{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T09:03:14Z","timestamp":1784538194014,"version":"3.55.0"},"reference-count":48,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with substantial physical and psychosocial burden. Illness acceptance is an important component of adaptation to chronic disease, yet it remains underexplored in HS. Therefore, this study aimed to assess illness acceptance in HS patients. Methods: This cross-sectional study included 123 consecutive adult HS patients. Illness acceptance was assessed using the Acceptance of Illness Scale (AIS). Disease severity was evaluated using Hurley staging and the International Hidradenitis Suppurativa Severity Score System (IHS4). Pain and itch were measured using the Numeric Rating Scale. Quality of life (QoL) was assessed with the Dermatology Life Quality Index (DLQI) and Hidradenitis Suppurativa Quality of Life (HiSQoL). Depression and anxiety were evaluated using PHQ-9, GAD-7, and HADS. Results: The mean AIS score was 31 \u00b1 8.7 points, with 14% of patients showing low and 24% moderate illness acceptance. Lower acceptance was associated with higher Hurley stage (p = 0.031). A significant negative correlation between AIS scores and IHS4 values was found (r = \u22120.26; p = 0.013). Additionally, AIS scores correlated negatively with pain (r = \u22120.22; p = 0.019) and itch (r = \u22120.23; p = 0.021). Strong negative correlations were found with QoL impairment (DLQI: r = \u22120.63; HiSQoL: r = \u22120.65; p &lt; 0.001) and psychological distress, including depression (PHQ-9: r = \u22120.55; HADS-D: r = \u22120.60) and anxiety (GAD-7: r = \u22120.50; HADS-A: r = \u22120.56; p &lt; 0.001 for all). Conclusions: Targeting illness acceptance may improve overall patient outcomes.<\/jats:p>","DOI":"10.3390\/jcm15145630","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:54:13Z","timestamp":1784534053000},"page":"5630","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Illness Acceptance in Patients with Hidradenitis Suppurativa Depends on Disease Severity and Psychosocial Parameters: An Observational Cross-Sectional Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4843-4073","authenticated-orcid":false,"given":"Marta","family":"Szepietowska","sequence":"first","affiliation":[{"name":"Department of Dermatology, Jagiellonian University Medical College, 31-008 Cracow, Poland"},{"name":"Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, 31-008 Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr K.","family":"Krajewski","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Venereology and Clinical Immunology, Faculty of Medicine, Wroclaw University of Science and Technology, 50-370 Wroc\u0142aw, Poland"},{"name":"Department of Dermato-Venereology, 4th Military Hospital, 50-981 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Przemyslaw","family":"Pacan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Institute of Medical Sciences, Rzeszow University, 35-310 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wojas-Pelc","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Jagiellonian University Medical College, 31-008 Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Matusiak","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Venereology and Clinical Immunology, Faculty of Medicine, Wroclaw University of Science and Technology, 50-370 Wroc\u0142aw, Poland"},{"name":"Department of Dermato-Venereology, 4th Military Hospital, 50-981 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej K.","family":"Jaworek","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Jagiellonian University Medical College, 31-008 Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1056\/NEJMcp1014163","article-title":"Clinical Practice. Hidradenitis Suppurativa","volume":"366","author":"Jemec","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S0140-6736(24)02475-9","article-title":"Hidradenitis Suppurativa","volume":"405","author":"Sabat","year":"2025","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41572-020-0149-1","article-title":"Hidradenitis Suppurativa","volume":"6","author":"Sabat","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1001\/jamadermatol.2025.2373","article-title":"Prevalence of Hidradenitis Suppurativa: A Meta-Analysis of Global Hidradenitis Suppurativa Atlas Studies","volume":"161","author":"Bouazzi","year":"2025","journal-title":"JAMA Dermatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000541951","article-title":"Prevalence of Hidradenitis Suppurativa in Poland","volume":"241","author":"Gurwin","year":"2025","journal-title":"Dermatology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1111\/bjd.14038","article-title":"Diagnostic Delay in Hidradenitis Suppurativa Is a Global Problem","volume":"173","author":"Saunte","year":"2015","journal-title":"Br. J. Dermatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/bjd\/ljag005","article-title":"Evaluating the Diagnostic Accuracy of a Screening Questionnaire for Detecting Hidradenitis Suppurativa: A Pooled Analysis of Accuracy Measures from the Global Hidradenitis Suppurativa Atlas (GHiSA) Study","volume":"194","author":"Bouazzi","year":"2026","journal-title":"Br. J. Dermatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/ijd.17186","article-title":"Risk of Cardiovascular Disorders in Hidradenitis Suppurativa Patients: A Large-Scale, Propensity-Matched Global Retrospective Cohort Study","volume":"63","author":"Krajewski","year":"2024","journal-title":"Int. J. Dermatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"967","DOI":"10.5114\/ada.2020.97064","article-title":"Hidradenitis Suppurativa Quality of Life (HiSQOL): Creation and Validation of the Polish Language Version","volume":"38","author":"Krajewski","year":"2021","journal-title":"Postep. Dermatol. Alergol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1007\/s13555-024-01196-y","article-title":"Profound Sexual Dysfunction among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study","volume":"14","author":"Krajewski","year":"2024","journal-title":"Dermatol. Ther."