{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T09:55:27Z","timestamp":1781517327899,"version":"3.54.1"},"reference-count":23,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective: This study aimed to compare the clinical and radiological outcomes between microscopic and unilateral biportal endoscopic (UBE) posterior cervical foraminotomy (PCF). Methods: This study included 73 patients who underwent microscopic PCF (n = 40) or UBE PCF (n = 33) for single-level cervical foraminal disc herniation or stenosis between January 2018 and December 2021. Clinical outcomes were measured using the Visual Analog Scale (VAS) and Neck Disability Index (NDI). Radiologic outcomes were evaluated with cervical range of motion (ROM) using computed tomography and flexion-extension dynamic radiography. Results: The mean follow-up period for microscopic and UBE PCF was 33.0 \u00b1 7.6 months and 29.9 \u00b1 5.9 months, respectively. The postoperative neck VAS until postoperative 2 weeks was significantly lower in the UBE PCF group than in the microscopic PCF group (p &lt; 0.05). The estimated blood loss and operative time were significantly lower in the UBE PCF group than in the microscopic PCF group, while the length of hospital stay was numerically shorter but did not reach statistical significance. The two groups had no significant difference in the NDI on the preoperative and postoperative 3 months. The recurrence occurred in 1 patient (2.5%) of the microscopic PCF group and 1 patient (3%) of the UBE PCF group. The revision surgery was performed in 2 patients (5%) of the microscopic PCF group and in 1 patient of the UBE PCF group. There were no significant differences in motion and instability between the two groups. Conclusions: Both microscopic and UBE PCF are effective and safe procedures for treating cervical radiculopathy due to cervical foraminal disc herniation or stenosis. The UBE approach may provide advantages mainly in early postoperative recovery, including lower early postoperative neck pain, while long-term clinical and radiologic outcomes appear comparable to those of microscopic PCF.<\/jats:p>","DOI":"10.3390\/jcm15124589","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:57:58Z","timestamp":1781513878000},"page":"4589","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Early Postoperative Recovery and Radiologic Outcomes Between Microscopic and Unilateral Biportal Endoscopic Posterior Cervical Foraminotomy for Cervical Radiculopathy"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2723-9316","authenticated-orcid":false,"given":"Sang Youp","family":"Han","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Spine Center, The Leon Wiltse Memorial Hospital, Suwon 16542, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6642-5285","authenticated-orcid":false,"given":"Sang Hyub","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Spine Center, The Leon Wiltse Memorial Hospital, Suwon 16542, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Won","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Spine Center, The Leon Wiltse Memorial Hospital, Suwon 16542, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choon Keun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Spine Center, The Leon Wiltse Memorial Hospital, Suwon 16542, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Seoul Central Hospital, 101, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"ref_1","first-page":"51","article-title":"Microendoscopic posterior cervical laminoforaminotomy for unilateral radiculopathy: Results of a new technique in 100 cases","volume":"95","author":"Adamson","year":"2001","journal-title":"J. Neurosurg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3171\/jns.1990.72.3.0370","article-title":"Posterolateral microdisectomy for cervical monoradiculopathy caused by posterolateral soft cervical disc sequestration","volume":"72","author":"Aldrich","year":"1990","journal-title":"J. Neurosurg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1080\/02688690042898","article-title":"Results of posterior cervical foraminotomy for treatment of cervical spondylitic radiculopathy","volume":"14","author":"Grieve","year":"2000","journal-title":"Br. J. Neurosurg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1227\/00006123-198311000-00004","article-title":"Posterior-lateral foraminotomy as an exclusive operative technique for cervical radiculopathy: A review of 846 consecutively operated cases","volume":"13","author":"Henderson","year":"1983","journal-title":"Neurosurgery"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/BF01402608","article-title":"Clinical results of the foraminotomy as described by Frykholm for the treatment of lateral cervical disc herniation","volume":"107","author":"Krupp","year":"1990","journal-title":"Acta Neurochir."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3171\/2009.1.SPINE08899","article-title":"Posterior cervical foraminotomy for the treatment of cervical radiculopathy","volume":"10","author":"Fehlings","year":"2009","journal-title":"J. Neurosurg. Spine"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1097\/00007632-199609010-00005","article-title":"Neck and shoulder pain after laminoplasty. A noticeable complication","volume":"21","author":"Hosono","year":"1996","journal-title":"Spine"},{"key":"ref_8","first-page":"230","article-title":"Cervical laminoplasty: A critical review","volume":"98","author":"Ratliff","year":"2003","journal-title":"J. Neurosurg."