children with cerebral palsy","volume":"20","author":"Novak","year":"2020","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.physio.2016.08.004","article-title":"Effectiveness of virtual reality rehabilitation for children and adolescents with cerebral palsy: An updated evidence-based systematic review","volume":"103","author":"Ravi","year":"2017","journal-title":"Physiotherapy"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2522\/ptj.20130579","article-title":"Emergence of virtual reality as a tool for upper limb rehabilitation: Incorporation of motor control and motor learning principles","volume":"95","author":"Levin","year":"2015","journal-title":"Phys. Ther."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.chb.2017.01.013","article-title":"A meta-analysis and systematic literature review of virtual reality rehabilitation programs","volume":"70","author":"Howard","year":"2017","journal-title":"Comput. Human. Behav."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/PEP.0000000000000046","article-title":"Effect of virtual reality on upper extremity function in children with cerebral palsy: A meta-analysis","volume":"26","author":"Chen","year":"2014","journal-title":"Pediatr. Phys. Ther."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1080\/09638288.2022.2071484","article-title":"The efficacy of virtual reality interventions compared with conventional physiotherapy in improving the upper limb motor function of children with cerebral palsy: A systematic review of randomised controlled trials","volume":"45","author":"Alrashidi","year":"2023","journal-title":"Disabil. Rehabil."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.bjpt.2020.11.003","article-title":"Effectiveness of virtual reality in children and young adults with cerebral palsy: A systematic review of randomized controlled trials","volume":"25","author":"Fandim","year":"2021","journal-title":"Braz. J. Phys. Ther."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1097\/PHM.0000000000002060","article-title":"Effect of a Virtual Reality-Mediated Gamified Rehabilitation Program on Upper Limb Functions in Children with Hemiplegic Cerebral Palsy: A Prospective, Randomized Controlled Study","volume":"102","author":"Menekseoglu","year":"2023","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1131573","DOI":"10.3389\/fped.2023.1131573","article-title":"Home-based virtual reality-enhanced upper limb training system in children with brain injury: A randomized controlled trial","volume":"11","author":"Choi","year":"2023","journal-title":"Front. Pediatr."},{"key":"ref_17","first-page":"e26085","article-title":"Non-Immersive Virtual Reality as an Intervention for Improving Hand Function and Functional Independence in Children with Unilateral Cerebral Palsy: A Feasibility Study","volume":"14","author":"Goyal","year":"2022","journal-title":"Cureus"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"371","DOI":"10.5606\/tftrd.2019.2388","article-title":"Effect of virtual reality therapy on functional development in children with cerebral palsy: A single-blind, prospective, randomized-controlled study","volume":"65","year":"2019","journal-title":"Turk. J. Phys. Med. Rehabil."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.pediatrneurol.2024.12.001","article-title":"Impact of Virtual Reality Task-Oriented Training on Upper Extremity Motor Function in Children with Cerebral Palsy: A Randomised Controlled Trial","volume":"163","author":"Daliri","year":"2025","journal-title":"Pediatr. Neurol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s12984-023-01218-4","article-title":"Efficacy of integrating a semi-immersive virtual device in the HABIT-ILE intervention for children with unilateral cerebral palsy: A non-inferiority randomized controlled trial","volume":"20","author":"Saussez","year":"2023","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/02692155231187858","article-title":"Effectiveness of virtual reality interventions of the upper limb in children and young adults with cerebral palsy: A systematic review with meta-analysis","volume":"38","author":"Baillet","year":"2024","journal-title":"Clin. Rehabil."},{"key":"ref_22","first-page":"234","article-title":"Upper extremity rehabilitation using Leap Motion controller for children with hemiplegic cerebral palsy: A randomized controlled trial","volume":"34","author":"Avcil","year":"2021","journal-title":"J. Hand Ther."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.apmr.2009.08.153","article-title":"In-home virtual reality videogame telerehabilitation in adolescents with hemiplegic cerebral palsy","volume":"91","author":"Golomb","year":"2010","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/PHM.0000000000002321","article-title":"Effects of nonimmersive virtual reality intervention on children with spastic cerebral palsy: A meta-analysis and systematic review","volume":"102","author":"Wang","year":"2023","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"865474","DOI":"10.3389\/fpubh.2022.865474","article-title":"Effect of virtual reality on balance function in children with cerebral palsy: A systematic review and meta-analysis","volume":"10","author":"Liu","year":"2022","journal-title":"Front. Public Health"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Chang, H.J., Ku, K.H., Park, Y.S., Park, J.G., Cho, E.S., Seo, J.S., Kim, C.W., and Se Hwi, O. (2020). Effects of virtual reality-based rehabilitation on upper extremity function among children with cerebral palsy. Healthcare, 8.","DOI":"10.3390\/healthcare8040391"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"7802180180","DOI":"10.5014\/ajot.2024.050374","article-title":"Effectiveness of virtual reality for upper extremity function and motor performance of children with cerebral palsy: A systematic review","volume":"78","author":"Bell","year":"2024","journal-title":"Am. J. Occup. Ther."},{"key":"ref_28","first-page":"213","article-title":"Virtual reality gaming with physiotherapy improves balance in children with bilateral cerebral palsy: A randomized controlled trial","volume":"14","author":"Jha","year":"2021","journal-title":"J. Pediatr. Rehabil. Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1161\/01.STR.0000162715.43417.91","article-title":"Virtual reality-induced cortical reorganization and associated locomotor recovery in chronic stroke: An experimenter-blind randomized study","volume":"36","author":"You","year":"2005","journal-title":"Stroke"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Tobaiqi, M.A., Albadawi, E.A., Fadlalmola, H.A., and Albadrani, M.S. (2023). Application of Virtual Reality-Assisted Exergaming on the Rehabilitation of Children with Cerebral Palsy: A Systematic Review and Meta-Analysis. J. Clin. Med., 12.","DOI":"10.3390\/jcm12227091"},{"key":"ref_31","first-page":"7937","article-title":"i Ceire, Ureality as a training tool impact on upper extremity function in children with cerebral palsy: A systematic review","volume":"29","author":"Mezaraupa","year":"2024","journal-title":"Educ. Inf. Technol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12984-019-0587-8","article-title":"Learning and transfer of complex motor skills in virtual reality: A perspective review","volume":"16","author":"Levac","year":"2019","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/17518423.2019.1683907","article-title":"Effect of virtual reality therapy on balance and walking in children with cerebral palsy: A systematic review","volume":"23","author":"Warnier","year":"2020","journal-title":"Dev. Neurorehabil."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.2522\/ptj.20060062","article-title":"Use of virtual reality to improve upper-extremity control in children with cerebral palsy: A single-subject design","volume":"87","author":"Chen","year":"2007","journal-title":"Phys. Ther."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e37910","DOI":"10.2196\/38972","article-title":"The effects of virtual reality training on balance, gross motor function, and daily living ability in children with cerebral palsy: Systematic review and meta-analysis","volume":"10","author":"Liu","year":"2022","journal-title":"JMIR Serious Games"},{"key":"ref_36","first-page":"65","article-title":"End-user involvement in rehabilitation virtual reality implementation research","volume":"13","author":"Proffitt","year":"2019","journal-title":"J. Enabling Technol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s40120-012-0003-9","article-title":"Virtual reality versus conventional treatment of reaching ability in chronic stroke: Clinical feasibility study","volume":"1","author":"Levin","year":"2012","journal-title":"Neurol. Ther."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ridd.2013.05.047","article-title":"Precision grip control, sensory impairments and their interactions in children with hemiplegic cerebral palsy: A systematic review","volume":"34","author":"Bleyenheuft","year":"2013","journal-title":"Res. Dev. Disabil."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1177\/0269215514544982","article-title":"Effectiveness of constraint-induced movement therapy on upper-extremity function in children with cerebral palsy: A systematic review and meta-analysis of randomized controlled trials","volume":"28","author":"Chen","year":"2014","journal-title":"Clin. Rehabil."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3109\/17518423.2014.899648","article-title":"Effects of robotic therapy on upper-extremity function in children with cerebral palsy: A systematic review","volume":"19","author":"Chen","year":"2016","journal-title":"Dev. Neurorehabil."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1089\/cpb.2006.9.123","article-title":"Feasibility, motivation, and selective motor control: Virtual reality compared to conventional home exercise in children with cerebral palsy","volume":"9","author":"Bryanton","year":"2006","journal-title":"Cyberpsychol. Behav."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3109\/17518423.2010.501362","article-title":"Interfacing a haptic robotic system with complex virtual environments to treat impaired upper extremity motor function in children with cerebral palsy","volume":"13","author":"Fluet","year":"2010","journal-title":"Dev. Neurorehabil."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3109\/09638288.2011.613520","article-title":"Use of virtual reality in rehabilitation of movement in children with hemiplegia\u2014A multiple case study evaluation","volume":"34","author":"Green","year":"2012","journal-title":"Disabil. Rehabil."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1089\/cpb.2007.0014","article-title":"A low-cost video game applied for training of upper extremity function in children with cerebral palsy: A pilot study","volume":"11","author":"Jannink","year":"2008","journal-title":"Cyberpsychol. Behav."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3233\/TAD-2009-0277","article-title":"The development of a home-based virtual reality therapy system to promote upper extremity movement for children with hemiplegic cerebral palsy","volume":"21","author":"Li","year":"2009","journal-title":"Technol. Disabil."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1743-0003-6-40","article-title":"The New Jersey Institute of Technology Robot-Assisted Virtual Rehabilitation (NJIT-RAVR) system for children with cerebral palsy: A feasibility study","volume":"6","author":"Qiu","year":"2009","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/oti.202","article-title":"The influence of virtual reality on playfulness in children with cerebral palsy: A pilot study","volume":"11","author":"Reid","year":"2004","journal-title":"Occup. Ther. Int."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3233\/TAD-2002-14202","article-title":"The use of virtual reality to improve upper-extremity efficiency skills in children with cerebral palsy: A pilot study","volume":"14","author":"Reid","year":"2002","journal-title":"Technol. Disabil."},{"key":"ref_49","first-page":"255","article-title":"The use of virtual reality with children with cerebral palsy: A pilot randomized trial","volume":"40","author":"Reid","year":"2006","journal-title":"Ther. Recreat. J."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7040\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:21:36Z","timestamp":1760070096000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,5]]},"references-count":49,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["jcm14197040"],"URL":"https:\/\/doi.org\/10.3390\/jcm14197040","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,5]]}}}