{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T01:05:35Z","timestamp":1770685535808,"version":"3.49.0"},"reference-count":19,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: Nasal obstruction is a common presenting symptom in otolaryngology practice. Frequent etiologies include allergic and non-allergic rhinitis, inferior turbinate hypertrophy (HIT), and nasal septal deviation (DNS). This study aimed to evaluate the relationship between major causes of nasal obstruction and their effect on patient-reported quality of life (QoL). Methods: We conducted a retrospective analysis of patients presenting with nasal obstruction who completed the 22-item Sino-Nasal Outcome Test (SNOT-22), the Nasal Obstruction Symptom Evaluation (NOSE) scale, and a visual analog scale (VAS). Patients were categorized into three groups based on etiology: rhinitis, anatomical obstruction, or combined pathology. Results: The study included 170 patients (62% male), with a mean age of 38.4 years. Mean SNOT-22, NOSE, and VAS scores were 38, 61, and 6.5, respectively, with no statistically significant differences observed among the three etiologic groups. QoL outcomes were also comparable across anatomical subgroups, including isolated DNS, HIT, or combined findings. Among SNOT-22 domains, rhinologic symptoms demonstrated the highest burden. Patients with rhinitis exhibited significantly higher rhinologic and ear\/facial symptom scores compared with patients with isolated anatomical obstruction (p = 0.04 and p = 0.005, respectively). Strong correlations were observed between SNOT-22, NOSE, and VAS scores across the entire cohort. Conclusions: Nasal obstruction is associated with substantial impairment in multiple domains of quality of life, independent of the underlying etiology. These findings highlight the broad impact of nasal obstruction on patient well-being. Larger prospective studies are warranted to further assess changes in quality of life following medical and surgical interventions.<\/jats:p>","DOI":"10.3390\/jcm15041320","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T08:15:54Z","timestamp":1770624954000},"page":"1320","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality of Life Among Patients with Nasal Obstruction\u2014Does Etiology Matter?"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5558-6000","authenticated-orcid":false,"given":"Lev","family":"Chvatinski","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Hillel Yaffe Medical Center, Ha-Shalom St, Hadera 3820302, Israel"},{"name":"Rappaport Faculty of Medicine, Technion\u2013Israel Institute of Technology, Efron Street 1, Bat Galim, Haifa 3109601, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7075-8752","authenticated-orcid":false,"given":"Lirit","family":"Levi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center-Beilinson Campus, 39 Jabotinsky St., Petah Tikva 4941492, Israel"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6669-4373","authenticated-orcid":false,"given":"Amir","family":"Levi","sequence":"additional","affiliation":[{"name":"Sagol School of Neuroscience, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Oved","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba 4428164, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center-Beilinson Campus, 39 Jabotinsky St., Petah Tikva 4941492, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9200-5682","authenticated-orcid":false,"given":"Aiman El","family":"Mograbi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center-Beilinson Campus, 39 Jabotinsky St., Petah Tikva 4941492, Israel"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimrod","family":"Amitai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center-Beilinson Campus, 39 Jabotinsky St., Petah Tikva 4941492, Israel"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3300-5698","authenticated-orcid":false,"given":"Itzhak","family":"Braverman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Hillel Yaffe Medical Center, Ha-Shalom St, Hadera 3820302, Israel"},{"name":"Rappaport Faculty of Medicine, Technion\u2013Israel Institute of Technology, Efron Street 1, Bat Galim, Haifa 3109601, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethan","family":"Soudry","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center-Beilinson Campus, 39 Jabotinsky St., Petah Tikva 4941492, Israel"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.4193\/Rhin16.210","article-title":"Airflow and symptom outcomes between allergic and non-allergic rhinitis patients from turbinoplasty","volume":"55","author":"Parthasarathi","year":"2017","journal-title":"Rhinology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000077531","article-title":"Nasal obstruction in patients with seasonal allergic rhinitis: Relationships between allergic inflammation and nasal airflow","volume":"134","author":"Ciprandi","year":"2004","journal-title":"Int. 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Sci."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/4\/1320\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T08:41:25Z","timestamp":1770626485000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/4\/1320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,7]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,2]]}},"alternative-id":["jcm15041320"],"URL":"https:\/\/doi.org\/10.3390\/jcm15041320","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,7]]}}}