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Szepietowska, M., Krajewski, P.K., Pacan, P., Wojas-Pelc, A., Matusiak, L., and Jaworek, A.K. (2026). A Cross-Sectional Study on Relationships between Depression and Anxiety in Hidradenitis Suppurativa Patients and Disease Severity, Subjective Symptoms and Quality of Life. J. Clin. Med., 15.","DOI":"10.3390\/jcm15020700"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s13555-023-01083-y","article-title":"An Atlas of the Hidradenitis Suppurativa Transcriptome","volume":"14","author":"Szukala","year":"2024","journal-title":"Dermatol. Ther."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Knecht-Gurwin, K., Gurwin, A., Lyko, M., Drewa, T., Kielan, W., Mastalerz-Migas, A., Stojko, R., Szepietowski, J.C., and Matusiak, L. (2025). An Assessment of Clinician Knowledge of Hidradenitis Suppurativa: Insights from a Multidisciplinary Survey Study. J. Clin. Med., 14.","DOI":"10.3390\/jcm14093171"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e893","DOI":"10.1111\/jdv.20628","article-title":"Evaluation of Stigmatization in Patients with Hidradenitis Suppurativa Using the PUSH-D Score","volume":"39","author":"Fite","year":"2025","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/ijd.17569","article-title":"Stigmatization and Perceived Health Status in Patients with Hidradenitis Suppurativa: An Observational Multicenter Study in Europe","volume":"64","author":"Marron","year":"2025","journal-title":"Int. J. Dermatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.cpr.2016.04.009","article-title":"A Systematic Review of the Use of Acceptance and Commitment Therapy (ACT) in Chronic Disease and Long-Term Conditions","volume":"46","author":"Graham","year":"2016","journal-title":"Clin. Psychol. Rev."},{"key":"ref_17","first-page":"168","article-title":"Acceptance, Coping Strategies and Health Behaviors in Bipolar Disorder Patients Taking and Not Taking Lithium Carbonate","volume":"10","author":"Czajeczny","year":"2022","journal-title":"Health Psychol. Rep."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Bien, B., Krajewski, P.K., and Szepietowski, J.C. (2024). Patients\u2019 Acceptance of Psoriasis Depends on Disease Severity, Itch Intensity, and the Patients\u2019 Quality of Life: A Cross-Sectional Study. J. Clin. Med., 13.","DOI":"10.3390\/jcm13247684"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.2147\/CCID.S318603","article-title":"Illness Acceptance as the Measure of the Quality of Life in Moderate Psoriasis","volume":"14","author":"Jankowiak","year":"2021","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"530","DOI":"10.5114\/ada.2024.142580","article-title":"Illness Acceptance among Young Adults with Acne: A Cross-Sectional Study","volume":"41","author":"Bien","year":"2024","journal-title":"Postep. Dermatol. Alergol."},{"key":"ref_21","first-page":"e4588","article-title":"Illness Acceptance, Health Perception, and Hopelessness Levels in Stroke Survivors: A Cross-Sectional and Correlational Study","volume":"16","author":"Yapar","year":"2025","journal-title":"Rev. Cuid."},{"key":"ref_22","first-page":"63","article-title":"Determinants of Chronic Disease Acceptance","volume":"29","author":"Synowiec","year":"2021","journal-title":"Nurs. Probl.\/Probl. Piel\u0119g."},{"key":"ref_23","unstructured":"Roenigk, R.K., and Roenigk, H.H. (1989). Axillary Hyperhidrosis, Apocrine Bromhidrosis, Hidradenitis Suppurativa, and Familial Benign Pemphigus: Surgical Approach. Dermatologic Surgery, Marcel Dekker."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1111\/bjd.15748","article-title":"Development and Validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a Novel Dynamic Scoring System to Assess HS Severity","volume":"177","author":"Zouboulis","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/ejp.906","article-title":"Establishment of Cutpoints to Categorize the Severity of Chronic Pain Using Composite Ratings with Rasch Analysis","volume":"21","author":"Chien","year":"2017","journal-title":"Eur. J. Pain"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"502","DOI":"10.2340\/00015555-1246","article-title":"Assessment of Pruritus Intensity: Prospective Study on Validity and Reliability of the Visual Analogue Scale, Numerical Rating Scale and Verbal Rating Scale in 471 Patients with Chronic Pruritus","volume":"92","author":"Phan","year":"2012","journal-title":"Acta Derm. Venereol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1111\/jdv.17111","article-title":"Pruritus Intensity Scales across Europe: A Prospective Validation Study","volume":"35","author":"Storck","year":"2021","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0277-9536(84)90158-8","article-title":"Stress and Coping in the Explanation of Psychological Adjustment among Chronically Ill Adults","volume":"18","author":"Felton","year":"1984","journal-title":"Soc. Sci. Med."