{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:41:55Z","timestamp":1773056515171,"version":"3.50.1"},"reference-count":39,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Instituto de Salud Carlos III (ISCIII), Spanish Ministry of Science and Innovation, and co-funded by the European Union","award":["PI22\/00601"],"award-info":[{"award-number":["PI22\/00601"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Frontal sinus fractures are uncommon injuries that may cause persistent aesthetic deformity when the anterior wall is comminuted, as small irregular fragments are difficult to stabilize with conventional osteosynthesis alone. Methods: We describe a point-of-care digital workflow combining 3D planning\/printing and cyanoacrylate-assisted fixation for an isolated comminuted anterior frontal sinus wall fracture. A young adult presented with a depressed forehead contour after assault; computed tomography confirmed at least four displaced fragments. Results: A two-part 3D-printed biomodel was manufactured in-house to visualize the defect and guide extracorporeal reconstruction. Through a coronal approach, fragments were mobilized and anatomically reassembled using the biomodel as a reference; sinonasal drainage was preserved and sinus obliteration was not required. Because fragment size and geometry limited screw purchase, a modified N-butyl-2-cyanoacrylate adhesive (Glubran 2) was applied as an adjunct to maintain reduction, followed by reinforcement with titanium microplates. Postoperative recovery was uneventful, with immediate restoration of forehead contour and no early complications; postoperative imaging confirmed satisfactory alignment. Conclusions: This case supports the feasibility of integrating point-of-care 3D biomodeling with cyanoacrylate as a coadjuvant to microplate fixation in selected comminuted frontal sinus fractures to enhance fragment handling and contour restoration.<\/jats:p>","DOI":"10.3390\/jcm15052057","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T08:58:45Z","timestamp":1773046725000},"page":"2057","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Digitally Guided Frontal Sinus Fracture Fixation: A Point-of-Care \u201cIn-House\u201d Biomodel Protocol with Cyanoacrylate-Assisted Fragment Stabilization"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3329-4896","authenticated-orcid":false,"given":"Manuel","family":"Tousidonis","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"},{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Advanced Planning and 3D Manufacturing Unit (UPAM3D), Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Dr. Esquerdo 46, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9357-7102","authenticated-orcid":false,"given":"Saad","family":"Khayat","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2606-8997","authenticated-orcid":false,"given":"Cristina","family":"Maza-Muela","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"},{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocio","family":"Franco-Herrera","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gregorio Mara\u00f1\u00f3n University Hospital, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4051-2759","authenticated-orcid":false,"given":"Ruben","family":"P\u00e9rez-Ma\u00f1anes","sequence":"additional","affiliation":[{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Advanced Planning and 3D Manufacturing Unit (UPAM3D), Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Dr. Esquerdo 46, 28007 Madrid, Spain"},{"name":"Surgery Department, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose-Antonio","family":"Calvo-Haro","sequence":"additional","affiliation":[{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Advanced Planning and 3D Manufacturing Unit (UPAM3D), Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Dr. Esquerdo 46, 28007 Madrid, Spain"},{"name":"Surgery Department, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria J.","family":"Troulis","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA"},{"name":"Harvard School of Dental Medicine and Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9869-9240","authenticated-orcid":false,"given":"Carlos","family":"Navarro-Cuellar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"},{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Surgery Department, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose-Ignacio","family":"Salmeron","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"},{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Surgery Department, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3576-6498","authenticated-orcid":false,"given":"Santiago","family":"Ochandiano","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Gregorio Mara\u00f1on University Hospital, 28007 Madrid, Spain"},{"name":"Gregorio Mara\u00f1\u00f3n Research Institute, 28007 Madrid, Spain"},{"name":"Surgery Department, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1055\/s-0038-1675560","article-title":"Frontal Sinus Fractures: Management and Complications","volume":"12","author":"Jing","year":"2019","journal-title":"Craniomaxillofac. 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