{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T09:56:15Z","timestamp":1774432575849,"version":"3.50.1"},"reference-count":71,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Cardiomyopathies, including hypertrophic (HCM), dilated (DCM), and arrhythmogenic (ACM) forms, represent a challenge in cardiovascular medicine, in particular regarding exercise participation and cardiac rehabilitation. Traditionally, physical activity was restricted in these patients due to concerns over arrhythmic risk and sudden cardiac death. However, current evidence suggests that individualized exercise programs, under clinical supervision, can enhance functional capacity, improve quality of life, and sometimes prognosis in selected patients. Contemporary European and North American guidelines suggest that participation in competitive sports may be reasonable for athletes with genetic cardiomyopathies, provided that individual risk is regularly and systematically reassessed. The aim of this review is to synthetize current evidence on exercise training, sports participation and rehabilitation in the three major cardiomyopathies\u2014hypertrophic, dilated, and arrhythmogenic\u2014which have informed the latest international guideline recommendations. Particular attention is given to the essential role of shared decision-making, highlighting the importance of a personalized approach based on the specific type of cardiomyopathy, arrhythmic risk stratification, and individual patient factors. In addition, the review addresses two emerging clinical scenarios: sports participation in patients with implantable cardioverter-defibrillators and current recommendations for genotype-positive\/phenotype-negative individuals at risk of cardiomyopathy.<\/jats:p>","DOI":"10.3390\/jcm14248683","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T16:20:29Z","timestamp":1765210829000},"page":"8683","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exercise Participation and Rehabilitation in Cardiomyopathies: An Updated Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Domitilla","family":"Russo","sequence":"first","affiliation":[{"name":"Department of Cardiology, Santo Spirito Hospital, 00193 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Gambardella","sequence":"additional","affiliation":[{"name":"Unit\u00e0 di Riabilitazione Cardio-Respiratoria, IRCCS San Raffaele Cassino, 03043 Cassino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Volterrani","sequence":"additional","affiliation":[{"name":"IRCSS San Raffaele Roma, Universit\u00e0 San Raffaele-Uniroma 5, 00166 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Lillo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences-Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9642-8380","authenticated-orcid":false,"given":"Massimo","family":"Volpe","sequence":"additional","affiliation":[{"name":"IRCSS San Raffaele Roma, Via di Val Cannuta 250, 00166 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camillo","family":"Autore","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Respiratory Sciences, IRCCS San Raffaele Cassino, Via G. di Biasio, 1, 03043 Cassino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pcad.2023.04.008","article-title":"Exercise and cardiovascular health: A state-of-the-art review","volume":"79","author":"Isath","year":"2023","journal-title":"Prog. Cardiovasc. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1093\/eurheartj\/ehad194","article-title":"ESC Scientific Document Group. 2023 ESC Guidelines for the management of cardiomyopathies","volume":"44","author":"Arbelo","year":"2023","journal-title":"Eur. Heart J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.jacc.2021.01.030","article-title":"Cardiac Rehabilitation for Patients with Heart Failure: JACC Expert Panel","volume":"77","author":"Bozkurt","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"243958","DOI":"10.1155\/2012\/243958","article-title":"Does physical activity increase life expectancy? A review of the literature","volume":"2012","author":"Reimers","year":"2012","journal-title":"J. Aging Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1136\/bjsports-2022-106195","article-title":"Effectiveness of physical activity interventions for improving depression, anxiety and distress: An overview of systematic reviews","volume":"57","author":"Singh","year":"2023","journal-title":"Br. J. Sports Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e000163","DOI":"10.1136\/openhrt-2014-000163","article-title":"Exercise-based rehabilitation for heart failure: Systematic review and meta-analysis","volume":"2","author":"Sagar","year":"2015","journal-title":"Open Heart"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/JSM.0000000000000598","article-title":"Etiology