{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:39:31Z","timestamp":1787236771476,"version":"build-2736575974"},"reference-count":25,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective: To investigate the association between pelvic incidence (PI) and fixation failure following single-level transforaminal lumbar interbody fusion (TLIF) for low-grade spondylolisthesis and to identify risk factors for pedicle screw loosening. Methods: This retrospective study included 80 patients who underwent single-level TLIF and were divided into a high PI group (n = 40) and a normal\/low PI group (n = 40). Radiographic parameters including PI, lumbar lordosis (LL), pelvic tilt (PT), sacra l slope (SS), listhesis magnitude, and PI-LL mismatch were evaluated pre- and postoperatively. Screw loosening and fusion status were assessed at 6, 12, and 24 months. Multivariate logistic regression analysis was performed to identify independent risk factors for screw loosening. Results: The high PI group demonstrated significantly higher screw loosening rates than the normal\/low PI group at all follow-up time points, with a rate of 57.5% versus 28.2% at 24 months (p = 0.012). Fusion rates were comparable between groups. Multivariate analysis identified high PI and residual listhesis were independent risk factors for screw loosening (Odds ratio 1.05 and 1.35). PI-LL mismatch &gt; 10\u00b0 showed higher odds but were not statistically significant. Conclusions: High PI is associated with an increased risk of pedicle screw loosening after single-level TLIF. Careful preoperative assessment and postoperative monitoring may help reduce fixation-related complications.<\/jats:p>","DOI":"10.3390\/jcm15093199","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T13:44:33Z","timestamp":1776865473000},"page":"3199","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of High Pelvic Incidence on Fixation Failure in Single-Level Transforaminal Lumbar Interbody Fusion for Low-Grade Spondylolisthesis: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6394-1439","authenticated-orcid":false,"given":"Koopong","family":"Siribumrungwong","sequence":"first","affiliation":[{"name":"Chulabhorn International College of Medicine, Thammasat University, Pathum Thani 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sansern","family":"Satthanan","sequence":"additional","affiliation":[{"name":"Department of Orthopedic, Rajthanee Nongkhae Hospital, Saraburi 18230, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2684-2748","authenticated-orcid":false,"given":"Bunyaporn","family":"Wuttiworawanit","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Punnawit","family":"Pinitchanon","sequence":"additional","affiliation":[{"name":"Department of Orthopedic, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thongchai","family":"Suntharapa","sequence":"additional","affiliation":[{"name":"Department of Orthopedic, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"ref_1","first-page":"2","article-title":"Lumbar interbody fusion: Techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF\/ATP, LLIF and ALIF","volume":"1","author":"Mobbs","year":"2015","journal-title":"J. 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