{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T23:36:58Z","timestamp":1785022618741,"version":"3.55.0"},"reference-count":58,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Congenital cytomegalovirus (CMV) infection is the most common congenital infection worldwide and a leading cause of neurodevelopment impairment. Prenatal imaging plays a central role in diagnosis and prognostic assessment. Methods: We conducted a systematic review of studies evaluating the role of ultrasound, including dedicated fetal neurosonography and magnetic resonance imaging (MRI) in the prenatal detection and assessment of CMV infection. PubMed, Web of Science, and Scopus were searched for relevant studies, and data were synthesized focusing on detected abnormalities and the incremental diagnostic value of MRI. Results: Fifty-nine studies were included. Dedicated neurosonography (NSG) was the primary modality for detecting CMV-related fetal brain abnormalities, particularly ventriculomegaly and cortical malformations. Fetal MRI provided additional diagnostic information, mainly through improved visualization of the brain parenchyma, allowing better detection of white matter abnormalities, migrational disorders and posterior fossa involvement, especially when performed later in gestation. Conclusions: Dedicated neurosonography remains the cornerstone for the evaluation of suspected congenital fetal CMV infection. Fetal MRI represents a complementary tool that can confirm, refine or extend ultrasound findings and may improve prognostic assessment when additional or subtle brain abnormalities are suspected.<\/jats:p>","DOI":"10.3390\/jcm15103645","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:17:42Z","timestamp":1778519862000},"page":"3645","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Role of Ultrasound and Fetal MRI in the Prenatal Assessment of Congenital Cytomegalovirus Infection: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"given":"Katarzyna","family":"Stefanska","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Medical University of Gdansk, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8234-6691","authenticated-orcid":false,"given":"Krzysztof","family":"Berbeka","sequence":"additional","affiliation":[{"name":"Ist Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, 01-813 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Madej","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Medical University of Gdansk, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0078-8801","authenticated-orcid":false,"given":"Piotr","family":"Witkowski","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Medical University of Gdansk, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Rybak-Krzyszkowska","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Perinatology, University Hospital, 31-501 Krakow, Poland"},{"name":"Hi-Gen Centrum Medyczne, 31-322 Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6496-3282","authenticated-orcid":false,"given":"Sambor","family":"Sawicki","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Medical University of Gdansk, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Illa","sequence":"additional","affiliation":[{"name":"BCNatal, Fetal Medicine Research Center (Hospital Clinic and Hospital Sant Joan de D\u00e9u), Universitat de Barcelona, 08007 Barcelona, Spain"},{"name":"Institut de Recerca Sant Joan de D\u00e9u (IRSJD), Fundaci\u00f3 Sant Joan de D\u00e9u, 08014 Barcelona, Spain"},{"name":"Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID, RD24\/0013\/0004), Instituto de Salud Carlos III, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1159\/000321346","article-title":"Imaging of Fetal Cytomegalovirus Infection","volume":"29","author":"Malinger","year":"2011","journal-title":"Fetal Diagn. Ther."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.ebiom.2015.08.003","article-title":"Prevention of Primary Cytomegalovirus Infection in Pregnancy","volume":"2","author":"Revello","year":"2015","journal-title":"EBioMedicine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ejogrb.2020.12.006","article-title":"Cytomegalovirus infection in pregnancy\u2014An update","volume":"258","author":"Navti","year":"2021","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Walker, S.P., Palma-Dias, R., Wood, E.M., Shekleton, P., and Giles, M.L. (2013). Cytomegalovirus in pregnancy: To screen or not to screen. BMC Pregnancy Childbirth, 13.","DOI":"10.1186\/1471-2393-13-96"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/GCO.0000000000000486","article-title":"Antenatal treatment options for primary cytomegalovirus infections","volume":"30","author":"Kagan","year":"2018","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1002\/jmri.29507","article-title":"Brain Metabolite Differences in Fetuses with Cytomegalovirus