of Sudden Cardiac Arrest and Death in US Competitive Athletes: A 2-Year Prospective Surveillance Study","volume":"30","author":"Peterson","year":"2020","journal-title":"Clin. J. Sport Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1001\/jama.296.13.1593","article-title":"Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program","volume":"296","author":"Corrado","year":"2006","journal-title":"JAMA"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/0735-1097(94)90844-3","article-title":"26th Bethesda conference: Recommendations for determining eligibility for competition in athletes with cardiovascular abnormalities. Task Force 3: Hypertrophic cardiomyopathy, myocarditis and other myopericardial diseases and mitral valve prolapse","volume":"24","author":"Maron","year":"1994","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_10","first-page":"553","article-title":"Exercise and the risk of sudden cardiac death","volume":"31","author":"Corrado","year":"2006","journal-title":"Herz Kardiovaskul\u00e4re Erkrank."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Han, J., Lalario, A., Merro, E., Sinagra, G., Sharma, S., Papadakis, M., and Finocchiaro, G. (2023). Sudden Cardiac Death in Athletes: Facts and Fallacies. J. Cardiovasc. Dev. Dis., 10.","DOI":"10.3390\/jcdd10020068"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.jacc.2005.02.006","article-title":"Introduction: Eligibility recommendations for competitive athletes with cardiovascular abnormalities-general considerations","volume":"45","author":"Maron","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jacc.2021.12.002","article-title":"Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review","volume":"79","author":"Maron","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.amjcard.2012.12.018","article-title":"Physical activity and other health behaviors in adults with hypertrophic cardiomyopathy","volume":"111","author":"Reineck","year":"2013","journal-title":"Am. J. Cardiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.jacc.2013.03.062","article-title":"Obesity and its association to phenotype and clinical course in hypertrophic cardiomyopathy","volume":"62","author":"Olivotto","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jamacardio.2019.4268","article-title":"Association of Obesity with Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy","volume":"5","author":"Fumagalli","year":"2020","journal-title":"JAMA Cardiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e1239","DOI":"10.1161\/CIR.0000000000001250","article-title":"AHA\/ACC\/AMSSM\/HRS\/PACES\/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association\/American College of Cardiology Joint Committee on Clinical Practice Guidelines","volume":"149","author":"Ommen","year":"2024","journal-title":"Circulation"},{"key":"ref_18","first-page":"9","article-title":"Review Article\u2014Exercise and Hypertrophic Cardiomyopathy: Risks, Benefits, and Safety\u2014A Systematic Review and Meta-analysis","volume":"37","author":"Albulushi","year":"2025","journal-title":"J. Saudi Heart Assoc."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1161\/CIRCULATIONAHA.124.070064","article-title":"Exercise Training in Patients with Hypertrophic Cardiomyopathy Without Left Ventricular Outflow Tract Obstruction: A Randomized Clinical Trial","volume":"151","author":"Gudmundsdottir","year":"2025","journal-title":"Circulation"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e000484","DOI":"10.1136\/openhrt-2016-000484","article-title":"Physical activity in hypertrophic cardiomyopathy: Prevalence of inactivity and perceived barriers","volume":"3","author":"Sweeting","year":"2016","journal-title":"Open Heart"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1001\/jama.2017.2503","article-title":"Effect of Moderate-Intensity Exercise Training on Peak Oxygen Consumption in Patients with Hypertrophic Cardiomyopathy: A Randomized Clinical Trial","volume":"317","author":"Saberi","year":"2017","journal-title":"JAMA"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1177\/2047487313501277","article-title":"Efficacy of exercise training in symptomatic patients with hypertrophic cardiomyopathy: Results of a structured exercise training program in a cardiac rehabilitation center","volume":"22","author":"Klempfner","year":"2015","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1001\/jamacardio.2023.1042","article-title":"Vigorous Exercise in Patients with Hypertrophic Cardiomyopathy","volume":"8","author":"Lampert","year":"2023","journal-title":"JAMA Cardiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1093\/eurheartj\/ehae919","article-title":"High intensity exercise programme in patients with hypertrophic cardiomyopathy: A