{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T05:23:09Z","timestamp":1777180989073,"version":"3.51.4"},"reference-count":74,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy Cluj-Napoca, Romania, Doctoral Research Program","award":["PCD 647\/41\/11.01.2024"],"award-info":[{"award-number":["PCD 647\/41\/11.01.2024"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Pancreatic and hepatobiliary tumors continue to rank among the deadliest cancers worldwide. Due to a low response rate to treatment, these tumors continue to have a high death rate, a poor prognosis and survival rate, and an overall poor patient outcome. The multimodal strategy used in current treatment includes systemic therapy, radiation therapy, and surgery. However, surgery remains the only treatment with curative intent. Preoperative biliary drainage has a direct impact on the perioperative prognosis of patients with obstructive jaundice and significantly compromised liver function due to hepato-bilio-pancreatic malignancies. Our study\u2019s goal was to determine the safest and most efficient preoperative biliary drainage technique by conducting a systematic review and meta-analysis of resectable periampullary cancers. Methods: Our approach consisted of searching PubMed, BMC Medicine, and Scopus databases using keywords with a result of 1104 articles from 2010 to 2023. The remaining 24 articles that met our inclusion criteria were subjected to meta-analysis using R Commander 4.3.2. Results: Endoscopic retrograde biliary drainage (ERBD) demonstrated a higher rate of postprocedural pancreatitis (RR = 2.22, p &lt; 0.01), intra-abdominal abscess (RR = 1.64, p &lt; 0.01), and delayed gastric emptying (DGE) (RR = 2.07, p &lt; 0.01) than percutaneous transhepatic biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD). Plastic stent (PS) had higher rates of catheter occlusion (RR = 2.20, p &lt; 0.01) and POPF (RR = 1.66, p &lt; 0.01) compared to self-expandable metallic stent (SEMS), which could explain a longer hospital stay (MD = 2.41 days, p &lt; 0.01). However, PS had lower rates of grade 1\u20132 complications (RR = 0.79, p = 0.017) and wound infection rates (RR = 0.66, p = 0.017) than self-expandable metallic stent (SEMS). Conclusions: The choice of a preoperative drainage method can influence postprocedural and postoperative complications rates. ERBD appears to be associated with higher procedure-related and postoperative complication rates and may be linked to a prolonged hospital stay compared to ENBD or PTBD. Moreover, the type of stent placed through ERBD procedure had an important impact on prognosis, as PS had a higher rate of catheter occlusion and POPF, with a prolonged hospital stay compared to SEMS, while mild complications and wound infections were less common in PS group.<\/jats:p>","DOI":"10.3390\/jcm14197097","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T14:06:53Z","timestamp":1759932413000},"page":"7097","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Systematic Review and Meta-Analysis of Preoperative Biliary Drainage Methods in Periampullary Tumors"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0960-9341","authenticated-orcid":false,"given":"Septimiu Alex","family":"Moldovan","sequence":"first","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2972-3777","authenticated-orcid":false,"given":"Emil Ioan","family":"Moi\u0219","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5887-3408","authenticated-orcid":false,"given":"Florin","family":"Graur","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2638-9056","authenticated-orcid":false,"given":"Ion Cosmin","family":"Puia","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iulia","family":"Vlad","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3097-707X","authenticated-orcid":false,"given":"Vlad Ionu\u021b","family":"Nechita","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Medical Informatics and Biostatistics, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Louis Pasteur Str., No. 6, 400349 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lumini\u0163a","family":"Furcea","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9618-9359","authenticated-orcid":false,"given":"Florin","family":"Zaharie","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u0103lin","family":"Popa","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4218-8622","authenticated-orcid":false,"given":"Daniel