Infection: A Magnetic Resonance Spectroscopy Study","volume":"61","author":"Sadan","year":"2025","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.jogc.2021.05.015","article-title":"Guideline No. 420: Cytomegalovirus Infection in Pregnancy","volume":"43","author":"Boucoiran","year":"2021","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_8","first-page":"e1","article-title":"Congenital Cytomegalovirus Infection: Update on Treatment: Scientific Impact Paper No. 56","volume":"125","author":"Khalil","year":"2018","journal-title":"BJOG Int. J. Obstet. Gynaecol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Rybak-Krzyszkowska, M., G\u00f3recka, J., Huras, H., Massalska-Wolska, M., Sta\u015bkiewicz, M., Gach, A., Kondracka, A., Staniczek, J., G\u00f3rczewski, W., and Borowski, D. (2023). Cytomegalovirus Infection in Pregnancy Prevention and Treatment Options: A Systematic Review and Meta-Analysis. Viruses, 15.","DOI":"10.3390\/v15112142"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/uog.21991","article-title":"ISUOG Practice Guidelines: Role of ultrasound in congenital infection","volume":"56","author":"Khalil","year":"2020","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1053\/j.sult.2015.04.001","article-title":"Fetal Brain Magnetic Resonance Imaging Findings In Congenital Cytomegalovirus Infection with Postnatal Imaging Correlation","volume":"36","author":"Averill","year":"2015","journal-title":"Semin. Ultrasound CT MRI"},{"key":"ref_12","first-page":"1","article-title":"Cytomegalovirus infection in pregnancy: Review of the literature","volume":"5","author":"Bonalumi","year":"2011","journal-title":"J. Prenat. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/pd.5591","article-title":"The MRI spectrum of congenital cytomegalovirus infection","volume":"40","author":"Diogo","year":"2020","journal-title":"Prenat. Diagn."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"8001","DOI":"10.1007\/s00330-021-07776-2","article-title":"Brain MRI findings in newborns with congenital cytomegalovirus infection: Results from a large cohort study","volume":"31","author":"Keymeulen","year":"2021","journal-title":"Eur. Radiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/pd.5888","article-title":"A unique brain germinal matrix involvement in cytomegalovirus infected fetuses: A retrospective neurosonographic analysis with outcome correlation","volume":"41","author":"Birnbaum","year":"2021","journal-title":"Prenat. Diagn."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e1938","DOI":"10.1002\/rmv.1938","article-title":"Hearing and neurodevelopmental outcomes for children with asymptomatic congenital cytomegalovirus infection: A systematic review","volume":"27","author":"Bartlett","year":"2017","journal-title":"Rev. Med. Virol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1159\/000535917","article-title":"Clinical Practice Guidelines and Recommendations by the World Association of Perinatal Medicine and Perinatal Medicine Foundation: Reporting Suspected Findings from Fetal Central Nervous System Examination","volume":"51","author":"Sen","year":"2024","journal-title":"Fetal Diagn. Ther."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1515\/jpm-2021-0183","article-title":"WAPM-World Association of Perinatal Medicine Practice Guidelines: Fetal central nervous system examination","volume":"49","author":"Sen","year":"2021","journal-title":"J. Perinat. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/uog.22145","article-title":"ISUOG Practice Guidelines (updated): Sonographic examination of the fetal central nervous system. Part 1: Performance of screening examination and indications for targeted neurosonography","volume":"56","author":"Malinger","year":"2020","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/1471-0528.15935","article-title":"Refining the prognosis of fetuses infected with Cytomegalovirus in the first trimester of pregnancy by serial prenatal assessment: A single-centre retrospective study","volume":"127","author":"Millischer","year":"2020","journal-title":"BJOG Int. J. Obstet. Gynaecol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/uog.24856","article-title":"Anatomical and diffusion-weighted imaging of brain abnormalities in third-trimester fetuses with cytomegalovirus infection","volume":"60","author":"Aertsen","year":"2022","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"342.e1","DOI":"10.1016\/j.ajog.2016.03.052","article-title":"Feasibility of predicting the outcome of fetal infection with cytomegalovirus at the time of prenatal diagnosis","volume":"215","author":"Stirnemann","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejogrb.2024.01.037","article-title":"Counseling in fetal medicine: Congenital cytomegalovirus infection","volume":"295","author":"Rizzo","year":"2024","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.1111\/1471-0528.17966","article-title":"Congenital Cytomegalovirus Infection: Update on Screening, Diagnosis and Treatment: Scientific Impact Paper No. 56","volume":"132","author":"Khalil","year":"2025","journal-title":"BJOG Int. J. Obstet. Gynaecol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/pd.2694","article-title":"Does normal fetal brain ultrasound predict normal neurodevelopmental outcome in congenital cytomegalovirus infection?","volume":"31","author":"Farkas","year":"2011","journal-title":"Prenat. Diagn."