{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T13:09:50Z","timestamp":1762261790133,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objective: Ventricular septal defect (VSD) is the most common congenital heart anomaly, with the perimembranous subtype (pmVSD) being among the most prevalent forms. Surgical repair remains the gold standard for treatment; however, percutaneous closure has emerged as a promising alternative due to the availability of various occlusion devices. Each technique presents distinct advantages and limitations, particularly in terms of complications and long-term outcomes. We sought to evaluate the safety and mid-term outcomes of pmVSD closure employing the Nit-Occlud\u00ae Le VSD Coil within a single-centre, single-team setting. Methods: Of the 55 patients hospitalised for pmVSD closure, 45 children underwent the procedure with the Nit-Occlud\u00ae Le VSD device. Relevant clinical and defect-related data were collected during hospitalisation and throughout follow-up. Results: Among 45 patients, successful coil implantation was achieved in 41 cases (91.1%). Periprocedural complications occurred in 8 patients (17.8%), including haemolysis, transient atrioventricular block, aortic valve injury, transient ST-segment elevation and supraventricular tachycardia. Two of these complications (4.4%) were classified as severe. The occurrence of complications was significantly associated with the type of VSD shunt (p = 0.03). Conclusions: Transcatheter closure of pmVSD using the Nit-Occlud\u00ae L\u00ea VSD Coil in young children is a feasible and safe option with careful patient selection. Patients with type C pmVSD appear to benefit the most. Nevertheless, potential complications, including haemolysis and aortic valve injury, require close monitoring.<\/jats:p>","DOI":"10.3390\/jcm14217822","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T12:13:08Z","timestamp":1762258388000},"page":"7822","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the Safety and Efficacy of Transcatheter Closure of Perimembranous Ventricular Septal Defects with a Single Device Type: A Single-Centre Experience"],"prefix":"10.3390","volume":"14","author":[{"given":"Piotr","family":"Wery\u0144ski","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Pediatric Gastroenterology with Pediatric Cardiology Subdivision, St. Jadwiga the Queen Clinical Regional Hospital No. 2, 35-301 Rzesz\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3260-8846","authenticated-orcid":false,"given":"Oksana","family":"Tr\u0119bacz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Pediatric Gastroenterology with Pediatric Cardiology Subdivision, St. Jadwiga the Queen Clinical Regional Hospital No. 2, 35-301 Rzesz\u00f3w, Poland"},{"name":"Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Science, 31-343 Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Tara\u0142a","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Pediatric Gastroenterology with Pediatric Cardiology Subdivision, St. Jadwiga the Queen Clinical Regional Hospital No. 2, 35-301 Rzesz\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrycja","family":"Florek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Pediatric Gastroenterology with Pediatric Cardiology Subdivision, St. Jadwiga the Queen Clinical Regional Hospital No. 2, 35-301 Rzesz\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Podlewski","sequence":"additional","affiliation":[{"name":"Dover Fueling Solutions, 30-320 Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Sabiniewicz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Congenital Heart Diseases, Medical University of Gdansk, 80-211 Gdansk, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S0140-6736(10)61339-6","article-title":"Ventricular septal defect","volume":"377","author":"Penny","year":"2011","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J. 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