Corneliu","family":"Leucu\u021ba","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics and Biostatistics, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Louis Pasteur Str., No. 6, 400349 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6318-3826","authenticated-orcid":false,"given":"Simona","family":"Mirel","sequence":"additional","affiliation":[{"name":"Department of Medical Devices, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Louis Pasteur Str., No. 4, 400349 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela \u015etefana","family":"Moldovan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, County Emergency Hospital, Endocrinology Clinic, Louis Pasteur Str., No. 3\u20135, 400349 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7785-6403","authenticated-orcid":false,"given":"Tudor","family":"Mocan","sequence":"additional","affiliation":[{"name":"3rd Medical Department, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 400162 Cluj-Napoca, Romania"},{"name":"UBBMed Department, Babe\u0219-Bolyai University, 400349 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrada","family":"Seicean","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Gastroenterology, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0126-6428","authenticated-orcid":false,"given":"Andra","family":"Ciocan","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadim Al","family":"Hajjar","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u201cOctavian Fodor\u201d Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"},{"name":"Department of Surgery, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Croitorilor Str., No. 19\u201321, 400162 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s10565-019-09465-9","article-title":"Proteomic and Genomic Profiling of Pancreatic Cancer","volume":"35","author":"Ansari","year":"2019","journal-title":"Cell Biol. Toxicol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/SLA.0000000000001763","article-title":"Multi-Institutional Validation Study of the American Joint Commission on Cancer (8th Edition) Changes for T and N Staging in Patients With Pancreatic Adenocarcinoma","volume":"265","author":"Allen","year":"2017","journal-title":"Ann. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e22714","DOI":"10.1097\/MD.0000000000022714","article-title":"The Effect of Preoperative Biliary Stents on Outcomes after Pancreaticoduodenectomy: A Meta-Analysis","volume":"99","author":"Gong","year":"2020","journal-title":"Medicine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12957-020-01848-1","article-title":"Comparison of Effect between Nasobiliary Drainage and Biliary Stenting in Malignant Biliary Obstruction: A Systematic Review and Updated Meta-Analysis","volume":"18","author":"Zhang","year":"2020","journal-title":"World J. Surg. Oncol."},{"key":"ref_5","unstructured":"Basturk, O., Cardin, D.B., Gabriela Chiorean, E., Jared Christensen, F.A., Chung, V., Czito, B., Del Chiaro, M., Donahue, T.R., Fountzilas, C., and Glazer, E.S. (2025). NCCN Guidelines Version 2.2025 Pancreatic Adenocarcinoma, National Comprehensive Cancer Network (NCCN)."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.annonc.2023.08.009","article-title":"Pancreatic Cancer: ESMO Clinical Practice Guideline for Diagnosis, Treatment and Follow-Up\u2606","volume":"34","author":"Conroy","year":"2023","journal-title":"Ann. Oncol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1056\/NEJMoa0903230","article-title":"Preoperative Biliary Drainage for Cancer of the Head of the Pancreas","volume":"362","author":"Rauws","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Zhang, B., Lang, Z., Zhu, K., Luo, W., Zhao, Z., Zhang, Z., and Wang, Z. (2025). Whether Preoperative Biliary Drainage Leads to Better Patient Outcomes of Pancreaticoduodenectomy: A Meta-Analysis and Systematic Review. BMC Gastroenterol., 25.","DOI":"10.1186\/s12876-025-03761-x"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1080\/17474124.2021.2013805","article-title":"Efficacy and Safety of Preoperative Biliary Drainage in Patients Undergoing Pancreaticoduodenectomy: An Updated Systematic Review and Meta-Analysis","volume":"15","author":"Gong","year":"2021","journal-title":"Expert Rev. Gastroenterol. Hepatol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"5386","DOI":"10.3748\/wjg.v23.i29.5386","article-title":"Outcomes of Preoperative Endoscopic Nasobiliary Drainage and Endoscopic Retrograde Biliary Drainage for Malignant Distal Biliary Obstruction Prior to Pancreaticoduodenectomy","volume":"23","author":"Zhang","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3346\/jkms.2012.27.4.356","article-title":"Comparison of Clinical Outcome and Cost-Effectiveness after Various Preoperative Biliary Drainage Methods in Periampullary Cancer with Obstructive Jaundice","volume":"27","author":"Hong","year":"2012","journal-title":"J. Korean Med. Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/MPA.0000000000000265","article-title":"Preoperative Internal Biliary Drainage Increases the Risk of Bile Juice Infection and Pancreatic Fistula after Pancreatoduodenectomy: A Prospective Observational Study","volume":"44","author":"Fujii","year":"2015","journal-title":"Pancreas"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1136\/gutjnl-2014-308762","article-title":"Metal or Plastic Stents for Preoperative Biliary Drainage in Resectable Pancreatic Cancer","volume":"65","author":"Tol","year":"2016","journal-title":"Gut"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/SLE.0b013e3182318d2f","article-title":"What Is Appropriate Procedure for Preoperative Biliary Drainage in Patients with Obstructive Jaundice Awaiting Pancreaticoduodenectomy?","volume":"21","author":"Park","year":"2011","journal-title":"Surg. Laparosc. Endosc. Percutan Tech."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.hpb.2017.12.007","article-title":"Preoperative Biliary Drainage in Resectable Pancreatic Cancer: A Systematic Review and Network Meta-Analysis","volume":"20","author":"Lee","year":"2018","journal-title":"HPB"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1186\/s12957-024-03615-y","article-title":"Goal-Oriented Preoperative Biliary Drainage Is More Precise and Conducive to Seize the Opportunity for Pancreaticoduodenectomy","volume":"22","author":"Cao","year":"2024","journal-title":"World J. Surg. Oncol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"154","DOI":"10.4103\/sjg.sjg_296_23","article-title":"Value of Preoperative Biliary Drainage in Pancreatic Head Cancer Patients with Severe Obstructive Jaundice: A Multicenter Retrospective Study","volume":"30","author":"Lu","year":"2024","journal-title":"Saudi J. Gastroenterol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.gie.2024.03.027","article-title":"American Society for Gastrointestinal Endoscopy Guideline on the Role of Therapeutic EUS in the Management of Biliary Tract Disorders: Summary and Recommendations","volume":"100","author":"Pawa","year":"2024","journal-title":"Gastrointest. Endosc."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00534-007-1277-7","article-title":"Preoperative Biliary Drainage for Biliary Tract and Ampullary Carcinomas","volume":"15","author":"Nagino","year":"2008","journal-title":"J. Hepatobiliary Pancreat. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e5253","DOI":"10.1097\/MD.0000000000005253","article-title":"The Safety and Efficacy of Nasobiliary Drainage versus Biliary Stenting in Malignant Biliary Obstruction","volume":"95","author":"Lin","year":"2016","journal-title":"Medicine"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.4254\/wjh.v7.i18.2171","article-title":"Current Status of Preoperative Drainage for Distal Biliary Obstruction","volume":"7","author":"Sugiyama","year":"2015","journal-title":"World J. Hepatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/gastro\/gou083","article-title":"Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis","volume":"3","author":"Thaker","year":"2015","journal-title":"Gastroenterol. Rep."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Classification of Acute Pancreatitis\u20142012: Revision of the Atlanta Classification and Definitions by International Consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/jhbp.512","article-title":"Tokyo Guidelines 2018: Diagnostic Criteria and Severity Grading of Acute Cholangitis (with Videos)","volume":"25","author":"Kiriyama","year":"2018","journal-title":"J. Hepatobiliary Pancreat. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.gie.2011.07.010","article-title":"Complications of ERCP","volume":"75","author":"Anderson","year":"2012","journal-title":"Gastrointest. Endosc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.gie.2016.06.051","article-title":"Adverse Events Associated with ERCP","volume":"85","author":"Chandrasekhara","year":"2017","journal-title":"Gastrointest. Endosc."