randomized trial","volume":"46","author":"Basu","year":"2025","journal-title":"Eur. Heart J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/j.jacc.2022.08.715","article-title":"Impact of Exercise on Outcomes and Phenotypic Expression in Athletes with Nonobstructive Hypertrophic Cardiomyopathy","volume":"80","author":"Basu","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1136\/bjsports-2019-100890","article-title":"Clinical outcomes in adult athletes with hypertrophic cardiomyopathy: A 7-year follow-up study","volume":"54","author":"Pelliccia","year":"2020","journal-title":"Br. J. Sports Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e031399","DOI":"10.1161\/JAHA.123.031399","article-title":"Randomized Controlled Trial of Moderate- and High-Intensity Exercise Training in Patients with Hypertrophic Cardiomyopathy: Effects on Fitness and Cardiovascular Response to Exercise","volume":"12","author":"MacNamara","year":"2023","journal-title":"J. Am. Heart Assoc."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Zampieri, M., Saberi, S., D\u2019Ascenzi, F., Papadakis, M., Pelliccia, A., and Olivotto, I. (2025). Hypertrophic cardiomyopathy: Changing the paradigm of exercise prescription and competitive sport participation. Eur. Heart J., ehaf770.","DOI":"10.1093\/eurheartj\/ehaf770"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1177\/2047487320928654","article-title":"Prescribing, dosing and titrating exercise in patients with hypertrophic cardiomyopathy for prevention of comorbidities: Ready for prime time","volume":"28","author":"Cavigli","year":"2021","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.jacc.2024.12.025","article-title":"Clinical Considerations for Competitive Sports Participation for Athletes with Cardiovascular Abnormalities: A Scientific Statement from the American Heart Association and American College of Cardiology","volume":"85","author":"Kim","year":"2025","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"e151","DOI":"10.1016\/j.hrthm.2024.05.018","article-title":"2024 HRS expert consensus statement on arrhythmias in the athlete: Evaluation, treatment, and return to play","volume":"21","author":"Lampert","year":"2024","journal-title":"Heart Rhythm"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/eurheartj\/ehaa605","article-title":"ESC Scientific Document Group. 2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease","volume":"42","author":"Pelliccia","year":"2021","journal-title":"Eur Heart J."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1136\/heartjnl-2012-302145","article-title":"Exercise training in dilated cardiomyopathy improves rest and stress cardiac function without changes in cardiac high energy phosphate metabolism","volume":"98","author":"Holloway","year":"2012","journal-title":"Heart"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jare.2012.06.002","article-title":"Correlation between changes in diastolic dysfunction and health-related quality of life after cardiac rehabilitation program in dilated cardiomyopathy","volume":"4","author":"Mehani","year":"2013","journal-title":"J. Adv. Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/HCR.0000000000000382","article-title":"What Is the Optimal Exercise Prescription for Patients With Dilated Cardiomyopathy in Cardiac Rehabilitation? A Systematic Review","volume":"39","author":"Seo","year":"2019","journal-title":"J. Cardiopulm. Rehabil. Prev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1161\/CIRCHEARTFAILURE.111.965186","article-title":"Modest Increase in Peak VO2 Is Related to Better Clinical Outcomes in Chronic Heart Failure Patients","volume":"5","author":"Swank","year":"2012","journal-title":"Circ. Heart Fail."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1016\/j.jacc.2007.09.075","article-title":"Effects of exercise training on myocardial energy metabolism and ventricular function assessed by phosphorus-31 magnetic resonance spectroscopy and MRI in dilated cardiomyopathy","volume":"51","author":"Beer","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0735-1097(02)02772-9","article-title":"Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopathy","volume":"41","author":"Stolen","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/heartjnl-2019-315942","article-title":"Arrhythmic risk stratification in non-ischaemic dilated cardiomyopathy beyond ejection fraction","volume":"106","author":"Boscutti","year":"2020","journal-title":"Heart"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"4400","DOI":"10.1002\/ehf2.14970","article-title":"Personalized care in dilated cardiomyopathy: Rationale and study design of the active DCM trial","volume":"11","author":"Kayvanpour","year":"2024","journal-title":"ESC Heart Fail."