{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:07:13Z","timestamp":1775815633713,"version":"3.50.1"},"reference-count":27,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Atrial fibrillation (AF) is a significant and prevalent cardiovascular complication in end-stage renal disease (ESRD) patients, yet its specific predictors within this population are not well understood. This study aimed to identify the predictors of new-onset AF in ESRD patients undergoing dialysis. Methods: We conducted a retrospective multicenter cohort study within the Northwell Health System, analyzing data from 5326 ESRD patients on dialysis between 2017 and 2019. The mean age was 64.2 \u00b1 13.1 years, with 48.3% females. Multivariable-adjusted logistic regression was used to identify predictors of new-onset AF, the primary outcome. Adjusted odds ratios (ORs) were calculated for potential risk factors. Results: Of the 5326 patients, 1564 (29.4%) developed new-onset AF. Significant predictors included increasing age (OR 1.038 per year, 95% CI 1.032\u20131.044, p &lt; 0.0001), obesity (BMI &gt; 30 vs. BMI 20\u201325: OR 1.208, 95% CI 1.026\u20131.422, p = 0.023), and coronary artery disease (OR 1.678, 95% CI 1.466\u20131.920, p &lt; 0.0001). African American patients had lower odds of developing AF compared to White patients (OR 0.578, 95% CI 0.494\u20130.676, p &lt; 0.0001). Hypertension, sex, diabetes, and tobacco use were not significantly associated with AF risk. Conclusions: Age, obesity, and coronary artery disease are significant predictors of new-onset AF in ESRD patients on dialysis. Notable racial disparities exist, with African American patients having a lower risk. These findings may inform targeted prevention strategies and guide future research into the mechanisms underlying AF in ESRD patients.<\/jats:p>","DOI":"10.3390\/jcm15082879","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T09:08:12Z","timestamp":1775812092000},"page":"2879","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Predictors of New-Onset Atrial Fibrillation in End-Stage Renal Disease Patients: A Multi-Center Retrospective Observational Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3399-760X","authenticated-orcid":false,"given":"Ahmed A.","family":"Zayed","sequence":"first","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad Bahij","family":"Moumneh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8086-2928","authenticated-orcid":false,"given":"Bahy","family":"Abofrekha","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Itani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7010-9433","authenticated-orcid":false,"given":"Omar","family":"Khayat","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelrahman","family":"Abouelnas","sequence":"additional","affiliation":[{"name":"Department of Medicine, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin M.","family":"Amor","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Northwell Health Staten Island University Hospital, 475 Seaview Ave., New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1016\/j.jacc.2019.08.1031","article-title":"Anticoagulation in Concomitant Chronic Kidney Disease and Atrial Fibrillation: JACC Review Topic of the Week","volume":"74","author":"Kumar","year":"2019","journal-title":"J. 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