{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:43:20Z","timestamp":1768481000926,"version":"3.49.0"},"reference-count":14,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Spinal epidural abscess (SEA) is a rare but challenging disease. Hyperbaric oxygen therapy (HBOT) is used as an adjunctive therapy for SEA in a limited number of hospitals; however, its efficacy has not been well described. Case: A 70-year-old man presented at our hospital with cervical pain, fever, and impaired right shoulder movement. The patient fell after drinking 17 days prior to the presentation. He was diagnosed with an SEA secondary to a spinal epidural hematoma caused by a prior injury. The patient also had dental caries, and his blood culture was positive for Streptococcus intermedius. We diagnosed the patient with a spinal epidural abscess and hematoma that developed from the caries and the injury. Antibiotics were initiated; however, the motor function gradually worsened, and decompressive surgery was performed. After surgery, neurological impairment persisted, and HBOT was used as an adjunctive therapy. After initiating HBOT, the patient\u2019s arm movements improved, and he was referred to a rehabilitation hospital on day 110 for further rehabilitation. Conclusions: HBOT is increasingly used for spinal cord infections and injuries in a limited number of institutions. It is a potentially effective adjunctive therapy for patients for whom antibiotics and surgery are ineffective.<\/jats:p>","DOI":"10.3390\/jcm14207346","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T11:39:34Z","timestamp":1760701174000},"page":"7346","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cervical Epidural Abscess Secondary to a Post-Traumatic Hematoma, Successfully Treated with Adjunctive Hyperbaric Oxygen Therapy: A Case Report"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7054-8448","authenticated-orcid":false,"given":"Yoshiaki","family":"Iwashita","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naho","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Mukoyama","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Kodani","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, School of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6004-1371","authenticated-orcid":false,"given":"Tetsuya","family":"Makiishi","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Faculty of Medicine, Shimane University, Izumo 693-8501, Shimane, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1056\/NEJMra055111","article-title":"Spinal Epidural Abscess","volume":"355","author":"Darouiche","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"ref_2","first-page":"1341","article-title":"Spinal Epidural Abscess: A Diagnostic Challenge","volume":"65","author":"Chao","year":"2002","journal-title":"Am. Fam. Physician"},{"key":"ref_3","first-page":"e621","article-title":"Delayed Presentation of a Cervical Spinal Epidural Abscess of Dental Origin after a Fall in an Elderly Patient","volume":"8","author":"Bodman","year":"2016","journal-title":"Cureus"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/1793-5482.151527","article-title":"Infected Epidural Hematoma of the Lumbar Spine Associated with Invasive Pneumococcal Disease","volume":"10","author":"Inamasu","year":"2015","journal-title":"Asian J. Neurosurg."},{"key":"ref_5","unstructured":"Moon, R.E. (2019). Hyperbaric Oxygen Therapy Indications, Undersea & Hyperbaric Medical Society. [14th ed.]."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.21037\/jss.2017.05.04","article-title":"Streptococcus intermedius: An Unusual Cause of Spinal Epidural Abscess","volume":"3","author":"Ramhmdani","year":"2017","journal-title":"J. Spine Surg."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Liu, D., Lu, W., Huang, W., Zhai, W., and Ling, Q. (2023). Extensive Spinal Epidural Abscess Due to Streptococcus intermedius: A Case Report Treated Conservatively and Literature Review. Front. Neurol., 14.","DOI":"10.3389\/fneur.2023.1237007"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/FS9.0000000000000084","article-title":"Early decompressive surgery within 72 hours of admission maintains financial advantages for patients with spinal epidural abscess, as evidenced by a retrospective study involving 130 cases","volume":"57","author":"Yang","year":"2024","journal-title":"Formos. J. Surg."},{"key":"ref_9","first-page":"381","article-title":"Successful Treatment of Cervical Spinal Epidural Abscess by Combined Hyperbaric Oxygenation","volume":"72","author":"Kohshi","year":"2005","journal-title":"Mt. Sinai J. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.surneu.2006.12.047","article-title":"Successful Treatment of Extended Epidural Abscess and Long Segment Osteomyelitis: A Case Report and Review of the Literature","volume":"69","author":"Chang","year":"2008","journal-title":"Surg. Neurol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000121383","article-title":"Hyperbaric Oxygen Therapy for the Treatment of an Epidural Abscess in the Posterior Fossa in an 8-Month-Old Infant","volume":"44","author":"Baechli","year":"2008","journal-title":"Pediatr. Neurosurg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/s12974-023-02985-6","article-title":"Oxygen Therapy Attenuates Neuroinflammation after Spinal Cord Injury","volume":"20","author":"Sunshine","year":"2023","journal-title":"J. Neuroinflamm."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"905","DOI":"10.3233\/BMR-200157","article-title":"Effects of Hyperbaric Oxygen Therapy on Patients with Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","volume":"34","author":"Huang","year":"2021","journal-title":"J. Back Musculoskelet. Rehabil."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/sj.sc.3101023","article-title":"Hyperbaric Oxygen Therapy for Acute Traumatic Cervical Spinal Cord Injury","volume":"38","author":"Asamoto","year":"2000","journal-title":"Spinal Cord"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/20\/7346\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:20:48Z","timestamp":1760703648000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/20\/7346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,17]]},"references-count":14,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["jcm14207346"],"URL":"https:\/\/doi.org\/10.3390\/jcm14207346","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,17]]}}}