{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T15:45:40Z","timestamp":1772725540683,"version":"3.50.1"},"reference-count":16,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of Health with Ricerca Corrente and 5 \u00d7 1000 funds"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background. Chondrosarcomas of the manubrium are exceedingly rare, accounting for approximately 20% of all primary bone malignancies, and present unique challenges in surgical management and reconstruction. Reliable reconstructive strategies for medial clavicular stabilization remain limited. Case Presentation. We report the first documented use of STRATOS bars for unilateral clavicular stabilization following manubrial chondrosarcoma resection. A 19-year-old woman with a poorly differentiated (G3) chondrosarcoma of the manubrium underwent neoadjuvant chemotherapy followed by en bloc resection of the manubrium, medial clavicle, and first rib. Reconstruction and clavicular stabilization were achieved using STRATOS, which is traditionally employed for chest-wall reconstruction. This represents a novel use of the device for medial clavicular stabilization after SCJ resection. At the 6-month follow-up, the patient remained disease-free, with preserved shoulder function and stable reconstruction. STRATOS provided stable fixation, preserved shoulder function, and an excellent cosmetic outcome. A brief review of the literature on sternal chondrosarcoma and reconstruction techniques is also presented. Conclusion. This unique application expands the reconstructive possibilities of modular titanium systems. It may offer a more reliable biomechanical alternative to traditional fixation methods in cases requiring stability of the shoulder girdle after SCJ resection. Further validation through biomechanical studies and larger case series is warranted.<\/jats:p>","DOI":"10.3390\/jcm15052002","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T14:19:21Z","timestamp":1772720361000},"page":"2002","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Novel Application of STRATOS for Restoration of Clavicular Stability After Oncologic Sternoclavicular Joint Resection: A Case Report and Review of the Literature"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3157-3720","authenticated-orcid":false,"given":"Shehab","family":"Mohamed","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1153-3334","authenticated-orcid":false,"given":"Luca","family":"Bertolaccini","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7922-7061","authenticated-orcid":false,"given":"Roberto","family":"Gasparri","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2629-7781","authenticated-orcid":false,"given":"Giorgio","family":"Lo Iacono","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5330-5495","authenticated-orcid":false,"given":"Antonio","family":"Mazzella","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5986-7811","authenticated-orcid":false,"given":"Monica","family":"Casiraghi","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Bardoni","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8619-961X","authenticated-orcid":false,"given":"Cristina","family":"Diotti","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Spaggiari","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, IEO\u2014Istituto Europeo di Oncologia, European Institute of Oncology IRCCS, 20141 Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1634\/theoncologist.2007-0237","article-title":"The clinical approach towards chondrosarcoma","volume":"13","author":"Gelderblom","year":"2008","journal-title":"Oncologist"},{"key":"ref_2","first-page":"283","article-title":"Sternal chondrosarcoma: Review of the literature and report of two cases","volume":"72","author":"Widhe","year":"2001","journal-title":"Acta Orthop. Scand."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.21873\/anticanres.14097","article-title":"Chondrosarcoma of the Chest Wall: A Review of 53 Cases from Two Institutions","volume":"40","author":"Lenze","year":"2020","journal-title":"Anticancer Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1093\/annonc\/mdt374","article-title":"Advanced chondrosarcomas: Role of chemotherapy and survival","volume":"24","author":"Italiano","year":"2013","journal-title":"Ann. Oncol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"10136","DOI":"10.12659\/MSM.919184","article-title":"Risk Factors for Incidence and Prognosis in Chondrosarcoma Patients with Pulmonary Metastasis at Initial Diagnosis","volume":"25","author":"Nguyen","year":"2019","journal-title":"Med. Sci. Monit."},{"key":"ref_6","first-page":"123","article-title":"Surgical treatment and outcome of sternal chondrosarcoma","volume":"4","author":"Widhe","year":"2000","journal-title":"Sarcoma"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"737","DOI":"10.21037\/jtd-23-621","article-title":"Management of complications after chest wall resection and reconstruction: A narrative review","volume":"16","author":"Lampridis","year":"2024","journal-title":"J. Thorac. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/SAP.0000000000003334","article-title":"Chondrosarcoma of the Chest Wall: A Single Institution Review of 50 Cases","volume":"90","author":"Laitinen","year":"2023","journal-title":"Ann. Plast. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ejcts.2009.12.046","article-title":"Malignant primary chest-wall tumours: Techniques of reconstruction and survival","volume":"38","author":"Gonfiotti","year":"2010","journal-title":"Eur. J. Cardio-Thorac. Surg."},{"key":"ref_10","first-page":"129","article-title":"Sternal pseudoarthrosis after resternotomy treated with the Strasbourg Thoracic Osteosyntheses System: A case report","volume":"20","author":"Janilionis","year":"2013","journal-title":"Acta Med. Litu."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1016\/j.athoracsur.2013.10.111","article-title":"Sternal dehiscence after clamshell incision in lung transplantation treated with the STRAsbourg Thoracic Osteosyntheses System (STRATOS)","volume":"97","author":"Orsini","year":"2014","journal-title":"Ann. Thorac. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"539","DOI":"10.5090\/jcs.21.055","article-title":"STRATOS titanium rib bridge for chest-wall reconstruction after infantile fibrosarcoma resection: A case report","volume":"54","author":"Llalle","year":"2021","journal-title":"J. Chest Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1055\/s-0031-1285873","article-title":"Thoracic wall reconstruction for primary malignancies in children: Short- and long-term results","volume":"22","author":"Dingemann","year":"2012","journal-title":"Eur. J. Pediatr. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1093\/icvts\/ivt394","article-title":"STRATOS system for the repair of pectus excavatum","volume":"17","author":"Stefani","year":"2013","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.21037\/asj-23-36","article-title":"Titanium devices for chest-wall surgery: A systematic review","volume":"4","author":"Farronato","year":"2024","journal-title":"AME Surg. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/1817-1737.105722","article-title":"A novel technique for the reconstruction of resected sternoclavicular joints: A case report with review of the literature","volume":"8","author":"Hajjar","year":"2013","journal-title":"Ann. Thorac. Med."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/5\/2002\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T14:48:23Z","timestamp":1772722103000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/5\/2002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,5]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["jcm15052002"],"URL":"https:\/\/doi.org\/10.3390\/jcm15052002","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,5]]}}}