{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:16:32Z","timestamp":1785428192022,"version":"3.56.0"},"reference-count":208,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["503\/1-152-01\/503-11-001"],"award-info":[{"award-number":["503\/1-152-01\/503-11-001"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"award":["503\/1-152-01\/503-11-001"],"award-info":[{"award-number":["503\/1-152-01\/503-11-001"]}],"id":[{"id":"https:\/\/ror.org\/02t4ekc95","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Dermatomyositis (DM) is a rare, autoimmune inflammatory myopathy characterized by a heterogeneous clinical course and complex etiopathogenesis. Although classically defined by the coexistence of muscle inflammation and distinctive skin lesions, DM frequently presents as a systemic disease, and, in some patients, cutaneous manifestations may precede muscle involvement or represent the sole clinical feature. The spectrum of skin lesions in DM is broad and includes pathognomonic, characteristic, rare, or atypical manifestations, ranging from classic Gottron\u2019s sign and heliotrope rash to uncommon subtypes such as vesiculobullous dermatomyositis, Wong-type dermatomyositis, or flagellate dermatitis. Particular cutaneous phenotypes often correlate with distinct clinical subtypes, autoantibody profiles, systemic involvement, and prognosis. The diversity of dermatological presentations and their resemblance to other dermatoses may delay accurate diagnosis, especially in amyopathic and hypomyopathic forms of the disease. The aim of this review is to comprehensively discuss the wide spectrum of cutaneous manifestations of dermatomyositis, emphasize less recognized and rare dermatological clinical presentations, and highlight their diagnostic and prognostic significance. However, histopathological examination may support the diagnostic process in challenging cases. Early identification of characteristic skin lesions remains crucial for prompt diagnosis, appropriate screening for systemic complications and malignancy, and optimal management. Close interdisciplinary cooperation among dermatologists, rheumatologists, and other specialists is essential to ensure accurate diagnosis and improve outcomes in patients with dermatomyositis.<\/jats:p>","DOI":"10.3390\/jcm15082874","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T09:08:12Z","timestamp":1775812092000},"page":"2874","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Spectrum of Cutaneous Manifestations in Dermatomyositis: A Comprehensive Review"],"prefix":"10.3390","volume":"15","author":[{"given":"Magdalena","family":"Kutwin","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Medical University of Lodz, Haller sq. 1, 90-647 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Karp","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Medical University of Lodz, Haller sq. 1, 90-647 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelina","family":"K\u0105dziela","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Medical University of Lodz, Haller sq. 1, 90-647 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Siennicka","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Medical University of Lodz, Haller sq. 1, 90-647 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4548-3080","authenticated-orcid":false,"given":"Agnieszka","family":"\u017bebrowska","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Medical University of Lodz, Haller sq. 1, 90-647 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jaut.2013.11.005","article-title":"The clinical features, diagnosis and classification of dermatomyositis","volume":"48\u201349","author":"Iaccarino","year":"2014","journal-title":"J. Autoimmun."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00405-006-0217-5","article-title":"Paraneoplastic syndromes in patients with primary head and neck cancer","volume":"264","author":"Ferlito","year":"2007","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM197502202920807","article-title":"Polymyositis and dermatomyositis (second of two parts)","volume":"292","author":"Bohan","year":"1975","journal-title":"N. Engl. J. Med."},{"key":"ref_4","unstructured":"(2024, April 19). Clinical Manifestations of Dermatomyositis and Polymyositis in Adults\u2014UpToDate. Available online: https:\/\/www.uptodate.com\/contents\/clinical-manifestations-of-dermatomyositis-and-polymyositis-in-adults."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1056\/NEJM197502132920706","article-title":"Polymyositis and dermatomyositis (first of two parts)","volume":"292","author":"Bohan","year":"1975","journal-title":"N. Engl. J. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1136\/annrheumdis-2017-211468","article-title":"2017 European League Against Rheumatism\/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups","volume":"76","author":"Lundberg","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"ref_7","first-page":"409","article-title":"Dermatomyositis and malignancy","volume":"65","author":"Hu","year":"2019","journal-title":"Can. Fam. Physician"},{"key":"ref_8","unstructured":"(2025, March 06). Malignancy in Dermatomyositis and Polymyositis\u2014UpToDate |PDF|. Available online: https:\/\/www.scribd.com\/document\/943652387\/Malignancy-in-Dermatomyositis-and-Polymyositis-UpToDate."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.autrev.2009.11.006","article-title":"The geoepidemiology of autoimmune muscle disease","volume":"9","author":"Prieto","year":"2010","journal-title":"Autoimmun. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1097\/00002281-200211000-00005","article-title":"Clinical outcomes in juvenile dermatomyositis","volume":"14","author":"Ramanan","year":"2002","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"183","DOI":"10.5114\/dr.2015.51919","article-title":"Special papersDiagnostic and therapeutic advances in dermatomyositis","volume":"102","author":"Samotij","year":"2015","journal-title":"Dermatol. Rev.\/Przegl\u0105d Dermatol."},{"key":"ref_12","first-page":"1198","article-title":"Juvenile dermatomyositis at diagnosis: Clinical characteristics of 79 children","volume":"6","author":"Pachman","year":"1998","journal-title":"J. Rheumatol."},{"key":"ref_13","first-page":"1329","article-title":"Incidence of polymyositis-dermatomyositis: A 20-year study of hospital diagnosed cases in Allegheny County, PA 1963\u20131982","volume":"10","author":"Oddis","year":"1990","journal-title":"J. Rheumatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/joim.12451","article-title":"Myositis-specific autoantibodies: An important tool to support diagnosis of myositis","volume":"280","author":"Betteridge","year":"2016","journal-title":"J. Intern. