{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T10:16:34Z","timestamp":1765880194609,"version":"3.48.0"},"reference-count":21,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Gynecology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Genital discomfort, manifested by vulvar itching and burning, is a frequent complaint among women of all ages and has multifactorial origins\u2014including dermatoses, infections, allergies, and hormonal disorders. The study aimed to determine whether selected medical history factors\u2014age, obstetric history, and body mass index (BMI)\u2014influence the frequency of genital discomfort as a reason for gynecological consultation. Methods: A pilot study included 288 female patients aged 11\u201391 years who presented to outpatient gynecological clinics between September 2018 and February 2025 with symptoms of vulvar itching and genital discomfort. Qualitative data were expressed as numbers and percentages, and age was described using mean, median, quartiles, and range. Associations between categorical variables were assessed using Pearson\u2019s chi-square test, with statistical significance set at p &lt; 0.05. Results: The mean age of patients was 47.4 \u00b1 20.3 years. Most were diagnosed with ICD-10 code N90 (82.6%), while 17.4% had N76. Genital discomfort was most frequently reported by women aged 41\u201350 years (p &lt; 0.0001). Comorbidities (p &lt; 0.0001) and obstetric history (p &lt; 0.0001) significantly influenced the occurrence of genital discomfort, which was more prevalent among women with chronic conditions and those who had been pregnant. No significant associations were found with BMI (p = 0.2353) or menopausal status (p = 0.3458). Conclusions: Genital discomfort is a common and multifactorial condition requiring an interdisciplinary diagnostic and therapeutic approach. Collaboration among gynecologists, dermatologists, endocrinologists, and dietitians is crucial for effective management and prevention.<\/jats:p>","DOI":"10.3390\/jcm14248863","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T09:57:24Z","timestamp":1765879044000},"page":"8863","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of Prophylaxis and Dietotherapy in Gynecology in the Context of the Interdisciplinary Nature of Genital Discomfort\u2014A Pilot Report"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1385-5641","authenticated-orcid":false,"given":"Gra\u017cyna","family":"Jarz\u0105bek-Bielecka","sequence":"first","affiliation":[{"name":"Gynecology Clinic, Poznan University of Medical Sciences, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3695-3245","authenticated-orcid":false,"given":"Agata","family":"Puszcz","sequence":"additional","affiliation":[{"name":"Sexology and Clinical Psychology Student Research Group, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariola","family":"Pawlaczyk","sequence":"additional","affiliation":[{"name":"Katedra i Zak\u0142ad Kosmetologii Praktycznej i Profilaktyki Chor\u00f3b Sk\u00f3ry (KPPS), Poznan University of Medical Sciences, 60-781 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Plagens-Rotman","sequence":"additional","affiliation":[{"name":"Gynecology Clinic, Poznan University of Medical Sciences, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9533-2950","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Mizgier","sequence":"additional","affiliation":[{"name":"Zak\u0142ad Dietetyki Sportowej, Katedra Dietetyki, Wydzia\u0142 Nauk o Zdrowiu, Akademia Wychowania Fizycznego w Poznaniu, 61-871 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Pisarska-Krawczyk","sequence":"additional","affiliation":[{"name":"Nursing Department, Uniwersytet Kaliski, 62-800 Kalisz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8272-7534","authenticated-orcid":false,"given":"Jakub","family":"Mroczyk","sequence":"additional","affiliation":[{"name":"Gynecology Clinic, Poznan University of Medical Sciences, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Witold","family":"K\u0119dzia","sequence":"additional","affiliation":[{"name":"Gynecology Clinic, Poznan University of Medical Sciences, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"ref_1","unstructured":"Engeler, D., Baranowski, A.P., Elneil, S., Hughes, J., Messelink, E.J., van Ophoven, A., and Williams, A.C.d.C. (2024). EAU Guidelines on Chronic Pelvic Pain, European Association of Urology. Chapter 5."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Di Tucci, C., and Muzii, L. (2023). Chronic Pelvic Pain, Vulvar Pain Disorders, and Proteomics Profiles: New Discoveries, New Hopes. Biomedicines, 12.","DOI":"10.3390\/biomedicines12010001"},{"key":"ref_3","unstructured":"World Health Organization (2004). International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10), World Health Organization. [2nd ed.]."