{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:52:08Z","timestamp":1785462728007,"version":"3.56.0"},"reference-count":24,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Erythema gyratum repens (EGR) is a rare figurate erythema strongly associated with internal malignancy and recognized as one of the most specific cutaneous paraneoplastic syndromes. Its recognition is clinically important, as it frequently precedes the diagnosis of an underlying neoplasm. We report the case of an 80-year-old woman who presented to the emergency department with a rapidly progressive, intensely pruritic eruption displaying a characteristic concentric \u201cwood-grain\u201d pattern. Laboratory evaluation revealed iron-deficiency anemia. Contrast-enhanced computed tomography identified a right-sided colonic mass, and colonoscopy with biopsy confirmed adenocarcinoma of the cecum. The patient underwent elective laparoscopic right hemicolectomy with complete tumor resection (pT3N0, microsatellite stable). Following surgery, the cutaneous lesions resolved completely and did not recur during follow-up. This case highlights erythema gyratum repens as a clinically relevant early marker of colorectal cancer and emphasizes the importance of prompt recognition of this distinctive dermatosis to trigger urgent and comprehensive malignancy screening, enabling timely diagnosis and definitive treatment.<\/jats:p>","DOI":"10.3390\/jcm15072789","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:03:47Z","timestamp":1775563427000},"page":"2789","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cutaneous Manifestations as a Sentinel of Colorectal Cancer: A Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"B\u00e1rbara","family":"Marinho","sequence":"first","affiliation":[{"name":"Digestive and Extradigestive Service, Surgery Department, Centro Hospitalar Universit\u00e1rio de Santo Ant\u00f3nio, Unidade Local de Sa\u00fade de Santo Ant\u00f3nio, 4099-001 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gl\u00f3ria","family":"Velho","sequence":"additional","affiliation":[{"name":"Dermatology Service, Centro Hospitalar Universit\u00e1rio de Santo Ant\u00f3nio, Unidade Local de Sa\u00fade de Santo Ant\u00f3nio, 4099-001 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5704-8895","authenticated-orcid":false,"given":"Marisa D.","family":"Santos","sequence":"additional","affiliation":[{"name":"Digestive and Extradigestive Service, Surgery Department, Centro Hospitalar Universit\u00e1rio de Santo Ant\u00f3nio, Unidade Local de Sa\u00fade de Santo Ant\u00f3nio, 4099-001 Porto, Portugal"},{"name":"Colorectal Surgery Unit, Digestive and Extradigestive Surgery Service, Centro Hospitalar Universit\u00e1rio de Santo Ant\u00f3nio, Unidade Local de Sa\u00fade de Santo Ant\u00f3nio, 4099-001 Porto, Portugal"},{"name":"ICBAS\u2014School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"},{"name":"UMIB (Unit for Multidisciplinary Research in Biomedicine), ICBAS\u2014School of Medicine and Biomedical Sciences, University of Porto, 4045-313 Porto, Portugal"},{"name":"ITR (Laboratory for Integrative and Translational Research in Population Health), 4050-600 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.4065\/mcp.2010.0099","article-title":"Paraneoplastic syndromes: An approach to diagnosis and treatment","volume":"85","author":"Pelosof","year":"2010","journal-title":"Mayo Clin. 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Dermatol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/7\/2789\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:24:15Z","timestamp":1775564655000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/7\/2789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,7]]},"references-count":24,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["jcm15072789"],"URL":"https:\/\/doi.org\/10.3390\/jcm15072789","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,7]]}}}