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/BOR.0b013e3282f01a8c","article-title":"Autoantibodies in idiopathic inflammatory myopathy: An update on clinical and pathophysiological significance","volume":"19","author":"Mimori","year":"2007","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1093\/rheumatology\/kem045","article-title":"Anti-synthetase syndrome: A new autoantibody to phenylalanyl transfer RNA synthetase (anti-Zo) associated with polymyositis and interstitial pneumonia","volume":"46","author":"Betteridge","year":"2007","journal-title":"Rheumatology"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.4049\/jimmunol.162.4.2315","article-title":"Anti-KS: Identification of autoantibodies to asparaginyl-transfer RNA synthetase associated with interstitial lung disease","volume":"162","author":"Hirakata","year":"1999","journal-title":"J. Immunol."},{"key":"ref_18","unstructured":"(2026, January 18). Autoantibodies to Aminoacyl-Transfer RNA Synthetases for Isoleucine and Glycine. Two Additional Synthetases Are Antigenic in Myositis\u2014PubMed [Internet], Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/2307838\/."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1084\/jem.163.5.1281","article-title":"Autoantibodies against alanyl-tRNA synthetase and tRNAAla coexist and are associated with myositis","volume":"163","author":"Bunn","year":"1986","journal-title":"J. Exp. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s11926-013-0349-8","article-title":"Clinical heterogeneity and outcomes of antisynthetase syndrome","volume":"15","author":"Hervier","year":"2013","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1097\/BOR.0000000000000548","article-title":"New insights in myositis-specific autoantibodies","volume":"30","author":"Ghirardello","year":"2018","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/0002-9343(84)90677-6","article-title":"Polymyositis and interstitial lung disease in a patient with anti-Jo1 prototype","volume":"76","author":"Wasicek","year":"1984","journal-title":"Am. J. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1111\/bjd.15607","article-title":"The pathogenesis of dermatomyositis","volume":"179","author":"Thompson","year":"2018","journal-title":"Br. J. Dermatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jaad.2019.06.1309","article-title":"Dermatomyositis: Clinical features and pathogenesis","volume":"82","author":"DeWane","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0190-9622(89)70074-8","article-title":"Cutaneous changes of dermatomyositis precede muscle weakness","volume":"20","author":"Giustina","year":"1989","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s12016-015-8496-5","article-title":"Cutaneous Manifestations in Dermatomyositis: Key Clinical and Serological Features-a Comprehensive Review","volume":"51","author":"Muro","year":"2016","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_27","first-page":"69","article-title":"Dermatomyositis: Nailfold capillaroscopy patterns and a general survey","volume":"33","author":"Trevisan","year":"2024","journal-title":"Acta Dermatovenerol. Alp. Pannonica Adriat."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s12016-017-8652-1","article-title":"Cutaneous Manifestations of Dermatomyositis: A Comprehensive Review","volume":"53","author":"Mainetti","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.clindermatol.2006.07.001","article-title":"Dermatomyositis","volume":"24","author":"Callen","year":"2006","journal-title":"Clin. Dermatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1097\/00002281-200311000-00006","article-title":"Skin involvement in dermatomyositis","volume":"15","author":"Dugan","year":"2003","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1684\/ejd.2020.3761","article-title":"The polymorphous spectrum of dermatomyositis: Classic features, newly described skin lesions, and rare variants","volume":"30","author":"Didona","year":"2020","journal-title":"Eur. J. Dermatol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"42","DOI":"10.5114\/reum.2022.114109","article-title":"Nailfold capillaroscopy changes with disease activity in patients with inflammatory myositis including overlap myositis, pure dermatomyositis, and pure polymyositis","volume":"60","author":"Shenavandeh","year":"2022","journal-title":"Reumatologia"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s00403-024-03521-z","article-title":"Nailfold microscopy in adult-onset dermatomyositis in association with myositis antibodies","volume":"317","author":"Flatley","year":"2024","journal-title":"Arch. Dermatol. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1001\/archdermatol.2011.2052","article-title":"Calcinosis cutis occurring in association with autoimmune connective tissue disease: The Mayo Clinic experience with 78 patients, 1996\u20132009","volume":"148","author":"Balin","year":"2012","journal-title":"Arch. Dermatol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.jaad.2006.05.005","article-title":"Childhood acquired lipodystrophy: A retrospective study","volume":"55","author":"Pope","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0190-9622(07)80015-6","article-title":"Vesicle formation in dermatomyositis associated with gynecologic malignancies","volume":"34","author":"Kubo","year":"1996","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/00000372-199804000-00012","article-title":"Vesiculo-bullous dermatomyositis","volume":"20","author":"McCollough","year":"1998","journal-title":"Am. J. Dermatopathol."},{"key":"ref_38","first-page":"135","article-title":"Gingival telangiectases: An underappreciated physical sign of juvenile dermatomyositis","volume":"1","author":"Ghali","year":"1999","journal-title":"Arch. Dermatol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2147\/ITT.S381472","article-title":"Dermatomyositis: Practical Guidance and Unmet Needs","volume":"13","author":"Cassard","year":"2024","journal-title":"Immunotargets Ther."},{"key":"ref_40","first-page":"15","article-title":"Implications in the difference of anti-Mi-2 and -p155\/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara","volume":"4","author":"Petri","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/art.33403","article-title":"Myositis-specific anti-155\/140 autoantibodies target transcription intermediary factor 1 family proteins","volume":"64","author":"Fujimoto","year":"2012","journal-title":"Arthritis Rheum."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1002\/art.38093","article-title":"Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1\u03b3","volume":"65","author":"Fiorentino","year":"2013","journal-title":"Arthritis Rheum."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s11926-018-0733-5","article-title":"Dermatomyositis Clinical and Pathological Phenotypes Associated with Myositis-Specific Autoantibodies","volume":"20","author":"Wolstencroft","year":"2018","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1001\/jamadermatol.2016.1429","article-title":"Ovoid Palatal Patch in Dermatomyositis: A Novel Finding Associated With Anti-TIF1\u03b3 (p155) Antibodies","volume":"152","author":"Bernet","year":"2016","journal-title":"JAMA Dermatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.jaad.2014.12.009","article-title":"Distinctive cutaneous and systemic features associated with antitranscriptional intermediary factor-1\u03b3 antibodies in adults with dermatomyositis","volume":"72","author":"Fiorentino","year":"2015","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.autrev.2017.05.003","article-title":"Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology","volume":"16","author":"Suzuki","year":"2017","journal-title":"Autoimmun. Rev."