{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:17:11Z","timestamp":1778779031125,"version":"3.51.4"},"reference-count":22,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Postpartum anemia frequently requires packed red blood cell (PRBC) transfusion; however, the contribution of intravenous iron to early hematologic recovery remains uncertain. This study evaluated hemoglobin dynamics following transfusion and the effect of adjunctive intravenous iron therapy. Methods: In this retrospective cohort study, 61 obstetric patients requiring PRBC transfusion were included. Hematologic parameters were assessed at admission, postoperatively, post-transfusion, and at day 7. Patients were stratified according to the administration of intravenous ferric carboxymaltose. Hemoglobin changes and reticulocyte response were analyzed, including a subgroup receiving two PRBC units. Results: Mean hemoglobin decreased from 9.36 \u00b1 1.16 g\/dL at admission to 6.33 \u00b1 1.05 g\/dL postoperatively, increased to 8.32 \u00b1 0.78 g\/dL after transfusion, and reached 8.75 \u00b1 0.97 g\/dL at day 7 (p &lt; 0.001). No significant differences between groups were observed before or immediately after transfusion. At day 7, hemoglobin was significantly higher in patients receiving intravenous iron compared with those without supplementation (9.63 \u00b1 1.03 vs. 8.03 \u00b1 0.36 g\/dL, p &lt; 0.001). The increase in hemoglobin from post-transfusion to day 7 was greater in the iron group (1.14 \u00b1 0.84 vs. \u22120.15 \u00b1 0.33 g\/dL, p &lt; 0.001), accompanied by a higher reticulocyte response (2.56 \u00b1 0.49% vs. 0.93 \u00b1 0.26%, p &lt; 0.001). Similar findings were observed in the two-unit subgroup. Conclusions: Adjunctive intravenous iron was associated with improved early hemoglobin recovery after transfusion without affecting immediate correction, supporting its clinical use in obstetric patients.<\/jats:p>","DOI":"10.3390\/jcm15103766","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:27:56Z","timestamp":1778776076000},"page":"3766","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Adjunctive Intravenous Iron Therapy on Hemoglobin Recovery in Obstetric Patients: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Mihaela","family":"Ichim","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, Elias University Emergency Hospital, 17 M\u0103r\u0103\u0219ti Blvd., 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Bot","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, Elias University Emergency Hospital, 17 M\u0103r\u0103\u0219ti Blvd., 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreea","family":"Borislavschi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, Elias University Emergency Hospital, 17 M\u0103r\u0103\u0219ti Blvd., 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Filipescu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania"},{"name":"Department of Obstetrics and Gynecology, Elias University Emergency Hospital, 17 M\u0103r\u0103\u0219ti Blvd., 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e627","DOI":"10.1016\/S2214-109X(22)00084-5","article-title":"National, regional, and global estimates of anaemia by severity in women and children for 2000\u201319: A pooled analysis of population-representative data","volume":"10","author":"Stevens","year":"2022","journal-title":"Lancet Glob. 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