{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:52:49Z","timestamp":1790200369110,"version":"4.1.0"},"reference-count":27,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: To systematically review the evidence on the association between early childhood caries (ECC) and oral health-related quality of life (OHRQoL) in preschool children, focusing on studies using the Early Childhood Oral Health Impact Scale (ECOHIS) or its validated language versions. Methods: This systematic review was conducted and reported in accordance with the PRISMA 2020 guidelines. Electronic searches identified primary observational studies published within the last 10 years. Eligible studies included preschool children, clinically assessed ECC\/caries, and OHRQoL measured with ECOHIS or a validated, adapted version. Data extraction covered study characteristics, caries assessment, OHRQoL measures, and main findings. Risk of bias was assessed using the Joanna Briggs Institute appraisal tools. Results: Twenty studies were included (19 cross-sectional and 1 cohort) with sample sizes ranging from 151 to 1783 participants. Across diverse populations and settings, ECC was consistently associated with poorer OHRQoL in preschool children and their families. Greater caries severity, untreated lesions, and advanced disease consequences were generally linked to higher ECOHIS scores. The most affected domains were pain, eating and drinking difficulties, sleep disturbance, irritability, and family distress. Conclusions: The available evidence consistently indicates that ECC is associated with poorer OHRQoL in preschool children and their families. From a clinical perspective, incorporating OHRQoL measures into pediatric dental assessment may improve recognition of disease burden beyond clinical indices alone.<\/jats:p>","DOI":"10.3390\/jcm15114314","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T14:38:42Z","timestamp":1780411122000},"page":"4314","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early Childhood Caries and Oral Health-Related Quality of Life in Preschool Children: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"given":"Paula","family":"Piekoszewska-Zi\u0119tek","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0248-6625","authenticated-orcid":false,"given":"Anna","family":"Turska-Szybka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Szczepanik","sequence":"additional","affiliation":[{"name":"Students\u2019 Research Group, Department of Pediatric Dentistry, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Olczak-Kowalczyk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"FDI World Dental Federation (2025). Early childhood caries. Int. Dent. J., 75, 5\u20136.","DOI":"10.1016\/j.identj.2024.12.005"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1186\/s12903-024-04605-y","article-title":"A systematic review and meta-analysis on early-childhood-caries global data","volume":"24","author":"Maklennan","year":"2024","journal-title":"BMC Oral Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s12903-025-05549-7","article-title":"Impact of the severity and extension of dental caries lesions on Turkish preschool children\u2019s oral health-related quality of life: A cross-sectional study","volume":"25","author":"Kurt","year":"2025","journal-title":"BMC Oral Health"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1111\/ipd.70000","article-title":"Sleep problems, early childhood caries, and oral health-related quality of life: An approach using structural equation modeling","volume":"35","author":"Bittencourt","year":"2025","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1730928","DOI":"10.3389\/froh.2026.1730928","article-title":"Is oral health-related quality of life of preschool children affected by the severity of early childhood caries?","volume":"7","author":"Alanzi","year":"2026","journal-title":"Front. Oral Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12903-025-07337-9","article-title":"Impact of dental caries on the quality of life of preschool children: A cross-sectional study within a birth cohort","volume":"26","author":"Raji","year":"2025","journal-title":"BMC Oral Health"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1186\/s12903-026-07655-6","article-title":"Oral health-related quality of life in a group of Egyptian preschool children with early childhood caries: A cross-sectional study","volume":"26","author":"Magdy","year":"2026","journal-title":"BMC Oral Health"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1477-7525-5-6","article-title":"Parental perceptions of children\u2019s oral health: The Early Childhood Oral Health Impact Scale (ECOHIS)","volume":"5","author":"Pahel","year":"2007","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e16035","DOI":"10.7717\/peerj.16035","article-title":"The Early Childhood Oral Health Impact Scale (ECOHIS): Psychometric properties and application on preschoolers","volume":"11","author":"Silva","year":"2023","journal-title":"PeerJ"},{"key":"ref_10","first-page":"222","article-title":"Dental caries rehabilitation and oral health-related quality of life in children, adolescents, and families: An updated systematic review","volume":"47","author":"Antunes","year":"2025","journal-title":"Pediatr. Dent."