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1097\/BOR.0000000000000329","article-title":"Recent advances in dermatomyositis-specific autoantibodies","volume":"2","author":"Fujimoto","year":"2016","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12016-015-8510-y","article-title":"A Comprehensive Overview on Myositis-Specific Antibodies: New and Old Biomarkers in Idiopathic Inflammatory Myopathy","volume":"52","author":"Satoh","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1002\/art.21023","article-title":"Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis","volume":"52","author":"Sato","year":"2005","journal-title":"Arthritis Rheum."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/art.42521","article-title":"Clinical Images: Multiple punched-out ulcerations on the abdomen in anti-melanoma differentiation-associated gene 5 dermatomyositis","volume":"76","author":"Mutoh","year":"2024","journal-title":"Arthritis Rheumatol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00403-016-1704-1","article-title":"Specific autoantibodies in dermatomyositis: A helpful tool to classify different clinical subsets","volume":"309","author":"Merlo","year":"2017","journal-title":"Arch. Dermatol. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/DAD.0b013e31818520e1","article-title":"Dermatomyositis: A clinicopathological study of 40 patients","volume":"31","author":"Smith","year":"2009","journal-title":"Am. J. Dermatopathol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/cup.14203","article-title":"Do histopathological features correlate with systemic manifestations in dermatomyositis? Analysis of 42 skin biopsy specimens from 22 patients","volume":"49","author":"Shakshouk","year":"2022","journal-title":"J. Cutan. Pathol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(99)05157-0","article-title":"Dermatomyositis","volume":"355","author":"Callen","year":"2000","journal-title":"Lancet"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2","DOI":"10.12968\/hmed.2012.73.Sup2.C18","article-title":"Dermatomyositis","volume":"73","author":"Mahil","year":"2012","journal-title":"Br. J. Hosp. Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jaad.2019.05.105","article-title":"Dermatomyositis: Diagnosis and treatment","volume":"82","author":"Waldman","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.21037\/apm-19-650","article-title":"The quest for diagnostic approaches of cardiac involvement in polymyositis and dermatomyositis","volume":"9","author":"Liu","year":"2020","journal-title":"Ann. Palliat. Med."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00005382-199203000-00006","article-title":"Pulmonary and cardiac manifestations of polymyositis-dermatomyositis","volume":"7","author":"Schwarz","year":"1992","journal-title":"J. Thorac. Imaging"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ehpc.2017.03.005","article-title":"Cardiac transplantation in dermatomyositis: A case report and literature review","volume":"8","author":"Bae","year":"2017","journal-title":"Human Pathol. Case Rep."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1055\/s-2007-985666","article-title":"Pulmonary complications of polymyositis and dermatomyositis","volume":"28","author":"Fathi","year":"2007","journal-title":"Semin. Respir. Crit. Care Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s12016-020-08822-5","article-title":"Interstitial Lung Disease in Anti-MDA5 Positive Dermatomyositis","volume":"60","author":"Wu","year":"2021","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1055\/s-0034-1371528","article-title":"Pulmonary manifestations of polymyositis\/dermatomyositis","volume":"35","author":"Hallowell","year":"2014","journal-title":"Semin. Respir. Crit. Care Med."},{"key":"ref_63","first-page":"165","article-title":"Prognosis of dysphagia in dermatomyositis","volume":"37","author":"Muro","year":"2019","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Mugii, N., Hasegawa, M., Matsushita, T., Hamaguchi, Y., Oohata, S., Okita, H., Yahata, T., Someya, F., Inoue, K., and Murano, S. (2016). Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0154746"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/nmo.14572","article-title":"A systematic review and meta-analysis on the prevalence and clinical characteristics of dysphagia in patients with dermatomyositis","volume":"35","author":"Cheng","year":"2023","journal-title":"Neurogastroenterol. Motil."},{"key":"ref_66","first-page":"782","article-title":"Clinical features and outcome in a Danish cohort of juvenile dermatomyositis patients","volume":"28","author":"Mathiesen","year":"2010","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/art.11122","article-title":"NIAMS Juvenile DM Registry Physician Referral Group. US incidence of juvenile dermatomyositis, 1995\u20131998: Results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry","volume":"15","author":"Mendez","year":"2003","journal-title":"Arthritis Rheum."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4078\/jrd.2022.29.1.14","article-title":"Juvenile Dermatomyositis","volume":"29","author":"Rhim","year":"2022","journal-title":"J. Rheum. Dis."},{"key":"ref_69","first-page":"192","article-title":"The arthritis of inflammatory childhood myositis syndromes","volume":"28","author":"Tse","year":"2001","journal-title":"J. Rheumatol."},{"key":"ref_70","first-page":"1031","article-title":"A Brazilian registry of juvenile dermatomyositis: Onset features and classification of 189 cases","volume":"27","author":"Sato","year":"2009","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/acr.23338","article-title":"Assessment of Microvascular Abnormalities by Nailfold Capillaroscopy in Juvenile Dermatomyositis After Medium- to Long-Term Followup","volume":"70","author":"Barth","year":"2018","journal-title":"Arthritis Care Res."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1365-263X.2010.01074.x","article-title":"Oral manifestations as important symptoms for juvenile dermatomyositis early diagnosis: A case report","volume":"21","year":"2011","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/1529-0131(200003)43:3<541::AID-ANR9>3.0.CO;2-T","article-title":"Medium- and long-term functional outcomes in a multicenter cohort of children with juvenile dermatomyositis","volume":"43","author":"Huber","year":"2000","journal-title":"Arthritis Rheum."