{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:07:30Z","timestamp":1783937250621,"version":"3.55.0"},"reference-count":30,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Post-traumatic hip osteoarthritis (PTHOA) remains the principal long-term complication after operatively treated acetabular fractures. The relative weight of patient-, injury-, and surgeon-dependent variables that drive its development is still debated. We aimed to identify independent predictors of PTHOA after open reduction and internal fixation (ORIF) of acetabular fractures. Methods: We retrospectively reviewed 130 consecutive patients who underwent ORIF for an acetabular fracture at a single tertiary trauma centre between November 2012 and January 2023 and had a minimum follow-up of 24 months. Fractures were classified using the Judet\u2013Letournel system; reduction quality was graded according to Matta. PTHOA was assessed at the latest follow-up using both the T\u00f6nnis and Kellgren\u2013Lawrence (KL) systems. Patients were stratified into three groups: no OA, mild OA (T\u00f6nnis 1\/KL 1\u20132), and advanced OA (T\u00f6nnis 2\u20133\/KL 3\u20134). Univariable and multivariable analyses identified factors independently associated with advanced OA. Results: The cohort included 106 men (81.5%) and 24 women (18.5%) with a mean age of 40.7 \u00b1 16.3 years and a mean follow-up of 3.4 years. Advanced PTHOA developed in 43 patients (33.1%); 13 (10.0%) underwent THA. On multivariable analysis, prolonged time-to-surgery (&gt;6 days; p = 0.001), associated posterior-wall\u2013transverse fracture (p = 0.038), use of the Kocher\u2013Langenbeck (K-L) approach (p = 0.038), and non-anatomic Matta reduction (p &lt; 0.001) were independently associated with advanced PTHOA. Age \u2265 40 years was significant on univariable analysis (p = 0.002) but not after adjustment. Conclusions: Reduction quality, associated posterior-wall\u2013transverse fracture morphology, surgical timing, and choice of approach are the principal determinants of PTHOA after acetabular ORIF. Early surgery and meticulous anatomic reduction should remain the cornerstones of management.<\/jats:p>","DOI":"10.3390\/jcm15145444","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T08:53:58Z","timestamp":1783932838000},"page":"5444","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Predictive Factors for Post-Traumatic Hip Osteoarthritis After Surgical Treatment of Acetabular Fractures: A Retrospective Cohort of 130 Patients"],"prefix":"10.3390","volume":"15","author":[{"given":"Onur","family":"Mercan","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology, T.C. Ministry of Health Birecik State Hospital, \u015eanl\u0131urfa 63400, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevzat","family":"G\u00f6nder","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, Gaziantep 27310, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"I\u015f\u0131k","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, Gaziantep 27310, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Letournel, E., and Judet, R. (1993). Fractures of the Acetabulum, Springer. [2nd ed.].","DOI":"10.1007\/978-3-642-75435-7"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1007\/s00402-004-0694-1","article-title":"Extensile triradiate approach in the management of combined acetabular fractures","volume":"124","author":"Kinik","year":"2004","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Tile, M., Helfet, D.L., Kellam, J.F., and Vrahas, M. (2015). Fractures of the Pelvis and Acetabulum: Principles and Methods of Management, AO Foundation. [4th ed.].","DOI":"10.1055\/b-0035-121619"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.2106\/00004623-199611000-00002","article-title":"Fractures of the acetabulum: Accuracy of reduction and clinical results in patients managed operatively within three weeks after the injury","volume":"78","author":"Matta","year":"1996","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.2106\/JBJS.K.00444","article-title":"Two to twenty-year survivorship of the hip in 810 patients with operatively treated acetabular fractures","volume":"94","author":"Tannast","year":"2012","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00003086-200302000-00026","article-title":"Displaced acetabular fractures managed operatively: Indicators of outcome","volume":"407","author":"Mears","year":"2003","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1302\/0301-620X.87B1.15605","article-title":"Operative treatment of displaced fractures of the acetabulum: A meta-analysis","volume":"87","author":"Giannoudis","year":"2005","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/00003086-199909000-00027","article-title":"Acetabular fractures: Clinical outcome of surgical treatment","volume":"366","author":"Liebergall","year":"1999","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1302\/0301-620X.88B9.17588","article-title":"Outcome of surgery for reconstruction of fractures of the acetabulum: The time dependent effect of delay","volume":"88","author":"Madhu","year":"2006","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1007\/s00264-018-4169-3","article-title":"Predictors for secondary hip osteoarthritis after acetabular fractures\u2014A pelvic registry study","volume":"43","author":"Rollmann","year":"2019","journal-title":"Int. Orthop."