},{"key":"ref_9","first-page":"350","article-title":"Lateral rupture of the cervical intervertebral disc: A common cause of shoulder and arm pain","volume":"78","author":"Sampson","year":"1944","journal-title":"Surg. Gynecol. Obstet."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.3171\/2010.1.FOCUS09305","article-title":"Management of unilateral cervical radiculopathy in the military: The cost effectiveness of posterior cervical foraminotomy compared with anterior cervical discectomy and fusion","volume":"28","author":"Ponton","year":"2010","journal-title":"Neurosurg. Focus"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00002517-200102000-00004","article-title":"Comparison of biomechanical response to surgical procedures used for cervical radiculopathy: Posterior keyhole foraminotomy versus anterior foraminotomy and discectomy versus anterior discectomy with fusion","volume":"14","author":"Chen","year":"2001","journal-title":"J. Spinal Disord."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3171\/jns.1985.63.2.0278","article-title":"Cervical facetectomy and its effect on spine strength","volume":"63","author":"Raynor","year":"1985","journal-title":"J. Neurosurg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2106\/00004623-199274010-00004","article-title":"Cervical stability after foraminotomy. A biomechanical in vitro analysis","volume":"74","author":"Zdeblick","year":"1992","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Moldovan, F. (2024). Correlation between peripheric blood markers and surgical invasiveness during humeral shaft fracture osteosynthesis in young and middle-aged patients. Diagnostics, 14.","DOI":"10.3390\/diagnostics14111112"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3171\/2008.12.SPINE08576","article-title":"The posterior cervical foraminotomy in the treatment of cervical disc\/osteophyte disease: A single-surgeon experience with a minimum of 5 years\u2019 clinical and radiographic follow-up","volume":"10","author":"Jagannathan","year":"2009","journal-title":"J. Neurosurg. Spine"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1007\/s00701-017-3360-4","article-title":"Clinical and radiological results of posterior cervical foraminotomy at two or three levels: A 3-year follow-up","volume":"159","author":"Lee","year":"2017","journal-title":"Acta Neurochir."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"374","DOI":"10.3340\/jkns.2016.59.4.374","article-title":"Long-Term Outcome of Posterior Cervical Inclinatory Foraminotomy","volume":"59","author":"Heo","year":"2016","journal-title":"J. Korean Neurosurg. Soc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"539","DOI":"10.4055\/cios22050","article-title":"Percutaneous Full-Endoscopic versus Biportal Endoscopic Posterior Cervical Foraminotomy for Unilateral Cervical Foraminal Disc Disease","volume":"14","author":"Kang","year":"2022","journal-title":"Clin. Orthop. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"212","DOI":"10.14245\/ns.2142942.471","article-title":"Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes","volume":"19","author":"Kim","year":"2022","journal-title":"Neurospine"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/BSD.0000000000001507","article-title":"Unilateral Biportal Endoscopic Posterior Cervical Foraminotomy: An Outcome Comparison With the Full-endoscopic Posterior Cervical Foraminotomy","volume":"37","author":"Zhong","year":"2024","journal-title":"Clin. Spine Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1055\/s-2007-985860","article-title":"A new full-endoscopic technique for cervical posterior foraminotomy in the treatment of lateral disc herniations using 6.9-mm endoscopes: Prospective 2-year results of 87 patients","volume":"50","author":"Ruetten","year":"2007","journal-title":"Minim. Invasive Neurosurg."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Ali, M., Benfante, V., Di Raimondo, D., Laudicella, R., Tuttolomondo, A., and Comelli, A. (2024). A review of advances in molecular imaging of rheumatoid arthritis: From in vitro to clinic applications using radiolabeled targeting vectors with technetium-99m. Life, 14.","DOI":"10.3390\/life14060751"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Salvaggio, G., Midiri, F., Gagliardo, C., Salerno, S., Lupo, G., Benfante, V., Comelli, A., Re, G.L., Galia, M., and Midiri, M. (2026). Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS\/TULSA) for localized prostate cancer: A scoping review. Radiol. Medica.","DOI":"10.1007\/s11547-026-02214-z"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/12\/4589\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T09:39:47Z","timestamp":1781516387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/12\/4589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,12]]},"references-count":23,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["jcm15124589"],"URL":"https:\/\/doi.org\/10.3390\/jcm15124589","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,12]]}}}