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/rheumatology\/kel099","article-title":"The Juvenile Dermatomyositis National Registry and Repository (UK and Ireland)\u2014Clinical characteristics of children recruited within the first 5 yr","volume":"45","author":"McCann","year":"2006","journal-title":"Rheumatology"},{"key":"ref_75","first-page":"87","article-title":"Calcinosis in juvenile dermatomyositis mimicking cold abscess","volume":"29","author":"Nagar","year":"2016","journal-title":"Natl. Med. J. India"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/S0140-6736(08)60955-1","article-title":"Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood","volume":"371","author":"Feldman","year":"2008","journal-title":"Lancet"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/MPH.0b013e3181bf29a2","article-title":"Juvenile dermatomyositis as a paraneoplastic phenomenon: An update","volume":"32","author":"Morris","year":"2010","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/nan.12528","article-title":"Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: Analysis by myositis autoantibody and pathological features","volume":"45","author":"Yasin","year":"2019","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/MD.0b013e31816bc604","article-title":"Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity","volume":"87","author":"Bingham","year":"2008","journal-title":"Medicine"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jaut.2017.06.007","article-title":"Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort","volume":"84","author":"Tansley","year":"2017","journal-title":"J. Autoimmun."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/ar4198","article-title":"Adult and juvenile dermatomyositis: Are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms?","volume":"15","author":"Tansley","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5070\/D328659719","article-title":"Characteristics of patients with juvenile dermatomyositis from 2001-2021 at a tertiary care center","volume":"28","author":"Simmons","year":"2022","journal-title":"Dermatol. Online J."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1001\/archdermatol.2009.328","article-title":"Incidence of Dermatomyositis and Clinically Amyopathic Dermatomyositis: A Population-Based Study in Olmsted County, Minnesota","volume":"146","author":"Bendewald","year":"2010","journal-title":"Arch. Dermatol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/BOR.0b013e32833f1987","article-title":"Clinically amyopathic dermatomyositis","volume":"22","author":"Sato","year":"2010","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11926-014-0465-0","article-title":"Amyopathic dermatomyositis: Definitions, diagnosis, and management","volume":"16","author":"Bailey","year":"2014","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.jaad.2005.10.041","article-title":"A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis sin\u00e9 myositis): A missing link within the spectrum of the idiopathic inflammatory myopathies","volume":"54","author":"Gerami","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/rheumatology\/keh723","article-title":"Interstitial lung disease in patients with polymyositis, dermatomyositis and amyopathic dermatomyositis","volume":"44","author":"Kang","year":"2005","journal-title":"Rheumatology"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0190-9622(08)80589-0","article-title":"Amyopathic dermatomyositis","volume":"26","author":"Grau","year":"1992","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3760\/cma.j.issn.0366-6999.2010.05.002","article-title":"Predictive factors and unfavourable prognostic factors of interstitial lung disease in patients with polymyositis or dermatomyositis: A retrospective study","volume":"123","author":"Ji","year":"2010","journal-title":"Chin. Med. J."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/cup.14691","article-title":"Clinically amyopathic dermatomyositis: Clinical, laboratory, and histopathological features","volume":"51","author":"Wang","year":"2024","journal-title":"J. Cutan. Pathol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1093\/rheumatology\/keq153","article-title":"Anti-MDA5 and anti-TIF1-gamma antibodies have clinical significance for patients with dermatomyositis","volume":"49","author":"Hoshino","year":"2010","journal-title":"Rheumatology"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/03009740802687455","article-title":"Association of distinct clinical subsets with myositis-specific autoantibodies towards anti-155\/140-kDa polypeptides, anti-140-kDa polypeptides, and anti-aminoacyl tRNA synthetases in Japanese patients with dermatomyositis: A single-centre, cross-sectional study","volume":"38","author":"Fujikawa","year":"2009","journal-title":"Scand. J. Rheumatol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"89","DOI":"10.5387\/fms.2018-01","article-title":"Anti-MDA5 antibody-positive hypomyopathic dermatomyositis complicated with pneumomediastinum","volume":"64","author":"Yashiro","year":"2018","journal-title":"Fukushima J. Med. Sci."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1056\/NEJMc1900045","article-title":"Tofacitinib in Amyopathic Dermatomyositis-Associated Interstitial Lung Disease","volume":"381","author":"Chen","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"151959","DOI":"10.1016\/j.semarthrit.2022.151959","article-title":"Management of MDA-5 antibody positive clinically amyopathic dermatomyositis associated interstitial lung disease: A systematic review","volume":"53","author":"McPherson","year":"2022","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1002\/art.22862","article-title":"Identification of a novel autoantibody directed against small ubiquitin-like modifier activating enzyme in dermatomyositis","volume":"56","author":"Betteridge","year":"2007","journal-title":"Arthritis Rheum."},{"key":"ref_97","doi-asserted-by":"crossref","unstructured":"Hamaguchi, Y., Fujimoto, M., Matsushita, T., Kaji, K., Komura, K., Hasegawa, M., Kodera, M., Muroi, E., Fujikawa, K., and Seishima, M. (2013). Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: Heterogeneity within the syndrome. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0060442"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/art.1780380111","article-title":"Use of magnetic resonance imaging and P-31 magnetic resonance spectroscopy to detect and quantify muscle dysfunction in the amyopathic and myopathic variants of dermatomyositis","volume":"38","author":"Park","year":"1995","journal-title":"Arthritis Rheum."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s40257-016-0199-z","article-title":"Amyopathic Dermatomyositis: A Concise Review of Clinical Manifestations and Associated Malignancies","volume":"17","author":"Udkoff","year":"2016","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1054\/bjoc.2001.1699","article-title":"Risk of cancer in patients with dermatomyositis or polymyositis, and follow-up implications: A Scottish population-based cohort study","volume":"85","author":"Stockton","year":"2001","journal-title":"Br. J. Cancer"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/0973-029X.164539","article-title":"Unusual cases of carcinoma of palatine tonsil","volume":"19","author":"Chikkannaiah","year":"2015","journal-title":"J. Oral Maxillofac. Pathol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.ad.2013.11.007","article-title":"Paraneoplastic dermatomyositis: A study of 12 cases","volume":"105","author":"Requena","year":"2014","journal-title":"Actas Dermo-Sifiliogr."