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/uog.23143","article-title":"Outcome of fetuses with congenital cytomegalovirus infection and normal ultrasound at diagnosis: Systematic review and meta-analysis","volume":"57","author":"Buca","year":"2021","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1055\/s-2004-815833","article-title":"The Spectrum of Cranial Ultrasound and Magnetic Resonance Imaging Abnormalities in Congenital Cytomegalovirus Infection","volume":"35","author":"Gunardi","year":"2004","journal-title":"Neuropediatrics"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/uog.7657","article-title":"Value of prenatal ultrasound and magnetic resonance imaging in assessment of congenital primary cytomegalovirus infection","volume":"36","author":"Lipitz","year":"2010","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Rybak-Krzyszkowska, M., G\u00f3recka, J., Huras, H., Sta\u015bkiewicz, M., Kondracka, A., Staniczek, J., G\u00f3rczewski, W., Borowski, D., Grzesiak, M., and Krzeszowski, W. (2023). Ultrasonographic Signs of Cytomegalovirus Infection in the Fetus\u2014A Systematic Review of the Literature. Diagnostics, 13.","DOI":"10.3390\/diagnostics13142397"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1515\/jpm-2019-0331","article-title":"Prenatal findings, neonatal symptoms and neurodevelopmental outcome of congenital cytomegalovirus infection in a university hospital in Montreal, Quebec","volume":"48","author":"Minsart","year":"2020","journal-title":"J. Perinat. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000541794","article-title":"Callosal Injuries in Cytomegalovirus Fetopathy: A Neurosonographic Study","volume":"52","author":"Malinger","year":"2024","journal-title":"Fetal Diagn. Ther."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.bpobgyn.2016.10.005","article-title":"Fetal cytomegalovirus infection","volume":"38","author":"Ville","year":"2017","journal-title":"Best. Pract. Res. Clin. Obstet. Gynaecol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"E419","DOI":"10.1111\/j.1469-0691.2012.03983.x","article-title":"Congenital cytomegalovirus infection: Patterns of fetal brain damage","volume":"18","author":"Gabrielli","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.ajog.2020.02.018","article-title":"Cytomegalovirus infection during pregnancy: State of the science","volume":"223","author":"Foulon","year":"2020","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/cid\/ciy1128","article-title":"Sequelae of Congenital Cytomegalovirus Following Maternal Primary Infections Are Limited to Those Acquired in the First Trimester of Pregnancy","volume":"69","author":"Magny","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1007\/s00330-015-4187-0","article-title":"Congenital cytomegalovirus infection: Contribution and best timing of prenatal MR imaging","volume":"26","author":"Cannie","year":"2016","journal-title":"Eur. Radiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/uog.26129","article-title":"ISUOG Practice Guidelines (updated): Performance of fetal magnetic resonance imaging","volume":"61","author":"Prayer","year":"2023","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1080\/14767058.2019.1620725","article-title":"A new MRI severity score to predict long-term adverse neurologic outcomes in children with congenital Cytomegalovirus infection","volume":"34","author":"Lucignani","year":"2021","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"The ENSO Working Group (2020). Role of prenatal magnetic resonance imaging in fetuses with isolated mild or moderate ventriculomegaly in the era of neurosonography: International multicenter study. Ultrasound Obstet. Gynecol., 56, 340\u2013347.","DOI":"10.1002\/uog.21974"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/uog.20197","article-title":"Role of magnetic resonance imaging in fetuses with mild or moderate ventriculomegaly in the era of fetal neurosonography: Systematic review and meta-analysis","volume":"54","author":"Sileo","year":"2019","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"The ENSO Working Group (2021). Role of prenatal magnetic resonance imaging in fetuses with isolated anomalies of corpus callosum: Multinational study. Ultrasound Obstet. Gynecol., 58, 