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 Update of the International Study Group (ISGPS) Definition and Grading of Postoperative Pancreatic Fistula: 11 Years After","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of Surgical Complications","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00134-019-05841-5","article-title":"Post-Operative Abdominal Infections: Epidemiology, Operational Definitions, and Outcomes","volume":"46","author":"Bassetti","year":"2020","journal-title":"Intensive Care Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.surg.2007.02.001","article-title":"Postpancreatectomy Hemorrhage (PPH)\u2013An International Study Group of Pancreatic Surgery (ISGPS) Definition","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.surg.2016.06.058","article-title":"Definition and Classification of Chyle Leak after Pancreatic Operation: A Consensus Statement by the International Study Group on Pancreatic Surgery","volume":"161","author":"Besselink","year":"2017","journal-title":"Surgery"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.surg.2010.12.002","article-title":"Bile Leakage after Hepatobiliary and Pancreatic Surgery: A Definition and Grading of Severity by the International Study Group of Liver Surgery","volume":"149","author":"Koch","year":"2011","journal-title":"Surgery"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.surg.2007.05.005","article-title":"Delayed Gastric Emptying (DGE) after Pancreatic Surgery: A Suggested Definition by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Wan, X., Wang, W., Liu, J., and Tong, T. (2014). Estimating the Sample Mean and Standard Deviation from the Sample Size, Median, Range and\/or Interquartile Range. BMC Med. Res. Methodol., 14.","DOI":"10.1186\/1471-2288-14-135"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1177\/0962280216669183","article-title":"Optimally Estimating the Sample Mean from the Sample Size, Median, Mid-Range, and\/or Mid-Quartile Range","volume":"27","author":"Luo","year":"2018","journal-title":"Stat. Methods Med. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/00015458.2021.1920659","article-title":"Impact of Biliary Drainage Prior to Pancreatectomy","volume":"122","author":"Bademci","year":"2022","journal-title":"Acta Chir. Belg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"391","DOI":"10.21873\/invivo.12716","article-title":"The Optimal Type and Management of Biliary Drainage in Patients With Obstructive Jaundice Who Undergo Pancreaticoduodenectomy","volume":"36","author":"Satoh","year":"2022","journal-title":"In Vivo"},{"key":"ref_39","first-page":"403","article-title":"Effects of Preoperative Biliary Drainage Methods and Time to Postoperative Complications after Biliary Drainage in Periampullary Tumors","volume":"93","author":"Subasi","year":"2022","journal-title":"Ann. Ital. Chir."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.hpb.2020.06.009","article-title":"Nationwide Practice and Outcomes of Endoscopic Biliary Drainage in Resectable Pancreatic Head and Periampullary Cancer","volume":"23","author":"Latenstein","year":"2021","journal-title":"HPB"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.21037\/gs-20-711","article-title":"Preoperative Endoscopic Retrograde Biliary Drainage Increases Postoperative Complications after Pancreaticoduodenectomy Compared to Endoscopic Nasobiliary Drainage","volume":"10","author":"Han","year":"2021","journal-title":"Gland Surg."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e723","DOI":"10.1097\/MD.0000000000000723","article-title":"The Effects of Different Preoperative Biliary Drainage Methods on Complications Following Pancreaticoduodenectomy","volume":"94","author":"Huang","year":"2015","journal-title":"Medicine"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1177\/1457496914543975","article-title":"Preoperative Biliary Decompression Preceding Pancreaticoduodenectomy with Plastic or Self-Expandable Metallic Stent","volume":"104","author":"Udd","year":"2015","journal-title":"Scand. J. Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"6847","DOI":"10.3748\/wjg.v25.i47.6847","article-title":"Influence of Bile Contamination for Patients Who Undergo Pancreaticoduodenectomy after Biliary Drainage","volume":"25","author":"Okano","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1111\/ans.17060","article-title":"Metal Stents Are Safe and Cost-effective for Preoperative Biliary Drainage in Resectable Pancreaticobiliary Tumours","volume":"91","author":"Roberts","year":"2021","journal-title":"ANZ J. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/jhbp.529","article-title":"Preoperative Biliary Drainage Adversely Affects Surgical Outcomes in Periampullary Cancer: A Retrospective and Propensity Score-Matched Analysis","volume":"25","author":"Lee","year":"2018","journal-title":"J. Hepatobiliary Pancreat. Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"E363","DOI":"10.1111\/ans.15329","article-title":"Impact of Preoperative Percutaneous Transhepatic Biliary Drainage on Post-Operative Survival in Patients with Distal Cholangiocarcinoma","volume":"89","author":"Mori","year":"2019","journal-title":"ANZ J. Surg."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.hpb.2020.06.005","article-title":"Adverse Oncologic Effects of Preoperative Biliary Drainage on Early Stage Ampulla of Vater Cancer","volume":"23","author":"Byun","year":"2021","journal-title":"HPB"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.amjsurg.2013.10.021","article-title":"Preoperative Cholangitis during Biliary Drainage Increases the Incidence of Postoperative Severe Complications after Pancreaticoduodenectomy","volume":"208","author":"Kitahata","year":"2014","journal-title":"Am. J. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"106043","DOI":"10.1016\/j.ijsu.2021.106043","article-title":"Endoscopic versus Percutaneous Biliary Drainage for Resectable Pancreatic Head Cancer with Hyperbilirubinemia and Impact on Pancreaticoduodenectomy: A Randomized Controlled Study","volume":"93","author":"Sabry","year":"2021","journal-title":"Int. J. Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/jhbp.811","article-title":"A Multicenter Prospective Randomized Controlled Trial for Preoperative Biliary Drainage with Uncovered Metal versus Plastic Stents for Resectable Periampullary Cancer","volume":"27","author":"Cho","year":"2020","journal-title":"J. Hepatobiliary Pancreat. Sci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1038\/ajg.2013.93","article-title":"Biliary Self-Expandable Metal Stents Do Not Adversely Affect Pancreaticoduodenectomy","volume":"108","author":"Cavell","year":"2013","journal-title":"Am. J. Gastroenterol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1245\/s10434-020-08645-w","article-title":"Impact of Qualitative and Quantitative Biliary Contamination Status on the Incidence of Postoperative Infection Complications in Patients Undergoing Pancreatoduodenectomy","volume":"28","author":"Suenaga","year":"2021","journal-title":"Ann. Surg. Oncol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1245\/s10434-015-4618-9","article-title":"Impact of Preoperative Biliary Drainage on Long-Term Survival in Resected Pancreatic Ductal Adenocarcinoma: A Multicenter Observational Study","volume":"22","author":"Uemura","year":"2015","journal-title":"Ann. Surg. Oncol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.gie.2016.04.018","article-title":"Metal versus Plastic Stents for Drainage of Malignant Biliary Obstruction before Primary Surgical Resection","volume":"84","author":"Song","year":"2016","journal-title":"Gastrointest. Endosc."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"269","DOI":"10.5009\/gnl18573","article-title":"Clinical Outcomes of Biliary Drainage during a Neoadjuvant Therapy for Pancreatic Cancer: Metal versus Plastic Stents","volume":"14","author":"Kuwatani","year":"2020","journal-title":"Gut Liver"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.3748\/wjg.v22.i14.3793","article-title":"Multicenter Study of Endoscopic Preoperative Biliary Drainage for Malignant Distal Biliary Obstruction","volume":"22","author":"Sasahira","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1002\/bjs.7228","article-title":"Percutaneous Transhepatic Biliary Drainage Catheter Tract Recurrence in Cholangiocarcinoma","volume":"97","author":"Takahashi","year":"2010","journal-title":"Br. J. Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/MCG.0b013e318272440e","article-title":"Effect of Endoscopic Stenting of Malignant Bile Duct Obstruction on Quality of Life","volume":"47","author":"Barkay","year":"2013","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1572-0241.2006.00380.x","article-title":"Risk Factors for Post-ERCP Pancreatitis: A Prospective Multicenter Study","volume":"101","author":"Cheng","year":"2006","journal-title":"Am. J. Gastroenterol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.gie.2010.05.023","article-title":"Risk of Post-ERCP Pancreatitis with Placement of Self-Expandable Metallic Stents","volume":"72","author":"Kumar","year":"2010","journal-title":"Gastrointest. Endosc."