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e125","DOI":"10.1590\/1807-3107bor-2025.vol39.125","article-title":"Impact of clinical stage and location of dental caries lesions on oral health-related quality of life","volume":"39","author":"Abanto","year":"2025","journal-title":"Braz. Oral Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1186\/s12903-023-03274-7","article-title":"Does the severity of untreated dental caries of preschool children influence the oral health-related quality of life?","volume":"23","author":"Alanzi","year":"2023","journal-title":"BMC Oral Health"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1159\/000529908","article-title":"The impact of socio-environmental, individual, and biological factors on oral health-related quality of life among preschool children: A cohort study with 3-year follow-up","volume":"57","author":"Fernandes","year":"2023","journal-title":"Caries Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/ipd.12889","article-title":"Impact of early childhood caries severity on oral health-related quality of life among preschool children in Mexico: A cross-sectional study","volume":"32","author":"Lara","year":"2022","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12903-021-01396-4","article-title":"Impact of dental caries on oral health-related quality of life among preschool children: Perceptions of parents","volume":"21","author":"Pakkhesal","year":"2021","journal-title":"BMC Oral Health"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/idj.12526","article-title":"Oral health-related quality of life and caries experience of Hong Kong preschool children","volume":"70","author":"Duangthip","year":"2020","journal-title":"Int. Dent. J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e5283","DOI":"10.1590\/pboci.2020.065","article-title":"Impact of early childhood caries and maternal behaviors on oral health-related quality of life of children","volume":"20","author":"Pereira","year":"2020","journal-title":"Pesqui. Bras. Odontopediatria Clin. Integr."},{"key":"ref_19","first-page":"571","article-title":"Impact of dental caries on the quality of life of preschool children and families in Amman, Jordan","volume":"18","author":"Rajab","year":"2020","journal-title":"Oral Health Prev. Dent."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/idh.12414","article-title":"Factors influencing the oral health-related quality of life among children with severe early childhood caries in Hong Kong","volume":"17","author":"Lai","year":"2019","journal-title":"Int. J. Dent. Hyg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/ipd.12582","article-title":"Dental caries and oral health-related quality of life of 3-year-olds living in Lima, Peru","volume":"30","author":"Pesaressi","year":"2020","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Sharna, N., Ramakrishnan, M., Samuel, V., Ravikumar, D., Cheenglembi, K., and Anil, S. (2019). Association between early childhood caries and quality of life: Early Childhood Oral Health Impact Scale and pufa index. Dent. J., 7.","DOI":"10.3390\/dj7040095"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1590\/1413-81232018232.21022015","article-title":"Oral health outcomes: The association of clinical and socio-dental indicators to evaluate dental caries in preschool children","volume":"23","author":"Antunes","year":"2018","journal-title":"Cien. Saude Coletiva"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/cdoe.12279","article-title":"Oral health-related quality of life measures: Variation by socioeconomic status and caries experience","volume":"45","author":"Chaffee","year":"2017","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/00016357.2023.2287235","article-title":"Dental caries and oral health-related quality of life in preschoolers\u2014Introducing the Swedish version of the Early Childhood Oral Health Impact Scale (ECOHIS)","volume":"83","author":"Sabel","year":"2024","journal-title":"Acta Odontol. Scand."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/cdoe.12739","article-title":"Family functioning and preschool children\u2019s oral health-related quality of life","volume":"51","author":"Almutairi","year":"2023","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e064","DOI":"10.1590\/1807-3107bor-2022.vol36.0064","article-title":"Risk indicators of untreated dental caries incidence among preschoolers: A prospective longitudinal study","volume":"36","author":"Pordeus","year":"2022","journal-title":"Braz. Oral Res."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/11\/4314\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:05:03Z","timestamp":1780412703000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/11\/4314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":27,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["jcm15114314"],"URL":"https:\/\/doi.org\/10.3390\/jcm15114314","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]}}}