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1161\/CIRCRESAHA.117.309345","article-title":"Arrhythmogenic Cardiomyopathy","volume":"121","author":"Corrado","year":"2017","journal-title":"Circ. Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.jacc.2013.06.033","article-title":"Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia\/cardiomyopathy-associated desmosomal mutation carriers","volume":"62","author":"James","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.jacep.2018.01.010","article-title":"Harmful effects of exercise intensity and duration in patients with arrhythmogenic cardiomyopathy","volume":"4","author":"Lie","year":"2018","journal-title":"JACC Clin. Electrophysiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"e010221","DOI":"10.1161\/CIRCEP.121.010221","article-title":"Integrating Exercise into Personalized Ventricular Arrhythmia Risk Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy","volume":"15","author":"Bosman","year":"2022","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1093\/eurheartj\/ehv110","article-title":"Association of competitive and recreational sport participation with cardiac events in patients with arrhythmogenic right ventricular cardiomyopathy: Results from the North American multidisciplinary study","volume":"36","author":"Ruwald","year":"2015","journal-title":"Eur. Heart J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1002\/ejhf.181","article-title":"Vigorous physical activity impairs myocardial function in patients with arrhythmogenic right ventricular cardiomyopathy and in mutation-positive family members","volume":"16","author":"Saberniak","year":"2014","journal-title":"Eur. J. Heart Fail."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"\u00c7imen, T., Wilzeck, V.C., Montrasio, G., Bonetti, N.R., Medeiros-Domingo, A., Grebmer, C., Matter, C.M., Tanner, F.C., Manka, R., and Brunckhorst, C.B. (2022). Biventricular Arrhythmogenic Cardiomyopathy Associated with a Novel Heterozygous Plakophilin-2Early Truncating Variant. J. Clin. Med., 11.","DOI":"10.3390\/jcm11247513"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/europace\/euaa105","article-title":"Exercise restriction is protective for genotype-positive family members of arrhythmogenic right ventricular cardiomyopathy patients","volume":"22","author":"Wang","year":"2020","journal-title":"Europace"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e039125","DOI":"10.1161\/JAHA.124.039125","article-title":"Exercise Prescription in Arrhythmogenic Cardiomyopathy: Finding the Right Balance Between Risks and Benefits","volume":"14","author":"Dei","year":"2025","journal-title":"J. Am. Heart Assoc."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e001471","DOI":"10.1161\/JAHA.114.001471","article-title":"Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia\/cardiomyopathy in patients without desmosomal mutations","volume":"3","author":"Sawant","year":"2014","journal-title":"J. Am. Heart Assoc."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Costa, S., Koch, K., Gasperetti, A., Akdis, D., Brunckhorst, C., Fu, G., Tanner, F.C., Ruschitzka, F., Duru, F., and Saguner, A.M. (2022). Changes in Exercise Capacity and Ventricular Function in Arrhythmogenic Right Ventricular Cardiomyopathy: The Impact of Sports Restriction during Follow-Up. J. Clin. Med., 11.","DOI":"10.3390\/jcm11051150"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.hrthm.2015.08.035","article-title":"Safety of American Heart Association-recommended minimum exercise for desmosomal mutation carriers","volume":"13","author":"Sawant","year":"2016","journal-title":"Heart Rhythm."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1161\/CIRCULATIONAHA.112.000447","article-title":"Safety of sports for athletes with implantable cardioverter-defibrillators: Results of a prospective, multinational registry","volume":"127","author":"Lampert","year":"2013","journal-title":"Circulation"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1161\/CIRCULATIONAHA.117.027828","article-title":"Safety of Sports for Athletes with Implantable Cardioverter-Defibrillators: Long-Term Results of a Prospective Multinational Registry","volume":"135","author":"Lampert","year":"2017","journal-title":"Circulation"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/europace\/euaa106","article-title":"EAPC\/EHRA update of the Recommendations for participation in leisure-time physical activity and competitive sports in patients with arrhythmias and potentially arrhythmogenic conditions. Recommendations for participation in leisure-time physical activity and competitive sports of patients with arrhythmias and potentially arrhythmogenic conditions. Part 2: Ventricular arrhythmias, channelopathies, and implantable defibrillators","volume":"23","author":"Heidbuchel","year":"2021","journal-title":"Europace"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1016\/j.mayocp.2022.03.024","article-title":"Outcomes of Athletes with Genetic Heart Diseases and Implantable Cardioverter-Defibrillators Who Chose to Return to Play","volume":"97","author":"Tobert","year":"2022","journal-title":"Mayo Clin. Proc."