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.2106\/00004623-196446080-00001","article-title":"Fractures of the acetabulum: Classification and surgical approaches for open reduction","volume":"46","author":"Judet","year":"1964","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.2214\/ajr.171.5.9798851","article-title":"Acetabular fractures: Easier classification with a systematic approach","volume":"171","author":"Brandser","year":"1998","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1007\/s11999-011-1925-8","article-title":"The use of an algorithm for classifying acetabular fractures: A role for resident education?","volume":"469","author":"Ly","year":"2011","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_14","first-page":"39","article-title":"Normal values of the hip joint for the evaluation of X-rays in children and adults","volume":"119","year":"1976","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteoarthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann. Rheum. Dis."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/j.injury.2020.06.016","article-title":"Surgical management of acetabular fractures\u2014A contemporary literature review","volume":"51","author":"Kelly","year":"2020","journal-title":"Injury"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00003086-198009000-00012","article-title":"Acetabulum fractures: Classification and management","volume":"151","author":"Letournel","year":"1980","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/j.arth.2014.06.001","article-title":"Total hip arthroplasty after acetabular fracture: Incidence of complications, reoperation rates and functional outcomes. Three hundred and fifteen consecutive cases","volume":"29","author":"Makridis","year":"2014","journal-title":"J. Arthroplast."},{"key":"ref_19","first-page":"96","article-title":"Acetabular fractures in the senior population\u2014Epidemiology, mortality and treatments","volume":"5","author":"Firoozabadi","year":"2017","journal-title":"Arch. Bone Jt. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1302\/0301-620X.93B2.24056","article-title":"Outcomes of acetabular fracture fixation with ten years\u2019 follow-up","volume":"93","author":"Briffa","year":"2011","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/00005131-200310000-00005","article-title":"The \u201cGull Sign\u201d: A harbinger of failure for internal fixation of geriatric acetabular fractures","volume":"17","author":"Anglen","year":"2003","journal-title":"J. Orthop. Trauma"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.jcot.2017.01.001","article-title":"Early reduction of acetabular fractures decreases the risk of post-traumatic hip osteoarthritis","volume":"8","author":"Cahueque","year":"2017","journal-title":"J. Clin. Orthop. Trauma"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.otsr.2013.09.004","article-title":"Predictors of postoperative outcome for acetabular fractures","volume":"99","author":"Meena","year":"2013","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00003086-198604000-00030","article-title":"Fractures of the acetabulum: Early results of a prospective study","volume":"205","author":"Matta","year":"1986","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1302\/0301-620X.88B6.17342","article-title":"Determinants of functional outcome after simple and complex acetabular fractures involving the posterior wall","volume":"88","author":"Kreder","year":"2006","journal-title":"J. Bone Jt. Surg. Br."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0020-1383(93)90055-B","article-title":"Surgical treatment of acetabular posterior wall fractures","volume":"24","author":"Pantazopoulos","year":"1993","journal-title":"Injury"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0020-1383(99)00277-6","article-title":"Surgical treatment of displaced acetabular fractures\u201472 cases followed for 10 (6\u201314) years","volume":"31","author":"Chiu","year":"2000","journal-title":"Injury"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5435\/00124635-200101000-00003","article-title":"Displaced acetabular fractures: Indications for operative and nonoperative management","volume":"9","author":"Tornetta","year":"2001","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2106\/00004623-200201000-00001","article-title":"Acute total hip arthroplasty for selected displaced acetabular fractures: Two to twelve-year results","volume":"84","author":"Mears","year":"2002","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00005131-199410000-00005","article-title":"Acetabular fractures: Long-term follow-up of open reduction and internal fixation","volume":"8","author":"Wright","year":"1994","journal-title":"J. Orthop. Trauma"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/14\/5444\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T09:11:57Z","timestamp":1783933917000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/14\/5444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,11]]},"references-count":30,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["jcm15145444"],"URL":"https:\/\/doi.org\/10.3390\/jcm15145444","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,11]]}}}