{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:00:04Z","timestamp":1771920004537,"version":"3.50.1"},"reference-count":25,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T00:00:00Z","timestamp":1771718400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institutes of Health, Bethesda, MD","award":["R01EY030501"],"award-info":[{"award-number":["R01EY030501"]}]},{"name":"National Institutes of Health, Bethesda, MD","award":["R01EY038008"],"award-info":[{"award-number":["R01EY038008"]}]},{"name":"Research to Prevent Blindness\/David L. Epstein Career Advancement Award in Glaucoma Research sponsored by Alcon"},{"name":"American Glaucoma Society Mid-Career Physician Research Grant"},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Steroid-induced glaucoma (SIG) or ocular hypertension is a well-known complication after corticosteroid exposure to the eye, particularly intravitreal dexamethasone implantation. The main mechanism of elevated intraocular pressure (IOP) is trabecular meshwork dysfunction, leading to increased aqueous outflow resistance. Although most SIG cases respond to medical treatment, some patients develop persistent IOP elevation, requiring surgical intervention. Minimally invasive glaucoma surgery (MIGS) has recently emerged as a safer surgical option, but there are a limited number of reports using MIGS for SIG. Methods: A 73-year-old man, who had branch retinal vein occlusion with refractory macular edema despite multiple anti-VEGF injections, received an intravitreal Ozurdex\u00ae (Allergan, Irvine, CA, USA) implant. He developed marked IOP elevation from 17 to 34 mmHg despite maximal topical therapy. Visual field progression and progressive retinal nerve fiber layer thinning were also observed. Given the need for continued ocular steroid use and only having one arm due to trauma making drops difficult, three trabecular micro-bypass stent devices (iStent infinite\u00ae, Glaukos Corp., Aliso Viejo, CA, USA) were implanted for IOP control. Postoperatively, IOP decreased to 13 mmHg and remained stable at 15 mmHg for 12 months. Additionally, macular edema was well-controlled with ongoing Ozurdex treatment and no observed IOP spikes. Conclusions: This is the first reported case of SIG-associated Ozurdex successfully managed with triple trabecular micro-bypass stents. The iStent infinite implantation provided safe and sustained IOP control for SIG, highlighting its potential role in patients requiring continuous intravitreal steroids.<\/jats:p>","DOI":"10.3390\/jcm15041658","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T08:58:21Z","timestamp":1771837101000},"page":"1658","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sustained Intraocular Pressure Control After iStent Infinite\u00ae Implantation for Steroid-Induced Glaucoma: A Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"Kyunghee","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Nephrology, Hypertension and Kidney Transplantation, University of California, Irvine, CA 92868, USA"},{"name":"Division of Nephrology, Internal Medicine, Daegu Veterans Health Service Medical Center, Daegu 42835, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3127-7160","authenticated-orcid":false,"given":"Je Hyun","family":"Seo","sequence":"additional","affiliation":[{"name":"Veterans Medical Research Institute, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie Jay","family":"Katz","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital, Philadelphia, PA 19107, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex S.","family":"Huang","sequence":"additional","affiliation":[{"name":"Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, San Diego, CA 92037, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3807-4163","authenticated-orcid":false,"given":"Su-Ho","family":"Lim","sequence":"additional","affiliation":[{"name":"Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, San Diego, CA 92037, USA"},{"name":"Department of Ophthalmology, Daegu Veterans Health Service Medical Center, Daegu 42835, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000328630","article-title":"Steroid-induced iatrogenic glaucoma","volume":"47","author":"Razeghinejad","year":"2012","journal-title":"Ophthalmic Res."},{"key":"ref_2","first-page":"170","article-title":"Acute effects of dexamethasone on intraocular pressure in glaucoma","volume":"26","author":"Weinreb","year":"1985","journal-title":"Invest. 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