{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:02:02Z","timestamp":1774263722233,"version":"3.50.1"},"reference-count":29,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Israel Foundation for Osteoporosis and Bone Diseases"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: This study evaluates the efficacy of a nurse practitioner-managed, computer algorithm-supported institutional fracture liaison service (FLS) that provides treatment recommendations for patients with hip fractures. Methods: A retrospective study included patients hospitalized in the Orthopedic ward with hip fractures between April 1 and October 31. The decision-making algorithm recommends zoledronic acid as the default medication, except for patients younger than 65 years, with estimated glomerular filtration rate (eGFR) &lt;35 or prior osteoporosis therapy, who are ordered to undergo endocrinology consultation. Patients with vitamin D deficiency\/insufficiency are given a loading dose. Results: Two hundred and eight hip fracture patients were identified. The cohort was predominantly female (137\/208, 65.9%); the mean age was 79.9 \u00b1 9.6 years. Nurse practitioner evaluation was performed in 200\/208 patients (96.2%). The algorithm provided a treatment recommendation in 140 out of 200 (70.0%), while 60 out of 200 (30.0%) required an endocrinology consultation. A Vitamin D loading dose was given in 89\/99 (89.9%) deficiency and 44\/62 (71.0%) insufficiency cases. Conclusions: This simplified algorithm-based FLS model demonstrated practicality and feasibility in providing therapeutic recommendations with minimal physician intervention.<\/jats:p>","DOI":"10.3390\/jcm14197062","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T15:05:06Z","timestamp":1759763106000},"page":"7062","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of a Computerized Therapeutic Decision-Making Algorithm in a Fracture Liaison Service Targeting Hip Fracture Patients"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3920-2238","authenticated-orcid":false,"given":"Rachel Chava","family":"Rosenblum","sequence":"first","affiliation":[{"name":"Endocrinology Unit, Wolfson Medical Center, Holon 58100, Israel"},{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Kogan","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Wolfson Medical Center, Holon 58100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Herzberg","sequence":"additional","affiliation":[{"name":"Endocrinology Unit, Wolfson Medical Center, Holon 58100, Israel"},{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maysara","family":"Najjar","sequence":"additional","affiliation":[{"name":"Endocrinology Unit, Wolfson Medical Center, Holon 58100, Israel"},{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2975-9152","authenticated-orcid":false,"given":"Oded","family":"Hershkovich","sequence":"additional","affiliation":[{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"},{"name":"Orthopedic Department, Wolfson Medical Center, Holon 58100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orit","family":"Twito","sequence":"additional","affiliation":[{"name":"Endocrinology Unit, Wolfson Medical Center, Holon 58100, Israel"},{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7968-7906","authenticated-orcid":false,"given":"Raphael","family":"Lotan","sequence":"additional","affiliation":[{"name":"The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel"},{"name":"Orthopedic Department, Wolfson Medical Center, Holon 58100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Str\u00f6m, O., Borgstr\u00f6m, F., Kanis, J.A., Compston, J., Cooper, C., McCloskey, E.V., and J\u00f6nsson, B. 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Int."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7062\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T08:24:53Z","timestamp":1759998293000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,6]]},"references-count":29,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["jcm14197062"],"URL":"https:\/\/doi.org\/10.3390\/jcm14197062","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,6]]}}}