{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:07Z","timestamp":1773273607550,"version":"3.50.1"},"reference-count":46,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["RC 2026"],"award-info":[{"award-number":["RC 2026"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: In Southern Italy, metabolic dysfunction-associated fatty liver disease (MASLD) is rising despite adherence to traditional Mediterranean diets. Accurate assessment of physical activity (PA) and sedentary behavior is critical for effective non-pharmacological management but remains methodologically challenging. Methods: We compared subjective and objective PA measures in 133 adults (mean age 49.0 \u00b1 9.8 years; BMI 35.7 \u00b1 4.9 kg\/m2) with moderate-to-severe MASLD. Participants completed the International Physical Activity Questionnaire\u2013Short Form (IPAQ-SF) and wore an ActiGraph GT9X wrist accelerometer for seven days. Results: The IPAQ-SF significantly underestimated moderate PA by 865 min\/week (p &lt; 0.001) and reported 33.16 \u00b1 14.78 min\/week of vigorous activity not detected by accelerometry. Sedentary time was slightly underestimated (0.45 h\/day, p = 0.05), with better overall agreement. Stratified analyses showed significant underestimation of sedentary behavior among women and participants &lt;50 years. Spearman correlations were weak (rho = 0.14 for moderate PA; rho = 0.36 for sedentary behavior). Bland\u2013Altman plots confirmed poor agreement for moderate PA but acceptable limits for sedentary estimates. Conclusions: In high-risk Southern Italian populations with MASLD, reliance on self-reported PA may lead to inaccurate clinical guidance. Integrating objective monitoring with subjective tools is essential to deliver precise, individualized exercise prescriptions beyond generic \u201cmove more\u201d recommendations.<\/jats:p>","DOI":"10.3390\/jcm15062126","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:00:37Z","timestamp":1773219637000},"page":"2126","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beyond \u201cMove More\u201d: Combined Physical Activity and Sedentary Behavior Assessment in Individuals with MASLD from Southern Italy"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9319-5422","authenticated-orcid":false,"given":"Antonella","family":"Bianco","sequence":"first","affiliation":[{"name":"Laboratory of Movement and Wellness, National Institute of Gastroenterology IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Beatrice","family":"Bagnato","sequence":"additional","affiliation":[{"name":"Laboratory of Movement and Wellness, National Institute of Gastroenterology IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3697-0127","authenticated-orcid":false,"given":"Isabella","family":"Franco","sequence":"additional","affiliation":[{"name":"Laboratory of Movement and Wellness, National Institute of Gastroenterology IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Verrelli","sequence":"additional","affiliation":[{"name":"Laboratory of Movement and Wellness, National Institute of Gastroenterology IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8650-348X","authenticated-orcid":false,"given":"Caterina","family":"Bonfiglio","sequence":"additional","affiliation":[{"name":"Data Science, National Institute of Gastroenterology IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"(2024). 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