{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:28:04Z","timestamp":1791912484712,"version":"4.3.4"},"reference-count":61,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003718","name":"Korea Institute of Oriental Medicine","doi-asserted-by":"publisher","award":["KSN2511012"],"award-info":[{"award-number":["KSN2511012"]}],"id":[{"id":"10.13039\/501100003718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["RS-2020-KH088006"],"award-info":[{"award-number":["RS-2020-KH088006"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Activities of daily living (ADL) are critical for independence after stroke, yet many survivors remain functionally limited. Vibration therapy (VT), including whole-body and focal modalities, has been proposed as an adjunct to enhance recovery, but effects on ADL remain unclear. This study aimed to evaluate the overall effectiveness of VT on ADL and to identify moderating factors. Methods: A systematic review and meta-analysis were conducted following PRISMA 2020 guidelines. Thirteen controlled trials (12 RCTs, 1 nRCT) involving VT in stroke were included. Standardized mean differences (Hedges\u2019 g) were synthesized using random-effects models. Meta-regression and subgroup analyses examined moderators such as session number, vibration parameters, stroke stage, and ADL subdomains. Risk of bias was assessed with RoB 2 and ROBINS-I. Results: VT produced a small but significant effect on ADL (Hedges\u2019 g = 0.19; 95% CI: 0.06\u20130.33; p = 0.008), though significance was lost after adjustment for publication bias. Heterogeneity was moderate (I2 = 34%). Session number was the only significant moderator (p = 0.045), explaining ~24% of variance, with the greatest benefit in the 13\u201324 session range (g = 0.34; 95% CI: 0.05\u20130.63). Subgroup analysis showed improvement in physical function\/mobility (g = 0.32; p = 0.048), but not in self-care or quality-of-life outcomes. Other parameters were not significant moderators. Conclusions: VT confers modest benefits for ADL after stroke, particularly in mobility-related domains. Session number appears clinically important, with 13\u201324 sessions suggesting an optimal dose window.<\/jats:p>","DOI":"10.3390\/jcm14217682","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T03:44:39Z","timestamp":1761795879000},"page":"7682","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effects of Vibration Therapy on Activities of Daily Living After Stroke: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2661-349X","authenticated-orcid":false,"given":"Jeong-Woo","family":"Seo","sequence":"first","affiliation":[{"name":"Digital Health Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0408-5569","authenticated-orcid":false,"given":"Jaeuk. U.","family":"Kim","sequence":"additional","affiliation":[{"name":"Digital Health Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7939-2278","authenticated-orcid":false,"given":"Jung-Dae","family":"Kim","sequence":"additional","affiliation":[{"name":"Digital Health Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Woo","family":"Seok","sequence":"additional","affiliation":[{"name":"Digital Health Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1001\/jama.1963.03060120024016","article-title":"Studies of Illness in the Aged: The Index of ADL: A Standardized Measure of Biological and Psychosocial Function","volume":"185","author":"Katz","year":"1963","journal-title":"JAMA"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1161\/STROKEAHA.110.604090","article-title":"Early Prediction of Outcome of Activities of Daily Living after Stroke: A Systematic Review","volume":"42","author":"Veerbeek","year":"2011","journal-title":"Stroke"},{"key":"ref_3","first-page":"707","article-title":"Understanding Upper Limb Recovery after Stroke","volume":"31","author":"Kwakkel","year":"2013","journal-title":"Restor. 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