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.hrthm.2018.10.032","article-title":"Competitive athletes with implantable cardioverter-defibrillators-How to program? Data from the Implantable Cardioverter- Defibrillator Sports Registry","volume":"16","author":"Olshansky","year":"2019","journal-title":"Heart Rhythm"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0735-1097(20)30932-3","article-title":"Outcomes of sports participation for patients with hypertrophic cardiomyopathy and implantable cardioverter-defibrillators: Data from the ICD Sports Registry","volume":"75","author":"Maron","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.hroo.2024.01.007","article-title":"Safety of Sports for Patients with Subcutaneous Implantable Cardioverter Defibrillator (SPORT S-ICD): Study rationale and protocol","volume":"5","author":"Chorin","year":"2024","journal-title":"Heart Rhythm O2"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.jacc.2023.12.021","article-title":"Sports Participation by Athletes with Cardiovascular Disease","volume":"83","author":"Martinez","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/eurjpc\/zwad079","article-title":"Sport and Exercise in Genotype positive (+) Phenotype negative (\u2212) Individuals: Current Dilemmas and Future Perspectives","volume":"30","author":"Paldino","year":"2023","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.1093\/eurheartj\/ehac262","article-title":"ESC Scientific Document Group 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"43","author":"Zeppenfeld","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Schoonvelde, S.A.C., Alexandridis, G.M., Price, L.B., Schinkel, A.F.L., Hirsch, A., Zwetsloot, P.-P., Kammeraad, J.A.E., van Slegtenhorst, M.A., Verhagen, J.M.A., and de Boer, R.A. (2024). Family screening for hypertrophic cardiomyopathy: Initial cardiologic assessment, and long-term follow-up of genotype-positive phenotype-negative individuals. MedRxiv.","DOI":"10.1101\/2024.11.01.24316619"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"H881","DOI":"10.1152\/ajpheart.00701.2022","article-title":"Beneficial effects of exercise initiated before development of hypertrophic cardiomyopathy in genotype-positive mice","volume":"324","author":"Andreassen","year":"2023","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"zwad125.253","DOI":"10.1093\/eurjpc\/zwad125.253","article-title":"Psychological well-being and illness perception in hypertrophic cardiomy-opathy patients undergoing hybrid cardiac rehabilitation","volume":"30","author":"Mierzynska","year":"2023","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.jjcc.2019.04.013","article-title":"Efficacy and safety of exercise rehabilitation in patients with hypertrophic cardiomyopathy","volume":"74","author":"Wasserstrum","year":"2019","journal-title":"J. Cardiol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"330","DOI":"10.62347\/JOYM3506","article-title":"Physical cardiac rehabilitation effects on cardio-metabolic outcomes in the patients with hypertrophic cardiomyopathy: A systematic review","volume":"14","author":"Chichagi","year":"2024","journal-title":"Am. J. Cardiovasc. Dis."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2459\/JCM.0000000000001388","article-title":"Outcomes of inflammatory cardiomyopathy following cardiac rehabilitation","volume":"24","author":"Peretto","year":"2023","journal-title":"J. Cardiovasc. Med."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"105293","DOI":"10.1016\/j.jaccas.2025.105293","article-title":"Cardiac Rehabilitation in Advanced Dilated Cardiomyopathy Within a Resource-Limited Setting","volume":"30","year":"2025","journal-title":"JACC Case Rep."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/jamacardio.2019.2861","article-title":"Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids)","volume":"4","author":"Norrish","year":"2019","journal-title":"JAMA Cardiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/24\/8683\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T16:52:04Z","timestamp":1765212724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/24\/8683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,8]]},"references-count":71,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["jcm14248683"],"URL":"https:\/\/doi.org\/10.3390\/jcm14248683","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,8]]}}}