{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T16:10:03Z","timestamp":1768234203542,"version":"3.49.0"},"reference-count":27,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder, with a prevalence of approximately 16% in Saudi Arabia. PCOS is associated with various health complications. Assessing the quality of life (QoL) of women with PCOS is crucial for effective management. Objectives: This study aims to translate and validate the Polycystic Ovary Syndrome Quality of Life scale (PCOSQOL) into Arabic for use among Arabic-speaking women. The study was designed to evaluate the psychometric properties of the Arabic PCOSQOL, including its reliability, validity, and responsiveness. Methods: A cross-sectional study was conducted among 207 Saudi women diagnosed with PCOS. Participants were recruited from family medicine and obstetrics and gynecology clinics at King Saud University Medical City, Riyadh, through an online survey. The PCOSQOL was translated into Arabic following the World Health Organization\u2019s (WHO) forward\u2013backward translation protocol. Psychometric evaluation included internal consistency, test\u2013retest reliability (ICC), and construct validity. Results: The Arabic PCOSQOL demonstrated excellent psychometric performance, with high internal consistency (Cronbach\u2019s \u03b1 = 0.951) and good-to-excellent test\u2013retest reliability (ICC = 0.760\u20130.885). Construct validity was supported by a four-factor structure explaining 62.5% of the total variance (KMO = 0.92; Bartlett\u2019s p &lt; 0.001). The subscales showed strong factor loadings (0.49\u20130.97). Older women (&gt;25 years), married participants, and residents of the western and central regions reported significantly better quality of life (p &lt; 0.05). Conclusions: The Arabic version of the PCOSQOL demonstrated excellent reliability, validity, and stability, confirming its suitability for assessing quality of life among Arabic-speaking women with PCOS. This validated tool can support both clinical practice and future research across Arabic populations.<\/jats:p>","DOI":"10.3390\/jcm15020607","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T12:44:44Z","timestamp":1768221884000},"page":"607","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Validation and Cross-Cultural Adaptation of the Arabic Version of the Polycystic Ovary Syndrome Quality of Life Scale (PCOSQOL)"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3434-5095","authenticated-orcid":false,"given":"Layan","family":"Alwatban","sequence":"first","affiliation":[{"name":"University Family Medicine Center, King Saud University Medical City (KSUMC), King Saud University (KSU), P.O. Box 7805, Riyadh 11472, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2245-3054","authenticated-orcid":false,"given":"Ayah","family":"Sayed","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raneem","family":"Alwatban","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mais","family":"Alwatban","sequence":"additional","affiliation":[{"name":"College of Medicine, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9142-425X","authenticated-orcid":false,"given":"Nada","family":"Alyousefi","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, College of Medicine, King Saud University (KSU), P.O. Box 2925, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"ref_1","unstructured":"Rotterdam ESHRE\/ASRM-Sponsored PCOS Consensus Workshop Group (2003, January 1\u20133). Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). 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