{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:17:09Z","timestamp":1792804629925,"version":"4.5.0"},"reference-count":20,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: Robotic-Assisted Thoracic Surgery (RATS) has emerged as a viable alternative to traditional median sternotomy for patients with anterior mediastinal tumors suspected of having thymoma or those with Myasthenia Gravis (MG). While median sternotomy remains a widely accepted standard approach, RATS has gained popularity due to its potential benefits. Methods: We retrospectively reviewed our 5 years\u2019 experience of performing 111 surgeries for patients with anterior mediastinal tumors and patients with MG suspected of having thymoma. We performed multivariate regression models to assess the association between main demographic and clinical variables and two primary outcomes: overall complications and hospital stay. Results: Out of 111 patients, 54 were men (48.6%) and 57 were women (51.4%). The majority of surgeries (n = 93) were performed by RATS (83.8%), while the remainder were performed by either median sternotomy (n = 15, 13.5%) or by other approaches (n = 3, 2.7%). Sixty-five patients were diagnosed with thymoma (58.6%), with 96.9% R0 resection. Sixty-five patients underwent left-sided surgery (58.6%), and thirty-one underwent right-sided surgery (27.9%). The conversion rate was 2.5%. The rate of postoperative complications was 8.1 without perioperative mortality. The median hospital stay was 4.62 days, but it was significantly shorter in the RATS compared to the median sternotomy group (mean 3.64 vs. 10.67 days, p = 0.040). Conclusions: Our results suggest that RATS for patients with anterior mediastinal tumors suspected of having thymoma or for those with MG is safe and technically feasible and may be the preferred surgical approach for selected patients, whereas traditional median sternotomy remains the preferred choice for more locally advanced tumors.<\/jats:p>","DOI":"10.3390\/jcm15020638","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T15:52:57Z","timestamp":1768319577000},"page":"638","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Shift from Standard Median Sternotomy to Robotic-Assisted Thoracic Surgery for Resection of Anterior Mediastinal Tumors"],"prefix":"10.3390","volume":"15","author":[{"given":"Michael","family":"Peer","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharbel","family":"Azzam","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nachum","family":"Nesher","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Kolodii","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1040-9312","authenticated-orcid":false,"given":"Yaacov","family":"Abramov","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9219-365X","authenticated-orcid":false,"given":"Vladimir","family":"Verenkin","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Pain, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6082-6862","authenticated-orcid":false,"given":"Ruth","family":"Shaylor","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Pain, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-7900","authenticated-orcid":false,"given":"Arnon","family":"Karni","sequence":"additional","affiliation":[{"name":"Neurology Institute, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1917-9349","authenticated-orcid":false,"given":"Avi","family":"Gadoth","sequence":"additional","affiliation":[{"name":"Neurology Institute, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5958-1423","authenticated-orcid":false,"given":"Eugenio","family":"Pompeo","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tor Vergata University of Rome, 00133 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idit","family":"Matot","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology, Intensive Care and Pain, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer","family":"Merimsky","sequence":"additional","affiliation":[{"name":"Division of Oncology, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Weitzman Street 6, Tel Aviv 6423906, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/1759-7714.14234","article-title":"Robot-assisted thoracic surgery versus video-assisted thoracic surgery for treatment of patients with thymoma: A systematic review and meta-analysis","volume":"13","author":"Shen","year":"2022","journal-title":"Thorac. 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Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/2\/638\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T16:07:13Z","timestamp":1768320433000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/2\/638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,13]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["jcm15020638"],"URL":"https:\/\/doi.org\/10.3390\/jcm15020638","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,13]]}}}