{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:53:11Z","timestamp":1781765591164,"version":"3.54.5"},"reference-count":30,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: To report intraoperative safety and postoperative complications after small-incision lenticule extraction using the 2 MHz femtosecond platform (SMILE Pro; VisuMax 800) in routine practice. Methods: Retrospective consecutive case series at a single center. All planned SMILE Pro procedures were analyzed (916 eyes from 482 patients). Outcomes included completion rate, intraoperative events, postoperative complications stratified as &lt;3 and &gt;3 months, and retreatment rate. Results: Baseline age was 32.9 \u00b1 6.9 years; average preoperative refraction was \u22123.60 \u00b1 1.90\/\u22120.87 \u00b1 0.76 D (sphere\/cylinder) with best corrected visual acuity of \u22120.08 \u00b1 0.07 logMAR. Procedures were completed in 911 of 916 eyes (99.45%). Suction loss occurred in six eyes (0.66%); one was completed after redocking, four were converted (two ICL, two femtosecond LASIK) and one did not receive a second procedure. No failed lenticule separations occurred. Retreatment was performed in 14 eyes (1.54%): 11 re-LASIK, 2 ICL, and 1 cataract extraction. Early postoperative events (&lt;3 months) were mainly superficial punctate keratitis (3.51%) and dry eye (1.32%); beyond 3 months, events remained uncommon (dry eye 1.65%, photopsia\/halo\/glare 0.88%). No severe or sight-threatening complications were observed. Conclusions: SMILE Pro on the VisuMax 800 showed a high completion rate, rare intraoperative disruption, low retreatment, and rare, mostly mild postoperative events. These findings support a favorable early safety profile in routine practice; longer-term follow-up is warranted.<\/jats:p>","DOI":"10.3390\/jcm15124585","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:57:58Z","timestamp":1781513878000},"page":"4585","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Safety and Postoperative Complications After SMILE Pro: A Retrospective Case Series of 916 Eyes"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1596-3529","authenticated-orcid":false,"given":"David","family":"Beckers","sequence":"first","affiliation":[{"name":"Precise Vision Augen\u00e4rzte, Osnabr\u00fccker Strasse 233, 48429 Rheine, Germany"},{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8771-2187","authenticated-orcid":false,"given":"Florian","family":"Kretz","sequence":"additional","affiliation":[{"name":"Precise Vision Augen\u00e4rzte, Osnabr\u00fccker Strasse 233, 48429 Rheine, Germany"},{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Beckers","sequence":"additional","affiliation":[{"name":"Precise Vision Augen\u00e4rzte, Osnabr\u00fccker Strasse 233, 48429 Rheine, Germany"},{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"Saad","sequence":"additional","affiliation":[{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"},{"name":"Department of Ophthalmology, Stadtspital Zurich, 8063 Zurich, Switzerland"},{"name":"Spross Research Institute, 8063 Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Klabe","sequence":"additional","affiliation":[{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"},{"name":"Breyer Kaymak Klabe Augenchirurgie, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakan","family":"Kaymak","sequence":"additional","affiliation":[{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"},{"name":"Breyer Kaymak Klabe Augenchirurgie, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00fccella","family":"Kirca","sequence":"additional","affiliation":[{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"},{"name":"Breyer Kaymak Klabe Augenchirurgie, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9206-441X","authenticated-orcid":false,"given":"Detlev","family":"Breyer","sequence":"additional","affiliation":[{"name":"Institution for International Innovative Ophthalmic Surgery, 40212 D\u00fcsseldorf, Germany"},{"name":"Breyer Kaymak Klabe Augenchirurgie, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"459","DOI":"10.4103\/IJO.IJO_675_24","article-title":"Kerato-lenticule Extraction (KLex) surgeries\u2014Current perspectives","volume":"72","author":"Vanathi","year":"2024","journal-title":"Indian J. 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