{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T01:46:19Z","timestamp":1782783979504,"version":"3.54.5"},"reference-count":12,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Acute compartment syndrome is a surgical emergency that is most often associated with trauma. Rarely, however, it can develop without major trauma in patients receiving anticoagulation therapy. Methods: A 53-year-old woman receiving warfarin therapy presented with progressive swelling and pain in the left forearm after physical therapy. Computed tomography angiography showed preserved arterial flow. On clinical examination, pain and paralysis were present, whereas pallor and paresthesia were absent. Direct compartment pressure measurements demonstrated markedly elevated pressures in the dorsal and deep volar compartments, measuring 88 mmHg and 110 mmHg, respectively. Emergency fasciotomy was performed approximately 9 h after symptom onset. Results: Intraoperative findings showed hematoma formation and partial muscle necrosis in the deep volar compartment. After surgery, persistent bleeding required repeated hemostatic interventions and blood-product transfusion. Negative-pressure wound therapy was applied, and delayed primary closure was subsequently performed. Anticoagulation therapy was temporarily discontinued and later resumed. The patient recovered without further bleeding, wound complications, or functional impairment and was discharged in stable condition. No complications, including hematoma recurrence or infection, were observed during 6 months of follow-up. Conclusions: This case highlights a temporal association between physical therapy and acute forearm compartment syndrome in a patient receiving anticoagulation therapy. It also emphasizes that preserved peripheral pulses and intact arterial flow do not exclude the diagnosis. Early recognition and prompt surgical intervention remain essential to prevent irreversible tissue damage and optimize outcomes.<\/jats:p>","DOI":"10.3390\/jcm15135052","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:55:11Z","timestamp":1782780911000},"page":"5052","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Forearm Compartment Syndrome Following Physical Therapy in a Patient Receiving Anticoagulation Therapy: A Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"Dong Wan","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heui Ro","family":"Na","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8269-2036","authenticated-orcid":false,"given":"Seung Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4848-517X","authenticated-orcid":false,"given":"Jun Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Ha","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6766-4640","authenticated-orcid":false,"given":"Kwang Seog","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2106\/00004623-198062020-00016","article-title":"Diagnosis and management of compartmental syndromes","volume":"62","author":"Matsen","year":"1980","journal-title":"J. Bone Jt. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.2106\/00004623-197860080-00012","article-title":"Acute compartment syndromes: Diagnosis and treatment with the aid of the wick catheter","volume":"60","author":"Mubarak","year":"1978","journal-title":"J. Bone Jt. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ocl.2016.02.001","article-title":"Acute Compartment Syndrome","volume":"47","author":"Schmidt","year":"2016","journal-title":"Orthop. Clin. N. Am."},{"key":"ref_4","first-page":"1","article-title":"Acute compartment syndrome in patients on long-term anticoagulation therapy","volume":"3","author":"Mazur","year":"2018","journal-title":"J. Trauma Crit. Care"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1016\/j.jemermed.2011.09.031","article-title":"Spontaneous Compartment Syndrome of the Upper Arm in a Patient Receiving Anticoagulation Therapy","volume":"44","author":"Zimmerman","year":"2013","journal-title":"J. Emerg. Med."},{"key":"ref_6","first-page":"980940","article-title":"Acute Compartment Syndrome of the Arm after Minor Trauma in a Patient with Optimal Range of Oral Anticoagulant Therapy: A Case Report","volume":"2014","author":"Titolo","year":"2014","journal-title":"Case Rep. Orthop."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.7181\/acfs.2024.0082","article-title":"Is chitosan-based dressing more effective than gauze pressure in achieving early hemostasis after dental extractions in patients with deranged coagulation profiles?","volume":"26","author":"Rattan","year":"2025","journal-title":"Arch. Craniofacial Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"108999","DOI":"10.1016\/j.ijscr.2023.108999","article-title":"Treatment of compartment syndrome in the leg in an elderly patient with acquired hemophilia type A: A case report","volume":"112","author":"Fonseca","year":"2023","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1002\/pmrj.12771","article-title":"Hyaluronan homeostasis and its role in pain and muscle stiffness","volume":"14","author":"Amir","year":"2022","journal-title":"PMR"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"218","DOI":"10.7181\/acfs.2017.01396","article-title":"Treatment of post-traumatic hematoma and fibrosis using hyaluronidase injection","volume":"19","author":"Han","year":"2018","journal-title":"Arch. Craniofacial Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1302\/0301-620X.82B2 .9799","article-title":"Acute compartment syndrome: Who is at risk?","volume":"82","author":"McQueen","year":"2000","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Mauffrey, C., Hak, D.J., and Martin, M.P. (2019). Compartment Syndrome, Springer.","DOI":"10.1007\/978-3-030-22331-1"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/13\/5052\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T01:35:23Z","timestamp":1782783323000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/13\/5052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":12,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["jcm15135052"],"URL":"https:\/\/doi.org\/10.3390\/jcm15135052","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,29]]}}}