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"509354","DOI":"10.1155\/2013\/509354","article-title":"Clinical features of inflammatory myopathies and their association with malignancy: A systematic review in asian population","volume":"2013","author":"Ungprasert","year":"2013","journal-title":"ISRN Rheumatol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0140-6736(00)03540-6","article-title":"Frequency of specific cancer types in dermatomyositis and polymyositis: A population-based study","volume":"357","author":"Hill","year":"2001","journal-title":"Lancet"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/ar2987","article-title":"Cancer risks of dermatomyositis and polymyositis: A nationwide cohort study in Taiwan","volume":"12","author":"Chen","year":"2010","journal-title":"Arthritis Res. Ther."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/MD.0b013e31819da352","article-title":"Factors associated with underlying malignancy in a retrospective cohort of 121 patients with dermatomyositis","volume":"88","author":"Fardet","year":"2009","journal-title":"Medicine"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.anorl.2010.10.007","article-title":"Paraneoplastic dermatomyositis accompanying nasopharyngeal carcinoma: Diagnosis, treatment and prognosis","volume":"128","author":"Chakroun","year":"2011","journal-title":"Eur. Ann. Otorhinolaryngol. Head Neck Dis."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"e949810","DOI":"10.12659\/AJCR.949810","article-title":"Paraneoplastic Dermatomyositis in Patient with Primary Biliary Cirrhosis and Hepatocellular Carcinoma: A Case Report","volume":"26","author":"Neycheva","year":"2025","journal-title":"Am. J. Case Rep."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5114\/dr.2021.107278","article-title":"Dermatomyositis. Diagnostic and therapeutic recommendations of the Polish Dermatological Society","volume":"108","author":"Reich","year":"2021","journal-title":"Dermatol. Rev.\/Przegl\u0105d Dermatol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/s41584-023-01045-w","article-title":"International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: An International Myositis Assessment and Clinical Studies Group (IMACS) initiative","volume":"19","author":"Oldroyd","year":"2023","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1365-2230.2009.03216.x","article-title":"Defining cancer risk in dermatomyositis. Part I","volume":"34","author":"Madan","year":"2009","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/1203475416665601","article-title":"Risk of Malignancy in Dermatomyositis and Polymyositis","volume":"21","author":"Qiang","year":"2017","journal-title":"J. Cutan. Med. Surg."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"E21733","DOI":"10.1097\/MD.0000000000021733","article-title":"Malignancy in dermatomyositis: A retrospective paired case-control study of 202 patients from Central China","volume":"99","author":"Chang","year":"2020","journal-title":"Medicine"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/25785826.2018.1531188","article-title":"Clinical significance of myositis-specific autoantibodies","volume":"41","author":"Nakashima","year":"2018","journal-title":"Immunol. Med."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1002\/art.34579","article-title":"Anti-p155 autoantibodies as a diagnostic marker for cancer-associated dermatomyositis: Comment on the article by Trallero-Aragu\u00e1s et al","volume":"64","author":"Rhee","year":"2012","journal-title":"Arthritis Rheum."},{"key":"ref_116","doi-asserted-by":"crossref","unstructured":"Aussy, A., Boyer, O., and Cordel, N. (2017). Dermatomyositis and Immune-Mediated Necrotizing Myopathies: A Window on Autoimmunity and Cancer. Front. Immunol., 21.","DOI":"10.3389\/fimmu.2017.00992"},{"key":"ref_117","first-page":"253","article-title":"Paraneoplastic Anti-Tif1-gamma Autoantibody-positive Dermatomyositis as Clinical Presentation of Hepatocellular Carcinoma Recurrence","volume":"11","author":"Ferronato","year":"2023","journal-title":"J. Clin. Transl. Hepatol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.autrev.2014.08.011","article-title":"Four dermatomyositis-specific autoantibodies-anti-TIF1\u03b3, anti-NXP2, anti-SAE and anti-MDA5-in adult and juvenile patients with idiopathic inflammatory myopathies in a Hungarian cohort","volume":"13","author":"Bodoki","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/annrheumdis-2011-200697","article-title":"Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: Possible association with malignancy","volume":"71","author":"Ichimura","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/cup.13442","article-title":"Clinical factors associated with cutaneous histopathologic findings in dermatomyositis","volume":"46","author":"Wolstencroft","year":"2019","journal-title":"J. Cutan. Pathol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.autrev.2023.103464","article-title":"Clinical features of dermatomyositis patients with anti-TIF1 antibodies: A case based comprehensive review","volume":"22","author":"Kilinc","year":"2023","journal-title":"Autoimmun. Rev."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2340\/00015555-0455","article-title":"Bullous dermatomyositis: A marker of poor prognosis and aggressive internal malignancy?","volume":"88","author":"Zangrilli","year":"2008","journal-title":"Acta Derm.-Venereol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jaad.2010.09.016","article-title":"The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): A retrospective study","volume":"65","author":"Fiorentino","year":"2011","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1002\/art.23960","article-title":"Predicting the course of juvenile dermatomyositis: Significance of early clinical and laboratory features","volume":"58","author":"Stringer","year":"2008","journal-title":"Arthritis Rheum."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"432","DOI":"10.21037\/atm-20-5215","article-title":"Dermatomyositis and malignancy: Should all patients with dermatomyositis undergo malignancy screening?","volume":"5","author":"Khanna","year":"2021","journal-title":"Ann. Transl. Med."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3233\/JND-180308","article-title":"Current Classification and Management of Inflammatory Myopathies","volume":"5","author":"Schmidt","year":"2018","journal-title":"J. Neuromuscul. Dis."