{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:10:33Z","timestamp":1787508633665,"version":"build-2736575974"},"reference-count":30,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Vascular closure of the femoral artery during transcatheter aortic valve implantation (TAVI) remains a critical step prone to complications, despite advancements in introducer technology. The traditional technique involves using two ProGlide\u00ae suture closure devices (2P), but alternative approaches, such as employing a single ProGlide\u00ae device (1P), have emerged. Aims: We sought to evaluate the efficacy and safety of the 1P strategy compared to the standard 2P closure technique during transfemoral TAVI procedures. Methods: A registry-based study was conducted at the University Hospitals of Strasbourg, France, from January 2020 to December 2023. Consecutive patients who underwent TAVI via the transfemoral approach were deemed eligible. Results: The study cohort consisted of 1303 patients, with a mean age of 81.7 years and 47% female. The 1P strategy was used in 733 cases (56.3%), while the 2P technique was employed in 570 patients (43.7%). Hemostasis was achieved in the catheterization laboratory without additional devices in 30.4% of the single-ProGlide\u00ae pre-closing cases. Vascular complication rates were similar in both groups, at 11.3% for the 1P technique and 11.4% for the 2P technique (p = 0.964). However, vascular closure device failure was significantly less frequent in the 1P group (1.6%) compared to the 2P group (5.3%). Conclusions: The 1P strategy for pre-closing during TAVI is as effective and safe as the conventional 2P approach. The 1P method offers potential advantages in terms of simplicity and cost-effectiveness.<\/jats:p>","DOI":"10.3390\/jcm14197113","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:19:26Z","timestamp":1760015966000},"page":"7113","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Femoral Closure with Single ProGlide\u00ae in Transcatheter Aortic Valve Implantation: A Registry-Based Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2581-577X","authenticated-orcid":false,"given":"K\u00e9vin","family":"Roulot","sequence":"first","affiliation":[{"name":"Service de Cardiologie and Service de Chirurgie Cardio-Vasculaire, P\u00f4le d\u2019Activit\u00e9 Medico-Chirurgicale, Nouvel Hopital Civil, 67000 Strasbourg, Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Kibler","sequence":"additional","affiliation":[{"name":"Service de Cardiologie and Service de Chirurgie Cardio-Vasculaire, P\u00f4le d\u2019Activit\u00e9 Medico-Chirurgicale, Nouvel Hopital Civil, 67000 Strasbourg, Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9279-4220","authenticated-orcid":false,"given":"Antonin","family":"Trimaille","sequence":"additional","affiliation":[{"name":"Service de Cardiologie and Service de Chirurgie Cardio-Vasculaire, P\u00f4le d\u2019Activit\u00e9 Medico-Chirurgicale, Nouvel Hopital Civil, 67000 Strasbourg, Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3477-208X","authenticated-orcid":false,"given":"Adrien","family":"Carmona","sequence":"additional","affiliation":[{"name":"Service de Cardiologie and Service de Chirurgie Cardio-Vasculaire, 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