{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:56:48Z","timestamp":1785412608030,"version":"3.56.0"},"reference-count":23,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Recep Tayyip Erdogan University","award":["02025008018695"],"award-info":[{"award-number":["02025008018695"]}]},{"award":["02025008018695"],"award-info":[{"award-number":["02025008018695"]}],"id":[{"id":"https:\/\/ror.org\/0468j1635","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: To prospectively compare the outcomes of external dacryocystorhinostomy (EX-DCR), endonasal dacryocystorhinostomy (EN-DCR), and laser-assisted transcanalicular dacryocystorhinostomy (TL-DCR) in patients with nasolacrimal duct obstruction (NLDO) and to evaluate the relationship between surgical outcomes and patient quality of life (QoL). Methods: This prospective comparative study included patients presenting with epiphora who were diagnosed with NLDO and scheduled for surgical treatment. Patients underwent EX-DCR, EN-DCR, or TL-DCR according to patient preference and nasal anatomical characteristics. All patients received bicanalicular silicone tube intubation. Follow-up examinations were performed on postoperative day 1, week 1, at month 1, and every three months thereafter. Anatomical success was defined as patency on nasolacrimal irrigation, and functional success was defined as a postoperative Munk score of \u2264 1 (complete or near-complete resolution of epiphora). QoL was assessed using the Lacrimal Symptom Questionnaire (Lac-Q) and the Glasgow Benefit Inventory (GBI). Statistical comparisons were performed between groups. Results: A total of 69 patients (45 women, 24 men; mean age 58.99 \u00b1 14.86 years) were included, with a mean follow-up of 17.19 \u00b1 4.07 months. The highest postoperative pain scores were observed in the EX-DCR group; with no significant intergroup differences. Anatomical success rates were 92% for EX-DCR, 90.5% for EN-DCR, and 91.3% for TL-DCR. Functional success rates were 88%, 90.5%, and 82.7%, respectively, with no statistically significant difference among techniques (p &gt; 0.05). All groups showed postoperative improvement in Lac-Q and GBI scores. Numerically greater improvements were observed in the EN-DCR group, although intergroup differences were not statistically significant. Conclusions: EX-DCR achieved the numerically highest anatomical success rate, whereas EN-DCR demonstrated numerically greater improvement in patient-reported QoL outcomes. However, no statistically significant differences in anatomical success, functional success, or QoL measures were observed among the three techniques. Overall, all three procedures were effective surgical options for the treatment of NLDO.<\/jats:p>","DOI":"10.3390\/jcm15124488","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T09:25:17Z","timestamp":1781083517000},"page":"4488","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the Impact of Different Dacryocystorhinostomy Techniques on Patient Quality of Life in Lacrimal Duct Obstruction"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3454-6157","authenticated-orcid":false,"given":"\u00c7a\u011fla","family":"Hakkani \u00d6znay","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7343-8757","authenticated-orcid":false,"given":"H\u00fcseyin","family":"Findik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3050-0714","authenticated-orcid":false,"given":"Feyzahan","family":"Uzun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6523-7648","authenticated-orcid":false,"given":"Muhammet","family":"Kaim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Okutucu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metin","family":"\u00c7eliker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8184-7454","authenticated-orcid":false,"given":"Mehmet","family":"Birinci","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Shin, J.-H., Kim, Y.-D., Woo, K.I., and Korean Society of Ophthalmic Plastic and Reconstructive Surgery (KSOPRS) (2015). Impact of epiphora on vision-related quality of life. BMC Ophthalmol., 15.","DOI":"10.1186\/1471-2415-15-6"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1177\/11206721241249214","article-title":"External dacryocystorhinostomy: A critical overview of the current evidence","volume":"35","author":"Locatello","year":"2025","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.1007\/s12070-024-04925-z","article-title":"Endoscopic Dacryocystorhinostomy: A Comprehensive Review of Surgical Techniques and Clinical Outcomes","volume":"76","author":"Babu","year":"2024","journal-title":"Indian J. Otolaryngol. Head. Neck Surg."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Helmi, K.W., Abdulhamid, A.S., Alomari, M.S., Alsudais, A.S., Alqurashi, B.S., Alsharif, A., Alzahrani, A.H., Bahalaq, A.M., Qutub, M.F., and Almarzouki, H.S. (2025). Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: Systematic review and meta-analysis. BMC Ophthalmol., 25.","DOI":"10.1186\/s12886-024-03818-7"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1007\/s00417-021-05165-5","article-title":"Long-term outcomes of primary transcanalicular laser dacryocystorhinostomy","volume":"259","author":"Nowak","year":"2021","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/IJO.IJO_521_24","article-title":"Functional outcome and quality of life index after endonasal versus external dacryocystorhinostomy","volume":"73","author":"Dave","year":"2025","journal-title":"Indian J. Ophthalmol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1038\/eye.2017.120","article-title":"Assessment of patient-reported outcome and quality of life improvement following surgery for epiphora","volume":"31","author":"Sipkova","year":"2017","journal-title":"Eye"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1097\/IOP.0000000000000977","article-title":"A Systematic Review of Patient-Reported Outcomes for Surgically Amenable Epiphora","volume":"34","author":"Schulz","year":"2018","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/coa.12518","article-title":"The Glasgow Benefit Inventory: A systematic review of the use and value of an otorhinolaryngological generic patient-recorded outcome measure","volume":"41","author":"Hendry","year":"2016","journal-title":"Clin. Otolaryngol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/000348949610500601","article-title":"Measuring patient benefit from otorhinolaryngological surgery and therapy","volume":"105","author":"Robinson","year":"1996","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4193\/Rhino11.042","article-title":"Development and validation of a symptom questionnaire for recording outcomes in adult lacrimal surgery","volume":"49","author":"Mistry","year":"2011","journal-title":"Rhinology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.4103\/IJO.IJO_3334_22","article-title":"Success and complications of endoscopic laser dacryocystorhinostomy vs. external dacryocystorhinostomy: A systematic review and meta-analysis","volume":"71","author":"Panda","year":"2023","journal-title":"Indian J. Ophthalmol."},{"key":"ref_13","first-page":"184","article-title":"Endoskopik dakriosistorinostomi: Oftalmoloji ekibinin ge\u00e7 d\u00f6nem sonu\u00e7lar\u0131","volume":"16","author":"Konuk","year":"2009","journal-title":"MN Oftalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.5152\/tao.2016.1722","article-title":"Comparison of Endoscopic and External Dacryocystorhinostomy Results and Analysis of Patients\u2019 Satisfaction","volume":"54","author":"Somuk","year":"2016","journal-title":"Turk. Arch. Otorhinolaryngol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/01676830.2025.2571443","article-title":"External versus endonasal dacryocystorhinostomy: A single-centre United Kingdom study of 512 consecutive operations","volume":"45","author":"Sultan","year":"2026","journal-title":"Orbit"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1007\/s00417-023-06089-y","article-title":"Success rate of external, endonasal, and transcanalicular laser DCR with or without silicone stent intubation for NLD obstruction: A network meta-analysis of randomized controlled trials","volume":"261","author":"Evereklioglu","year":"2023","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"517","DOI":"10.15562\/ism.v16i2.2237","article-title":"The outcomes of transcanalicular laser dacryocystorhinostomy versus external dacryocystorhinostomy in nasolacrimal duct obstruction: A systematic review and meta-analysis","volume":"16","author":"Andrastea","year":"2025","journal-title":"Intisari Sains Medis"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13005-026-00602-4","article-title":"Exploring patient-reported outcomes after lacrimal surgery in a large monocentric cohort: Cross-cultural adaptation of the Italian Lac-Q","volume":"22","author":"Pirola","year":"2026","journal-title":"Head. Face Med."},{"key":"ref_19","first-page":"48","article-title":"The impact of endonasal dacryocystorhinostomy (DCR), on patient health status as assessed by the Glasgow benefit inventory","volume":"47","author":"Spielmann","year":"2009","journal-title":"Rhinology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/IOP.0000000000000660","article-title":"Assessing the Outcomes of Powered Endoscopic Dacryocystorhinostomy in Adults Using the Lacrimal Symptom (Lac-Q) Questionnaire","volume":"33","author":"Ali","year":"2017","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3109\/02713683.2012.658488","article-title":"Assessment of patient satisfaction following external versus transcanalicular dacryocystorhinostomy with a diode laser and evaluation if change in quality of life after simultaneous bilateral surgery in patients with bilateral nasolacrimal duct obstruction","volume":"37","author":"Yeniad","year":"2012","journal-title":"Curr. Eye Res."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Timlin, H.M., Kang, S., Jiang, K., and Ezra, D.G. (2021). Recurrent epiphora after dacryocystorhinostomy surgery: Structural abnormalities identified with dacryocystography and long term outcomes of revision surgery: Success rates of further surgery following failed dacryocystorhinostomy surgery. BMC Ophthalmol., 21.","DOI":"10.1186\/s12886-021-01869-8"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"104","DOI":"10.4193\/Rhin08.115","article-title":"Endoscopic revision of external dacryocystorhinostomy failure","volume":"48","author":"Choussy","year":"2010","journal-title":"Rhinology"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/12\/4488\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T10:18:52Z","timestamp":1781086732000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/12\/4488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,10]]},"references-count":23,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["jcm15124488"],"URL":"https:\/\/doi.org\/10.3390\/jcm15124488","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,10]]}}}