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0011-5029(87)90022-8","article-title":"Dermatomyositis","volume":"33","author":"Callen","year":"1987","journal-title":"Disease-a-Month"},{"key":"ref_128","first-page":"1565","article-title":"Dermatomyositis","volume":"64","author":"Koler","year":"2001","journal-title":"Am. Fam. Physician"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s40674-023-00206-y","article-title":"Systemic sclerosis associated myopathy: How to treat","volume":"9","author":"Milisenda","year":"2023","journal-title":"Curr. Treat. Opt. Rheumatol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0738-081X(88)90046-6","article-title":"A rheumatologist\u2019s view of polymyositis\/dermatomyositis: Extracutaneous and extramuscular involvement and overlap syndromes","volume":"6","author":"Romans","year":"1988","journal-title":"Clin. Dermatol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0002-9343(93)90148-I","article-title":"Drug therapy of the idiopathic inflammatory myopathies: Predictors of response to prednisone, azathioprine, and methotrexate and a comparison of their efficacy","volume":"94","author":"Joffe","year":"1993","journal-title":"Am. J. Med."},{"key":"ref_132","doi-asserted-by":"crossref","unstructured":"Ha, J.W., Park, Y.B., and Lee, S.W. (2023). Overlap Syndrome Consisting of Polymyositis\/Dermatomyositis and ANCA-Associated Vasculitis According to the 2022 ACR\/EULAR Criteria for Vasculitis: A Korean Single-Centre Study. J. Clin. Med., 12.","DOI":"10.3390\/jcm12216748"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.jaad.2008.05.034","article-title":"Dermatomyositis induced by drug therapy: A review of case reports","volume":"59","author":"Seidler","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"152478","DOI":"10.1016\/j.semarthrit.2024.152478","article-title":"Investigating the disparities among drug categories in drug-induced dermatomyositis: A systematic review","volume":"67","author":"Yu","year":"2024","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1001\/jamadermatol.2023.5418","article-title":"Causes and Clinical Presentation of Drug-Induced Dermatomyositis: A Systematic Review","volume":"160","author":"Caravan","year":"2024","journal-title":"JAMA Dermatol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s00296-017-3658-9","article-title":"Atorvastatin-induced dermatomyositis","volume":"37","author":"Oztas","year":"2017","journal-title":"Rheumatol. Int."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1080\/1744666X.2018.1440206","article-title":"Statin-induced myalgia and myositis: An update on pathogenesis and clinical recommendations","volume":"14","author":"Milisenda","year":"2018","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"E19741","DOI":"10.1097\/MD.0000000000019741","article-title":"A case report of fulminant cytokine release syndrome complicated by dermatomyositis after the combination therapy with immune checkpoint inhibitors","volume":"99","author":"Ohira","year":"2020","journal-title":"Medicine"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s13555-020-00396-6","article-title":"Toripalimab-Induced Dermatomyositis in a Patient with Metastatic Melanoma","volume":"10","author":"Lin","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_140","first-page":"6430156","article-title":"A Case of New-Onset Dermatomyositis in the Second Trimester of Pregnancy: A Case Report and Review of the Literature","volume":"2016","author":"Akalin","year":"2016","journal-title":"Case Rep. Obstet. Gynecol."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.jaad.2004.05.024","article-title":"Amyopathic dermatomyositis presenting during pregnancy","volume":"51","author":"Morihara","year":"2004","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1046\/j.1365-2133.1999.03165.x","article-title":"A case of dermatomyositis that developed after delivery: The involvement of pregnancy in the induction of dermatomyositis","volume":"141","author":"Kanoh","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"ref_143","first-page":"17","article-title":"Autoimmune Inflammatory Myopathy in Pregnancy","volume":"10","author":"Chopra","year":"2008","journal-title":"Medscape J. Med."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s00393-006-0059-y","article-title":"Seltene autoimmune rheumatische erkrankungen in der schwangerschaft. Systemische sklerose, polymyositis\/dermatomyositis und vaskulitiden","volume":"65","author":"Doria","year":"2006","journal-title":"Z. Rheumatol."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1093\/rheumatology\/keg318","article-title":"Pregnancy outcome in adult-onset idiopathic inflammatory myopathy","volume":"42","author":"Silva","year":"2003","journal-title":"Rheumatology"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1067\/mjd.2000.102648","article-title":"An unusual presentation of dermatomyositis: The type Wong variant revisited","volume":"43","author":"Lupton","year":"2000","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/cup.12733","article-title":"Wong-type dermatomyositis: A mimic of many dermatoses","volume":"43","author":"Mutasim","year":"2016","journal-title":"J. Cutan. Pathol."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"325","DOI":"10.5826\/dpc.0904a22","article-title":"Wong-Type Dermatomyositis: An Extremely Rare Disease in Childhood","volume":"9","author":"Diplomatico","year":"2019","journal-title":"Dermatol. Pract. Concept."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/j.1365-2133.1969.tb16031.x","article-title":"Dermatomyositis: A clinical investigation of twenty-three cases in Hong Kong","volume":"81","author":"Wong","year":"1969","journal-title":"Br. J. Dermatol."},{"key":"ref_150","first-page":"288","article-title":"Dermatomyositis","volume":"46","author":"Simpson","year":"1953","journal-title":"Proc. R. Soc. Med."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1111\/ajd.13393","article-title":"A case of Wong-type dermatomyositis treated with rituximab and IVIG","volume":"62","author":"Argobi","year":"2021","journal-title":"Australas. J. Dermatol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.jdcr.2018.08.006","article-title":"Wong-type dermatomyositis during anti\u2013PD-1 therapy","volume":"4","author":"Yu","year":"2018","journal-title":"JAAD Case Rep."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/ddg.14068","article-title":"Wong-type dermatomyositis with pulmonary involvement in a teenager: Case report","volume":"18","author":"Poehls","year":"2020","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1525-1470.2007.00364.x","article-title":"Dermatomyositis with a pityriasis rubra pilaris-like eruption: An uncommon cutaneous manifestation in dermatomyositis","volume":"24","author":"Polat","year":"2007","journal-title":"Pediatr. Dermatol."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/ajd.14456","article-title":"Case Report of Dermatomyositis With Features of the Wong Variant Developing Post-Trastuzumab Therapy for Breast Cancer","volume":"66","author":"LaMonica","year":"2025","journal-title":"Australas. J. Dermatol."