26\u201333.","DOI":"10.1002\/uog.23612"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/uog.26054","article-title":"Role of fetal magnetic resonance imaging in fetuses with congenital cytomegalovirus infection: Multicenter study","volume":"61","author":"Rizzo","year":"2023","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1148\/radiol.10090749","article-title":"Early Cerebral Lesions in Cytomegalovirus Infection: Prenatal MR Imaging","volume":"255","author":"Doneda","year":"2010","journal-title":"Radiology"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1002\/uog.23616","article-title":"ISUOG Practice Guidelines (updated): Sonographic examination of the fetal central nervous system. Part 2: Performance of targeted neurosonography","volume":"57","author":"Paladini","year":"2021","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1002\/pd.5180","article-title":"The use of fetal neurosonography and brain MRI in cases of cytomegalovirus infection during pregnancy: A retrospective analysis with outcome correlation","volume":"37","author":"Birnbaum","year":"2017","journal-title":"Prenat. Diagn."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1111\/1754-9485.13083","article-title":"Prenatal cranial MR findings in fetuses with suspected CMV infection: Correlation with postnatal outcome and differential diagnostic considerations","volume":"64","author":"Goergen","year":"2020","journal-title":"J. Med. Imaging Radiat. Oncol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jinf.2020.02.012","article-title":"Antenatal imaging and clinical outcome in congenital CMV infection: A field-wide systematic review and meta-analysis","volume":"80","author":"Kyriakopoulou","year":"2020","journal-title":"J. Infect."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/pd.5638","article-title":"Outcome of fetal echogenic bowel: A systematic review and meta-analysis","volume":"41","author":"Buca","year":"2021","journal-title":"Prenat. Diagn."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"380.e1","DOI":"10.1016\/j.ajog.2007.09.052","article-title":"Ultrasound prediction of symptomatic congenital cytomegalovirus infection","volume":"198","author":"Guerra","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"19706","DOI":"10.1038\/s41598-020-76772-1","article-title":"Clinical and ultrasound features associated with congenital cytomegalovirus infection as potential predictors for targeted newborn screening in high-risk pregnancies","volume":"10","author":"Imafuku","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.jpeds.2013.12.007","article-title":"Spectrum of Disease and Outcome in Children with Symptomatic Congenital Cytomegalovirus Infection","volume":"164","author":"Dreher","year":"2014","journal-title":"J. Pediatr."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/uog.21946","article-title":"Revisiting short- and long-term outcome after fetal first-trimester primary cytomegalovirus infection in relation to prenatal imaging findings","volume":"56","author":"Lipitz","year":"2020","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_54","first-page":"28","article-title":"Fetal cytomegalovirus infection of the brain: The spectrum of sonographic findings","volume":"24","author":"Malinger","year":"2003","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"5928398","DOI":"10.1155\/2017\/5928398","article-title":"Sequence and Timing of Intracranial Changes in Cytomegalovirus in Pregnancy: A Case Report and Literature Review","volume":"2017","author":"Arulkumaran","year":"2017","journal-title":"Case Rep. Obstet. Gynecol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"599.e1","DOI":"10.1016\/j.ajog.2009.12.021","article-title":"Fetal cerebral periventricular halo at midgestation: An ultrasound finding suggestive of fetal cytomegalovirus infection","volume":"202","author":"Simonazzi","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/uog.26173","article-title":"Halo sign in fetal cytomegalovirus infection: Cerebral imaging abnormalities and postmortem histopathology in 35 infected fetuses","volume":"61","author":"Castillo","year":"2023","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ejogrb.2021.10.014","article-title":"Role of prenatal magnetic resonance imaging in fetuses with isolated severe ventriculomegaly at neurosonography: A multicenter study","volume":"267","author":"Khalil","year":"2021","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/10\/3645\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:39:58Z","timestamp":1778521198000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/10\/3645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,9]]},"references-count":58,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["jcm15103645"],"URL":"https:\/\/doi.org\/10.3390\/jcm15103645","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,9]]}}}