{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:47:47Z","timestamp":1792118867560,"version":"4.4.0"},"reference-count":27,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: The aim of this study was to evaluate changes in corneal topography, wavefront aberrations, and densitometry after superficial keratectomy (SK) for Salzmann nodular degeneration (SND). Methods: This was an observational retrospective study. Pre- and post-operative data, including best spectacle-corrected visual acuity (BCVA), refraction, and Pentacam\u00ae topography scans, were analysed. Changes in keratometry (K), wavefront aberrations, and corneal optical densitometry (COD) were evaluated. Results: A total of 21 eyes of 17 patients who underwent SK for SND were included. At an average follow-up of 6.3 \u00b1 4.4 months, there was a significant reduction in RMS (root mean square) values for total wavefront aberrations after surgery (mean reduction: \u22123.89 \u00b1 4.08 \u03bcm, p = 0.001), lower-order aberrations (mean reduction: \u22123.47 \u00b1 3.52 \u03bcm, p = 0.001), and higher-order aberrations (mean: \u22120.42 \u00b1 0.58 \u03bcm, p &lt; 0.001). There was a significant improvement in BCVA (mean change: 0.27 \u00b1 0.31 logMAR, p &lt; 0.001) and spherical equivalent (mean change: \u22122.09 \u00b1 2.73 D, p = 0.002), and a reduction in refractive cylinder (mean reduction: \u22120.85 \u00b1 1.14 D, p = 0.008). There was a significant reduction in corneal astigmatism (mean reduction 1.04 \u00b1 2.88 D; p = 0.041), and an increase in flat keratometry (mean change 1.46 \u00b1 3.10 D; p = 0.029). Lastly, there was a significant decrease in total COD values in all zones except for the central 2 mm (p &lt; 0.05) and in the overall total 12 mm cornea (p = 0.035). Conclusions: SK for SND resulted in better visual acuity and potentially improved quality as suggested by the reduction in corneal aberrations and improvement in corneal regularity and transparency.<\/jats:p>","DOI":"10.3390\/jcm15010178","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T08:38:14Z","timestamp":1766738294000},"page":"178","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Superficial Keratectomy on Corneal Topography, Aberration, and Densitometry in Salzmann Nodular Degeneration"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4749-4143","authenticated-orcid":false,"given":"Ziqiao","family":"Qi","sequence":"first","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0325-6461","authenticated-orcid":false,"given":"Ritika","family":"Mukhija","sequence":"additional","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9815-1701","authenticated-orcid":false,"given":"Gabriella","family":"Quiney","sequence":"additional","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0667-3700","authenticated-orcid":false,"given":"Mayank A.","family":"Nanavaty","sequence":"additional","affiliation":[{"name":"Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BF, UK"},{"name":"Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jtos.2015.08.006","article-title":"Salzmann\u2019s nodular degeneration","volume":"14","author":"Maharana","year":"2016","journal-title":"Ocul. 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