},{"key":"ref_156","doi-asserted-by":"crossref","unstructured":"Russo, R., Gasparini, G., Cozzani, E., Gravina, B., and Parodi, A. (2022). Paraneoplastic Wong-Type Dermatomyositis Associated with Gynecological Malignancy. Medicina, 58.","DOI":"10.3390\/medicina58040484"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"547","DOI":"10.4103\/idoj.idoj_386_22","article-title":"Wong-Type Dermatomyositis: A Report of Two Cases","volume":"14","author":"Ashraf","year":"2023","journal-title":"Indian Dermatol. Online J."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000371573","article-title":"Wong-Type Dermatomyositis Showing Porokeratosis-Like Changes (Columnar Dyskeratosis): A Case Report and Review of the Literature","volume":"2","author":"Umanoff","year":"2015","journal-title":"Dermatopathology"},{"key":"ref_159","first-page":"115","article-title":"Wong-type dermatomyositis","volume":"153","author":"Didona","year":"2018","journal-title":"G. Ital. Dermatol. Venereol."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"385","DOI":"10.4103\/ijd.ijd_827_22","article-title":"Anti-Mi-2 Antibodies Wong Type Dermatomyositis with Columnar Dyskeratosis","volume":"70","author":"Bularca","year":"2025","journal-title":"Indian J. Dermatol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"68","DOI":"10.7326\/0003-4819-84-1-68","article-title":"Dermatomyositis and malignancy. A review of the literature","volume":"84","author":"Barnes","year":"1976","journal-title":"Ann. Intern. Med."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1001\/jamaneurol.2017.0934","article-title":"Skeletal Muscle Involvement in Antisynthetase Syndrome","volume":"74","author":"Noguchi","year":"2017","journal-title":"JAMA Neurol."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/CPM.0000000000000171","article-title":"The Diagnosis and Treatment of Antisynthetase Syndrome","volume":"23","author":"Witt","year":"2016","journal-title":"Clin. Pulm. Med."},{"key":"ref_164","doi-asserted-by":"crossref","unstructured":"Wells, M., Alawi, S., Thin, K.Y.M., Gunawardena, H., Brown, A.R., Edey, A., Pauling, J.D., Barratt, S.L., and Adamali, H.I. (2022). A multidisciplinary approach to the diagnosis of antisynthetase syndrome. Front. Med., 9.","DOI":"10.3389\/fmed.2022.959653"},{"key":"ref_165","first-page":"663","article-title":"Antibody to Jo-1 in polymyositis\/dermatomyositis: Association with interstitial pulmonary disease","volume":"11","author":"Hochberg","year":"1984","journal-title":"J. Rheumatol."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1378\/chest.10-0180","article-title":"Interstitial lung disease associated with the idiopathic inflammatory myopathies: What progress has been made in the past 35 years?","volume":"138","author":"Connors","year":"2010","journal-title":"Chest"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"309","DOI":"10.55563\/clinexprheumatol\/8xj0b9","article-title":"Defining anti-synthetase syndrome: A systematic literature review","volume":"40","author":"Zanframundo","year":"2022","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_168","unstructured":"(2021, February 01). Orphanet: Antisynthetase Syndrome. Available online: https:\/\/www.orpha.net\/en\/disease\/detail\/81."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1136\/annrheumdis-2017-211868","article-title":"The EuroMyositis registry: An international collaborative tool to facilitate myositis research","volume":"77","author":"Lilleker","year":"2018","journal-title":"Ann. Rheum. Dis."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0248-8663(01)00552-5","article-title":"The antisynthetase syndrome: A subgroup of inflammatory myopathies not to be unrecognized","volume":"23","author":"Legout","year":"2002","journal-title":"Rev. Med. Interne"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/MD.0000000000001144","article-title":"Clinical Spectrum Time Course in Anti Jo-1 Positive Antisynthetase Syndrome: Results From an International Retrospective Multicenter Study","volume":"94","author":"Cavagna","year":"2015","journal-title":"Medicine"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3899\/jrheum.180355","article-title":"Nailfold Capillaroscopy Characteristics of Antisynthetase Syndrome and Possible Clinical Associations: Results of a Multicenter International Study","volume":"46","author":"Sebastiani","year":"2019","journal-title":"J. Rheumatol."},{"key":"ref_173","first-page":"8","article-title":"Clinical profile and treatment outcomes in antisynthetase syndrome: A tertiary centre experience","volume":"5","author":"Sreevilasan","year":"2021","journal-title":"Rheumatol. Adv. Pract."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1136\/annrheumdis-2012-201800","article-title":"Patients with non-Jo-1 anti-tRNA-synthetase autoantibodies have worse survival than Jo-1 positive patients","volume":"73","author":"Aggarwal","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Cavagna, L., Trallero-Aragu\u00e1s, E., Meloni, F., Cavazzana, I., Rojas-Serrano, J., Feist, E., Zanframuno, G., Morandi, V., Meyer, A., and Pereira da Silva, J.A. (2019). Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course. J. Clin. Med., 8.","DOI":"10.3390\/jcm8112013"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00408-014-9665-7","article-title":"Comparison of pulmonary involvement between patients expressing anti-PL-7 and anti-Jo-1 antibodies","volume":"193","author":"Tomonaga","year":"2015","journal-title":"Lung"},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.semarthrit.2011.09.008","article-title":"Short-term and long-term outcome of anti-Jo1-positive patients with anti-Ro52 antibody","volume":"41","author":"Marie","year":"2012","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.autrev.2019.05.002","article-title":"Anti-OJ autoantibodies: Rare or underdetected?","volume":"18","author":"Vulsteke","year":"2019","journal-title":"Autoimmun. Rev."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"105920","DOI":"10.1016\/j.rmed.2020.105920","article-title":"Clinical characteristics of patients with anti-EJ antisynthetase syndrome associated interstitial lung disease and literature review","volume":"165","author":"Liu","year":"2020","journal-title":"Respir. Med."},{"key":"ref_180","doi-asserted-by":"crossref","unstructured":"Sohara, E., Saraya, T., Sato, S., Tsujimoto, N., Watanabe, T., Takata, S., Tanaka, Y., Ishii, H., Takizawa, H., and Goto, H. (2014). Mechanic\u2019s hands revisited: Is this sign still useful for diagnosis in patients with lung involvement of collagen vascular diseases?. BMC Res. Notes, 7.","DOI":"10.1186\/1756-0500-7-303"},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.annder.2018.11.010","article-title":"Mechanics hands in patients with antisynthetase syndrome: 25 cases","volume":"146","author":"Gusdorf","year":"2019","journal-title":"Ann. Dermatol. Venereol."