{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T05:21:27Z","timestamp":1764220887526,"version":"3.46.0"},"reference-count":48,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Acute coronary syndrome is the primary reason for admission to cardiology services and involves significant resource consumption. Currently, low-risk patients are recommended for discharge within the first 48\u201372 h, enabling early initiation of cardiac rehabilitation with proper follow-up. This is crucial not only as an efficiency marker but also because current evidence has shown it to be a safe and feasible strategy. Thus, this work aims to provide a comprehensive review of the current evidence on early discharge in acute coronary syndrome and propose a new, intuitive, objective, and easy-to-use tool: the LATE2ACS protocol. This is a narrative, hypothesis-generating review; LATE2ACS is presented as a preliminary, exploratory checklist rather than a definitive or implementable score. Its added value lies in operationalizing post-PCI early discharge decision-making across ACS as a pragmatic bedside checklist that complements, rather than replaces, prognostic scores such as TIMI, GRACE, Zwolle, and CADILLAC.<\/jats:p>","DOI":"10.3390\/jcm14238373","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T17:31:34Z","timestamp":1764091894000},"page":"8373","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Protocol for Feasibility and Safety in Early Discharge with ACS"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4181-6914","authenticated-orcid":false,"given":"Karim","family":"Jamhour-Chelh","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit, Cardiology Department, Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0735-1097(88)90160-X","article-title":"Importance of clinical measures of ischemia in the prognosis of patients with documented coronary artery disease","volume":"11","author":"Califf","year":"1988","journal-title":"J. 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