{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T05:21:24Z","timestamp":1762665684727,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010438","name":"Poznan University of Medical Sciences","doi-asserted-by":"crossref","award":["502-20-22073190"],"award-info":[{"award-number":["502-20-22073190"]}],"id":[{"id":"10.13039\/501100010438","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: Dental eruption is a complex process influenced by various factors, including endocrine factors as growth hormone (GH). The aim of this study was to assess differences in the advancement of tooth eruption between growth hormone-deficient (GHD) and idiopathic short-statured (ISS) children and a control group of children with normal growth patterns. Methods: A total of 156 children participated in this study: 78 patients with short stature (50 boys and 28 girls) and 78 healthy and age- and sex-matched control subjects. Each permanent tooth was classified according to its clinical eruption stage by one trained and calibrated dentist. Results: The mean age was 10.22 \u00b1 2.42 years for the study and 10.15 \u00b1 2.45 for the control group. In our study, we observed eruption delay during the early mixed dentition stage. A significant difference was found in the degree of eruption for all incisors and first permanent molars between the GHD before treatment group and the control group (p = 0.045). The difference was apparent at the initial stage of permanent tooth eruption, in the group of children who had not yet initiated growth hormone treatment. The eruption of remaining tooth groups did not differ significantly between the children with growth failure and the control group (p &gt; 0.05). Conclusions: Our findings indicate that the delay in tooth eruption observed in short-statured children, particularly affecting the first permanent molars and incisors, may reflect the direct influence of growth hormone deficiency on early dental development. The clinical relevance of this finding underlines the importance of individualized dental care and careful timing of orthodontic assessments in short-statured patients, especially prior to the initiation of GH therapy.<\/jats:p>","DOI":"10.3390\/jcm14227896","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T11:41:47Z","timestamp":1762515707000},"page":"7896","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Variability in Permanent Teeth Eruption in Children with Growth Hormone Deficiency and Idiopathic Short Stature"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4761-737X","authenticated-orcid":false,"given":"Natalia","family":"Torli\u0144ska-Walkowiak","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5319-5057","authenticated-orcid":false,"given":"Anna","family":"Sowi\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Statistics, Poznan University of Medical Sciences, 60-806 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3573-2274","authenticated-orcid":false,"given":"Katarzyna Anna","family":"Majewska","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diabetes, Auxology and Obesity, Poznan University of Medical Sciences, 60-572 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8206-6094","authenticated-orcid":false,"given":"Andrzej","family":"K\u0119dzia","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diabetes, Auxology and Obesity, Poznan University of Medical Sciences, 60-572 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5091-3316","authenticated-orcid":false,"given":"Justyna","family":"Opydo-Szymaczek","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1365-263X.2011.01114.x","article-title":"A prospective cohort study on emergence of permanent teeth and caries experience in Korean children","volume":"21","author":"Kim","year":"2011","journal-title":"Int. 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