},{"key":"ref_182","doi-asserted-by":"crossref","unstructured":"Patel, P., Marinock, J.M., Ajmeri, A., and Brent, L.H. (2024). A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25084453"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1365-2133.2006.07593.x","article-title":"\u201cMechanic\u2019s hands\u201d: A misleading cutaneous sign of the antisynthetase syndrome","volume":"156","author":"Bachmeyer","year":"2007","journal-title":"Br. J. Dermatol."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.autrev.2014.03.004","article-title":"The clinical phenotype associated with myositis-specific and associated autoantibodies: A meta-analysis revisiting the so-called antisynthetase syndrome","volume":"13","author":"Lega","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s12016-016-8528-9","article-title":"Serum Jo-1 Autoantibody and Isolated Arthritis in the Antisynthetase Syndrome: Review of the Literature and Report of the Experience of AENEAS Collaborative Group","volume":"52","author":"Cavagna","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"E1365","DOI":"10.1503\/cmaj.170819","article-title":"Mechanic\u2019s hands and hiker\u2019s feet in antisynthetase syndrome","volume":"189","author":"Wernham","year":"2017","journal-title":"Can. Med. Assoc. J."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"202","DOI":"10.31138\/mjr.301023.mfh","article-title":"Mechanic\u2019s Feet (Hiker\u2019s Feet) in Anti-Synthetase Syndrome","volume":"35","author":"Kumar","year":"2023","journal-title":"Mediterr. J. Rheumatol."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1007\/s10067-017-3598-5","article-title":"\u201cHiker\u2019s feet\u201d: A novel cutaneous finding in the inflammatory myopathies","volume":"36","author":"Cox","year":"2017","journal-title":"Clin. Rheumatol."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/RHU.0b013e31823b1878","article-title":"Antisynthetase syndrome and malignancy: Our experience","volume":"17","author":"Grau","year":"2011","journal-title":"J. Clin. Rheumatol."},{"key":"ref_190","first-page":"169","article-title":"Cancer-associated myositis in the presence of anti-Jo1 autoantibodies and the antisynthetase syndrome","volume":"35","author":"Legault","year":"2008","journal-title":"J. Rheumatol."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/RHU.0b013e3181b0e910","article-title":"Clinical Characteristics of Patients with Anti-Jo-1 Antibodies: A Single Center Experience","volume":"15","author":"Mileti","year":"2009","journal-title":"J. Clin. Rheumatol."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.autrev.2012.06.006","article-title":"Hierarchical cluster and survival analyses of antisynthetase syndrome: Phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity","volume":"12","author":"Hervier","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/ccr3.6488","article-title":"Flagellate dermatitis: An atypical skin finding in adult-onset Still\u2019s disease","volume":"10","author":"Toujani","year":"2022","journal-title":"Clin. Case Rep."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.medcli.2022.06.005","article-title":"Flagellate dermatitis","volume":"159","year":"2022","journal-title":"Med. Clin."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1093\/rheumatology\/keaa676","article-title":"Flagellate erythema as sign of paraneoplastic dermatomyositis","volume":"60","author":"Maione","year":"2021","journal-title":"Rheumatology"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/j.1365-2230.1996.tb00151.x","article-title":"Dermatomyositis and flagellate erythema","volume":"21","author":"Jara","year":"1996","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000246691","article-title":"\u201cFlagellate\u201d erythema in dermatomyositis","volume":"190","author":"Watanabe","year":"1995","journal-title":"Dermatology"},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"134","DOI":"10.25259\/IJDVL_553_2024","article-title":"Flagellate erythema: A rare presentation of idiopathic dermatomyositis","volume":"91","author":"Choi","year":"2025","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/ijd.17384","article-title":"A case of amyopathic dermatomyositis with flagellate dermatitis","volume":"64","author":"Shi","year":"2025","journal-title":"Int. J. Dermatol."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s13256-020-02514-6","article-title":"Degos disease: A case report and review of the literature","volume":"14","author":"Tummidi","year":"2020","journal-title":"J. Med. Case Rep."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s13023-021-01819-z","article-title":"Clinical and laboratory prognosticators of atrophic papulosis (Degos disease): A systematic review","volume":"16","author":"Lu","year":"2021","journal-title":"Orphanet J. Rare Dis."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1046\/j.1365-4362.2000.00828.x","article-title":"Degos\u2019 disease","volume":"39","author":"Ermete","year":"2000","journal-title":"Int. J. Dermatol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1007\/s00296-019-04495-2","article-title":"Juvenile dermatomyositis resembling late-stage Degos disease with gastrointestinal perforations successfully treated with combination of cyclophosphamide and rituximab: Case-based review","volume":"40","author":"Day","year":"2020","journal-title":"Rheumatol. Int."},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/acr2.11570","article-title":"Clinical Images: Degos-like lesions in association with NXP-2 dermatomyositis","volume":"5","author":"Alhassan","year":"2023","journal-title":"ACR Open Rheumatol."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/j.1600-0560.2008.01171.x","article-title":"Fulminant and accelerated presentation of dermatomyositis in two previously healthy young adult males: A potential role for endotheliotropic viral infection","volume":"36","author":"Magro","year":"2009","journal-title":"J. Cutan. Pathol."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"e001934","DOI":"10.1136\/rmdopen-2021-001934","article-title":"SIGLEC1 enables straightforward assessment of type I interferon activity in idiopathic inflammatory myopathies","volume":"8","author":"Graf","year":"2022","journal-title":"RMD Open"},{"key":"ref_207","doi-asserted-by":"crossref","unstructured":"Raupov, R., Suspitsin, E., Preobrazhenskaya, E.V., and Kostik, M. (2024). Interferon type I signature associated with skin disease in juvenile dermatomyositis. Front. Med., 11.","DOI":"10.3389\/fmed.2024.1214920"},{"key":"ref_208","doi-asserted-by":"crossref","unstructured":"Zhang, X., Ma, Y., Liu, K., Chen, L., Ding, L., and Ma, W. (2023). Risk prediction for dermatomyositis-associated hepatocellular carcinoma. BMC Bioinform., 1.","DOI":"10.1186\/s12859-023-05353-6"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/8\/2874\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T04:20:12Z","timestamp":1775967612000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/8\/2874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,10]]},"references-count":208,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["jcm15082874"],"URL":"https:\/\/doi.org\/10.3390\/jcm15082874","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,10]]}}}