},{"key":"ref_4","first-page":"100836","article-title":"Evaluation of Vulvovaginitis in the Adolescent Patient","volume":"50","author":"Itriyeva","year":"2020","journal-title":"Curr. Probl. Pediatr. Adolesc. Health Care"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/1471-0528.13263","article-title":"Dyspareunia and childbirth: A prospective cohort study","volume":"122","author":"McDonald","year":"2015","journal-title":"Int. J. Obstet. Gynaecol."},{"key":"ref_6","first-page":"S54","article-title":"Vulvar Diseases in Postmenopausal Women","volume":"103","author":"Pawlaczyk","year":"2016","journal-title":"Prz. Derm."},{"key":"ref_7","first-page":"153","article-title":"Childhood Vulvar Dermatoses","volume":"18","author":"Pawlaczyk","year":"2004","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1515\/sjpain-2021-0223","article-title":"Chronic vulvar pain in gynecological outpatients","volume":"23","author":"Teigen","year":"2022","journal-title":"Scand. J. Pain"},{"key":"ref_9","first-page":"59","article-title":"Fibromialgia w praktyce lekarza rodzinnego","volume":"10","author":"Kanecki","year":"2016","journal-title":"Forum Med. Rodz."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jogc.2019.02.013","article-title":"Prevalence of Pelvic Floor Disorders in the Fibromyalgia Population: A Systematic Review","volume":"42","author":"Thornton","year":"2020","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.11648\/j.jgo.20241202.14","article-title":"Basic Characteristics and Demographic Data in Patients with Chronic Vulvar Discomfort: A Detailed Analysis of DATRIV Study","volume":"12","author":"Harni","year":"2024","journal-title":"J. Gynecol. Obstet."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Woodd, S.L., Montoya, A., Barreix, M., Pi, L., Calvert, C., Rehman, A.M., Chou, D., and Campbell, O.M.R. (2019). Incidence of maternal peripartum infection: A systematic review and meta-analysis. PLoS Med., 16.","DOI":"10.1371\/journal.pmed.1002984"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Govender, V., Naidoo, M., and Moodley, D. (2024). Sexually transmitted infections and bacterial vaginosis among adolescent girls and young women in the early postpartum period: A cross-sectional study. BMC Infect. Dis., 24.","DOI":"10.1186\/s12879-024-09781-4"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Condrat, C.E., Filip, L., Gherghe, M., Cretoiu, D., and Suciu, N. (2021). Maternal HPV Infection: Effects on Pregnancy Outcome. Viruses, 13.","DOI":"10.3390\/v13122455"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5070\/D35HS3F52V","article-title":"Pattern of non-venereal dermatoses of female external genitalia in South India","volume":"14","author":"Singh","year":"2008","journal-title":"Dermatol. Online J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"305","DOI":"10.18231\/j.ijced.2024.054","article-title":"A cross-sectional study on female genital dermatoses of non-venereal and non-infectious etiology","volume":"10","author":"Parmar","year":"2024","journal-title":"IP Indian J. Clin. Exp. Dermatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.abd.2021.11.006","article-title":"Vulvar dermatoses: A cross-sectional 5-year study. Experience in a specialized vulvar unit","volume":"97","author":"Pozo","year":"2022","journal-title":"Bras. Dermatol."},{"key":"ref_18","first-page":"WC01","article-title":"Non-venereal female genital dermatoses: Beyond sexually transmitted infections: A cross-sectional study","volume":"17","author":"Danny","year":"2023","journal-title":"J. Clin. Diagn. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1080\/13697137.2018.1446930","article-title":"The European Vulvovaginal Epidemiological Survey (EVES): Prevalence, symptoms and impact of vulvovaginal atrophy of menopause","volume":"21","author":"Palacios","year":"2018","journal-title":"Climacteric"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"159.e1","DOI":"10.1016\/j.ajog.2021.02.034","article-title":"Association between postmenopausal vulvovaginal discomfort, vaginal microbiota, and mucosal inflammation","volume":"225","author":"Mitchell","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_21","first-page":"77","article-title":"Estimation of the age at natural menopause in a population-based study of Polish women","volume":"6","author":"Kaczmarek","year":"2007","journal-title":"Przegl\u0105d Menopauzalny"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/24\/8863\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T10:14:34Z","timestamp":1765880074000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/24\/8863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,15]]},"references-count":21,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["jcm14248863"],"URL":"https:\/\/doi.org\/10.3390\/jcm14248863","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,15]]}}}