},{"key":"ref_29","unstructured":"Juczy\u0144ski, Z. (2001). Narz\u0119dzia Pomiaru w Promocji i Psychologii Zdrowia, Pracownia Test\u00f3w Psychologicznych Polskiego Towarzystwa Psychologicznego."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-2230.1994.tb01167.x","article-title":"Dermatology Life Quality Index (DLQI)\u2014A Simple Practical Measure for Routine Clinical Use","volume":"19","author":"Finlay","year":"1994","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Krajewski, P.K., Matusiak, L., von Stebut, E., Schultheis, M., Kirschner, U., Nikolakis, G., and Szepietowski, J.C. (2021). Quality-of-Life Impairment among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study of 1795 Patients. Life, 11.","DOI":"10.3390\/life11010034"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1159\/000496234","article-title":"Development of HiSQOL: A Hidradenitis Suppurativa-Specific Quality of Life Instrument","volume":"5","author":"Thorlacius","year":"2019","journal-title":"Skin Appendage Disord."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Dajpratham, P., Pukrittayakamee, P., Atsariyasing, W., Wannarit, K., Boonhong, J., and Pongpirul, K. (2020). The Validity and Reliability of the PHQ-9 in Screening for Post-Stroke Depression. BMC Psychiatry, 20.","DOI":"10.1186\/s12888-020-02699-6"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: Validity of a Brief Depression Severity Measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J. Gen. Intern. Med."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The Hospital Anxiety and Depression Scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.genhosppsych.2015.11.005","article-title":"Screening for Anxiety Disorders with the GAD-7 and GAD-2: A Systematic Review and Diagnostic Meta-Analysis","volume":"39","author":"Plummer","year":"2016","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1177\/1474515117733731","article-title":"Symptoms, Acceptance of Illness and Health-Related Quality of Life in Patients with Atrial Fibrillation","volume":"17","author":"Kaczan","year":"2018","journal-title":"Eur. J. Cardiovasc. Nurs."},{"key":"ref_39","first-page":"106","article-title":"Acceptance of Illness Scale and Its Clinical Impact","volume":"36","author":"Mazurek","year":"2014","journal-title":"Pol. Merkur. Lek."},{"key":"ref_40","first-page":"5","article-title":"Stopie\u0144 Akceptacji Choroby w Wybranych Chorobach Przewlek\u0142ych","volume":"60","author":"Niedzielski","year":"2007","journal-title":"Wiad. Lek."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/nuf.12368","article-title":"Illness Acceptance in Adolescents: A Concept Analysis","volume":"54","author":"Zheng","year":"2019","journal-title":"Nurs. Forum"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/ijd.70131","article-title":"Global Patterns of Comorbidities among Patients with Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis","volume":"65","author":"Gupta","year":"2026","journal-title":"Int. J. Dermatol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/jamadermatol.2025.2298","article-title":"Risk of New-Onset and Recurrent Depression and Anxiety among Patients with Hidradenitis Suppurativa","volume":"161","author":"Holgersen","year":"2025","journal-title":"JAMA Dermatol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/S0140-6736(08)61078-8","article-title":"Psychological Adjustment to Chronic Disease","volume":"372","author":"Geenen","year":"2008","journal-title":"Lancet"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/YCO.0b013e328014a871","article-title":"The Role of Illness Perceptions in Patients with Medical Conditions","volume":"20","author":"Petrie","year":"2007","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_46","first-page":"1485","article-title":"Pain in Hidradenitis Suppurativa: A Cross-Sectional Study of 1,795 Patients","volume":"101","author":"Krajewski","year":"2021","journal-title":"Acta Derm. Venereol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Rocholl, M., Wilke, A., Meyer, J., John, S.M., and Ludewig, M. (2023). Illness Perceptions of Patients with Occupational Skin Diseases in a Healthcare Centre for Tertiary Prevention: A Cross-Sectional Study. Int. J. Environ. Res. Public Health, 20.","DOI":"10.3390\/ijerph20095652"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2340\/actadv.v106.adv-2025-0063","article-title":"Body Modifications in Patients with Chronic Dermatoses: Associations with Body Dysmorphic Disorder and Illness Acceptance","volume":"106","author":"Putek","year":"2026","journal-title":"Acta Derm. Venereol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/14\/5630\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T08:11:48Z","timestamp":1784535108000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/14\/5630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,17]]},"references-count":48,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["jcm15145630"],"URL":"https:\/\/doi.org\/10.3390\/jcm15145630","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,17]]}}}