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jamcollsurg.2005.09.006","article-title":"Effect of Bile Contamination on Immediate Outcomes after Pancreaticoduodenectomy for Tumor","volume":"202","author":"Cortes","year":"2006","journal-title":"J. Am. Coll. Surg."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"7797","DOI":"10.3748\/wjg.v22.i34.7797","article-title":"Risk Factors for Postoperative Pancreatic Fistula: Analysis of 539 Successive Cases of Pancreaticoduodenectomy","volume":"22","author":"Hu","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"752","DOI":"10.5114\/aoms.2020.94160","article-title":"Internal Drainage versus External Drainage in Palliation of Malignant Biliary Obstruction: A Meta-Analysis and Systematic Review","volume":"16","author":"Tian","year":"2020","journal-title":"Arch. Med. Sci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jvir.2017.12.027","article-title":"Is Percutaneous Transhepatic Biliary Drainage Better than Endoscopic Drainage in the Management of Jaundiced Patients Awaiting Pancreaticoduodenectomy? A Systematic Review and Meta-Analysis","volume":"29","author":"Dorcaratto","year":"2018","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s40644-017-0129-1","article-title":"Comparison of Efficacy and Complications of Endoscopic and Percutaneous Biliary Drainage in Malignant Obstructive Jaundice: A Systematic Review and Meta-Analysis","volume":"17","author":"Duan","year":"2017","journal-title":"Cancer Imaging"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.gie.2021.09.010","article-title":"Comparative Efficacy of Different Methods for Difficult Biliary Cannulation in ERCP: Systematic Review and Network Meta-Analysis","volume":"95","author":"Facciorusso","year":"2022","journal-title":"Gastrointest. Endosc."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00595-017-1568-9","article-title":"Effectiveness and Risk of Biliary Drainage Prior to Pancreatoduodenectomy: Review of Current Status","volume":"48","author":"Fuks","year":"2018","journal-title":"Surg. Today"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jso.23797","article-title":"Does Preoperative Biliary Drainage Compromise the Long-Term Survival of Patients with Pancreatic Head Carcinoma?","volume":"111","author":"Murakami","year":"2015","journal-title":"J. Surg. Oncol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1007\/s00464-015-4075-3","article-title":"Comparative Long-Term Outcomes of Upfront Resected Pancreatic Cancer after Preoperative Biliary Drainage","volume":"29","author":"Strom","year":"2015","journal-title":"Surg. Endosc."},{"key":"ref_71","first-page":"1274","article-title":"Association of Preoperative Obstructive Jaundice with Postoperative Infectious Complications Following Pancreaticoduodenectomy","volume":"60","author":"Wang","year":"2013","journal-title":"Hepatogastroenterology"},{"key":"ref_72","first-page":"24","article-title":"Relationship of Postoperative Complications from Preoperative Biliary Stents after Pancreaticoduodenectomy. A New Cohort Analysis and Meta-Analysis of Modern Studies","volume":"10","author":"Velanovich","year":"2009","journal-title":"JOP"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.surge.2014.02.004","article-title":"The Current Status of Preoperative Biliary Drainage for Patients Who Receive Pancreaticoduodenectomy for Periampullary Carcinoma: A Comprehensive Review","volume":"12","author":"Lai","year":"2014","journal-title":"Surgeon"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.gie.2016.02.047","article-title":"Cost-Effectiveness and Clinical Efficacy of Biliary Stents in Patients Undergoing Neoadjuvant Therapy for Pancreatic Adenocarcinoma in a Randomized Controlled Trial","volume":"84","author":"Gardner","year":"2016","journal-title":"Gastrointest. Endosc."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7097\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:50:37Z","timestamp":1760035837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/19\/7097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,8]]},"references-count":74,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["jcm14197097"],"URL":"https:\/\/doi.org\/10.3390\/jcm14197097","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,8]]}}}