{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:23:02Z","timestamp":1777414982594,"version":"3.51.4"},"reference-count":26,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Standardized reporting of astigmatism outcomes is essential for comparability, reproducibility, and interpretation of refractive surgery studies. Vectorial analyses based on established metrics are increasingly required by major journals, yet no freely available tool exists for generating publication-ready vector analysis tables with statistical comparisons. This study presents AstigMETRICS, a standalone application for automated calculation, formatting, and statistical comparison of standard vector metrics in refractive surgery. Methods: AstigMETRICS was developed in MATLAB and compiled as a standalone executable requiring no programming knowledge. The software accepts preoperative, intended, and postoperative astigmatism data in spreadsheet format for both refractive and corneal measurements. It calculates seven standard vector metrics following the Alpins method: the target-induced astigmatism (TIA), surgically induced astigmatism (SIA), difference vector (DV), correction index (CI), magnitude of error (ME), angle of error (AE), and index of success (IOS). Statistical comparisons are performed automatically using appropriate parametric or nonparametric tests for paired and unpaired study designs, with p-values and Cohen\u2019s d effect sizes reported. Results: AstigMETRICS generates standardized tables reporting the means, standard deviations, and clinically relevant proportions (percentage of eyes with an ME within \u00b10.50 D or \u00b11.00 D, and an AE within \u00b115\u00b0). Three simulated datasets were created to validate the software functionality across common surgical scenarios: a contralateral eye laser vision correction, toric phakic IOL implantation, and cataract surgery with toric IOLs. The output tables are displayed in standardized format and saved as high-resolution TIFF images suitable for publication. The software is freely available and a download link is provided in this article. Conclusions: AstigMETRICS enables clinicians and researchers to perform standardized, reproducible astigmatism vector analyses with built-in statistical comparisons. This freely available tool simplifies outcome reporting and improves methodological consistency in refractive surgery research.<\/jats:p>","DOI":"10.3390\/jcm15052018","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T09:22:14Z","timestamp":1772788934000},"page":"2018","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["AstigMETRICS: An Automated Tool for Standardized Vector Metrics Tables and Group Comparisons in Refractive Surgery"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8600-5982","authenticated-orcid":false,"given":"Mathieu","family":"Gauvin","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, McGill University, Montreal, QC H4A 3S5, Canada"},{"name":"LASIK MD, Montreal, QC H4A 3S5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3081-1763","authenticated-orcid":false,"given":"Avi","family":"Wallerstein","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, McGill University, Montreal, QC H4A 3S5, Canada"},{"name":"LASIK MD, Montreal, QC H4A 3S5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3928\/1081597X-20140903-01","article-title":"JRS standard for reporting astigmatism outcomes of refractive surgery","volume":"30","author":"Reinstein","year":"2014","journal-title":"J. Refract. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3928\/1081597X-20170302-01","article-title":"Standard for Reporting Refractive Outcomes of Intraocular Lens-Based Refractive Surgery","volume":"33","author":"Reinstein","year":"2017","journal-title":"J. Refract. Surg."},{"key":"ref_3","first-page":"45","article-title":"Standardized data collection & reporting for refractive surgery","volume":"8","author":"Waring","year":"1992","journal-title":"Refrative Corneal Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0886-3350(98)80305-2","article-title":"Format for reporting refractive surgical data","volume":"24","author":"Koch","year":"1998","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_5","first-page":"459","article-title":"Standard graphs for reporting refractive surgery","volume":"16","author":"Waring","year":"2000","journal-title":"J. Refract. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3928\/1081597X-20101116-01","article-title":"Standardized Graphs and Terms for Refractive Surgery Results","volume":"27","author":"Waring","year":"2011","journal-title":"J. Refract. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcrs.2010.11.010","article-title":"Standardized graphs and terms for refractive surgery results","volume":"37","author":"Dupps","year":"2011","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1097\/ICO.0b013e31820a0e53","article-title":"Standardized Graphs and Terms for Refractive Surgery Results","volume":"30","author":"Stulting","year":"2011","journal-title":"Cornea"},{"key":"ref_9","unstructured":"Surgery, T.J.o.C.a.R. (2025, December 07). Guide for Authors. Available online: https:\/\/www.elsevier.com\/journals\/journal-of-cataract-and-refractive-surgery\/0886-3350\/guide-for-authors."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0886-3350(00)00798-7","article-title":"Astigmatism analysis by the Alpins method","volume":"27","author":"Alpins","year":"2001","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"528","DOI":"10.3928\/1081-597X-20060601-01","article-title":"Terms used for the analysis of astigmatism","volume":"22","author":"Alpins","year":"2006","journal-title":"J. Refract. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0886-3350(13)80617-7","article-title":"A New Method of Analyzing Vectors for Changes in Astigmatism","volume":"19","author":"Alpins","year":"1993","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/S0886-3350(97)80021-1","article-title":"Vector analysis of astigmatism changes by flattening, steepening, and torque","volume":"23","author":"Alpins","year":"1997","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1177\/112067211002000102","article-title":"Corneal higher-order aberrations in amblyopia","volume":"20","author":"Plech","year":"2010","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jcrs.2009.07.043","article-title":"Microincision cataract surgery with toric intraocular lens implantation for correcting moderate and high astigmatism: Pilot study","volume":"36","author":"Alio","year":"2010","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"505","DOI":"10.3928\/1081597X-20090814-01","article-title":"Corneal limbal marking in the treatment of myopic astigmatism with the excimer laser","volume":"26","author":"Bucher","year":"2010","journal-title":"J. Refract. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.jcrs.2010.04.029","article-title":"Modification and refinement of astigmatism in keratoconic eyes with intrastromal corneal ring segments","volume":"36","author":"Pinero","year":"2010","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jcrs.2014.07.038","article-title":"Vector analysis of astigmatism correction after toric intraocular lens implantation","volume":"41","author":"Krall","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.5301\/ejo.5000063","article-title":"Vectorial astigmatic changes after corneal collagen crosslinking in keratoconic corneas previously treated with intracorneal ring segments: A preliminary study","volume":"22","author":"Pinero","year":"2012","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jcrs.2012.10.043","article-title":"Femtosecond laser-assisted intrastromal arcuate keratotomy to reduce corneal astigmatism","volume":"39","author":"Ruckl","year":"2013","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.jcrs.2014.09.036","article-title":"Influence of intraocular astigmatism on the correction of myopic astigmatism by femtosecond laser small-incision lenticule extraction","volume":"41","author":"Qian","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.jcrs.2017.09.023","article-title":"Clinically significant laser in situ keratomileusis flap striae","volume":"43","author":"Wallerstein","year":"2017","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/OPTH.S118831","article-title":"Under-flap stromal bed CXL for early post-LASIK ectasia: A novel treatment technique","volume":"11","author":"Wallerstein","year":"2016","journal-title":"Clin. Ophthalmol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3928\/1081-597X-20060101-16","article-title":"Standardized analyses of correction of astigmatism by laser systems that reshape the cornea","volume":"22","author":"Eydelman","year":"2006","journal-title":"J. Refract. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Gauvin, M., and Wallerstein, A. (2018). AstigMATIC: An automatic tool for standard astigmatism vector analysis. BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0920-1"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Gauvin, M., and Wallerstein, A. (2023). mEYEstro software: An automatic tool for standardized refractive surgery outcomes reporting. 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