{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:42:02Z","timestamp":1760575322566,"version":"build-2065373602"},"reference-count":51,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Chronic low back pain is often associated with impaired balance and reduced functional mobility. Recent studies suggest that virtual reality-based interventions may be effective in improving balance outcomes in individuals with chronic low back pain. Objective: In this systematic review and meta-analysis, we aimed to investigate the impact of virtual reality training on static and dynamic balance outcomes in patients with chronic low back pain. Methods: Two independent reviewers searched English-language studies from inception to 1 July 2024, using the following databases: PubMed, Web of Science, Scopus, Dimensions, Semantic Scholar, and ProQuest. Randomized clinical trials with a PEDro score of \u22656 were included. Fixed- and random-effects meta-analyses were conducted on eligible trials. Results: Of 3172 records screened, 13 trials were eligible. Meta-analyses of six trials (n = 183) across diverse adults using 2\u20138 week interventions showed that virtual reality training improved dynamic balance: timed up and go (mean difference: \u22122.29 s; 95% confidence interval: \u22122.91 to \u22121.66; I2 = 0%; p &lt; 0.00001) and forward reach (mean difference: 7.80 cm; 95% confidence interval: 2.08 to 13.52; I2 = 0%; p = 0.008). However, no significant effects were found for static balance, single-leg stance, center of pressure medio-lateral displacement, or center of pressure velocity, compared with controls. Conclusions: Virtual reality-based training seems to be more effective than control interventions in improving dynamic and functional balance, but not static balance, in patients with chronic low back pain.<\/jats:p>","DOI":"10.3390\/jcm14207247","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T11:57:42Z","timestamp":1760529462000},"page":"7247","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Virtual Reality Training for Balance in Patients with Chronic Low Back Pain: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"14","author":[{"given":"Abrar I.","family":"AlSadiq","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Dammam Medical Complex, Dammam 32253, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuad A.","family":"Abdulla","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Allied Medical Sciences, Philadelphia University, Amman 19392, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3263-8896","authenticated-orcid":false,"given":"Ali M.","family":"Alshami","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1001\/archinternmed.2008.543","article-title":"The rising prevalence of chronic low back pain","volume":"169","author":"Freburger","year":"2009","journal-title":"Arch. 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