{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T11:56:11Z","timestamp":1781265371926,"version":"3.54.1"},"reference-count":37,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The Osaka Prognostic Score (OPS) has demonstrated prognostic value in various cardiovascular settings. However, its role in predicting long-term outcomes in patients with ST-segment elevation myocardial infarction (STEMI) remains insufficiently explored. This study aimed to investigate the association between baseline OPS and one-year all-cause mortality in patients presenting with STEMI. Methods: OPS was calculated in 463 consecutive patients with STEMI at hospital admission. The primary endpoint was one-year all-cause mortality. Clinical, laboratory, echocardiographic, and angiographic variables were analyzed for each patient. Results: During one-year follow-up, patients who died exhibited significantly higher OPS values compared with survivors (1.70 \u00b1 0.89 vs. 0.38 \u00b1 0.65; p &lt; 0.001). In multivariable logistic regression analysis, lower hemoglobin levels (OR 0.780, 95% CI 0.630\u20130.967; p &lt; 0.001) and left ventricular ejection fraction (OR 0.948, 95% CI 0.902\u20130.997; p = 0.037) were associated with an increased risk of mortality whereas both the GRACE risk score (OR 2.653, 95% CI 1.345\u20133.987; p &lt; 0.001) and OPS (OR 1.536, 95% CI 1.102\u20132.234; p = 0.001) were positively associated with mortality. The combined GRACE + OPS logistic regression model demonstrated significantly better discriminative performance for predicting 1-year mortality compared with the GRACE-only model (AUC: 0.836 vs. 0.761). DeLong analysis confirmed that the addition of OPS significantly improved predictive accuracy (\u0394AUC = 0.075, 95% CI: 0.015\u20130.136; p = 0.014). Conclusions: Baseline OPS is independently associated with one-year all-cause mortality in patients with STEMI and may have potential utility in this group of patients.<\/jats:p>","DOI":"10.3390\/jcm15124561","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:49:51Z","timestamp":1781257791000},"page":"4561","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Value of the Osaka Prognostic Score for One-Year Mortality in Patients with ST-Segment Elevation Myocardial Infarction: A Retrospective Observational Cohort Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7055-8219","authenticated-orcid":false,"given":"\u00c7a\u011fatay","family":"\u00d6nal","sequence":"first","affiliation":[{"name":"Department of Cardiology, Private Gazi Hospital, 35230 \u0130zmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-3206","authenticated-orcid":false,"given":"Cennet","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bak\u0131rk\u00f6y Dr. Sadi Konuk Education and Research Hospital, 34147 \u0130stanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0450-5503","authenticated-orcid":false,"given":"Yasin","family":"Y\u00fcksel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Private Beylikd\u00fcz\u00fc Kolan Hospital, 34528 \u0130stanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burak","family":"Ay\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Private Medical Point Hospital, 35575 \u0130zmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U\u011fur","family":"Ta\u015fk\u0131n","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Private Medical Point Hospital, 35575 \u0130zmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahrettin","family":"Katkat","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cerrahpa\u015fa Medical Faculty, \u0130stanbul University, 34098 \u0130stanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e35687","DOI":"10.1097\/MD.0000000000035687","article-title":"Comprehensive review of ST-segment elevation myocardial infarction: Understanding pathophysiology, diagnostic strategies, and current treatment approaches","volume":"102","author":"Elendu","year":"2023","journal-title":"Medicine"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC Guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur. 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