{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:13:09Z","timestamp":1784542389982,"version":"3.55.0"},"reference-count":38,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Trabecular micro-bypass (iStent) implantation has been shown to effectively reduce intraocular pressure (IOP) and medication burden in open-angle glaucoma. However, its efficacy in primary angle closure glaucoma (PACG) remains unclear. We conducted this study to evaluate the one-year clinical outcomes of phacoemulsification combined with goniosynechialysis and iStent implantation (Phaco-GSL-iStent) in Korean patients with PACG. Methods: This retrospective study included 65 PACG eyes that underwent Phaco-GSL-iStent with follow-up of \u226512 months. Postoperative changes in mean IOP and glaucoma medications were assessed through postoperative 12 months. Predictors of postoperative changes in IOP and glaucoma medications were also evaluated. Results: Mean IOP significantly decreased from 18.3 \u00b1 0.4 to 13.8 \u00b1 0.3 mmHg at postoperative 12 months (p &lt; 0.001). Mean number of glaucoma medications showed a statistically significant but small decrease from 2.85 \u00b1 0.15 to 2.44 \u00b1 0.13 at 12 months (p = 0.008). The 12-month cumulative qualified success rate was 86.2%. In multivariable analysis, IOP reduction at postoperative 12 months was positively associated with preoperative IOP (B = 0.707, p &lt; 0.001). IOP spikes (defined as an increase of 5 mmHg or more from the baseline) were observed in two eyes (3.1%). Conclusions: These one-year outcomes suggest that Phaco-GSL-iStent can be an effective option to lower IOP in patients with PACG. However, the reduction in glaucoma medication use was limited in this study sample.<\/jats:p>","DOI":"10.3390\/jcm15145670","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T09:32:54Z","timestamp":1784539974000},"page":"5670","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["One-Year Outcomes of Phacoemulsification Combined with Trabecular Micro-Bypass Stent Implantation and Goniosynechialysis in Primary Angle Closure Glaucoma"],"prefix":"10.3390","volume":"15","author":[{"given":"Yu-Jin","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Korea University College of Medicine, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4564-4400","authenticated-orcid":false,"given":"Chungkwon","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Korea University College of Medicine, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Jung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Korea University College of Medicine, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/bjo.86.2.238","article-title":"The definition and classification of glaucoma in prevalence surveys","volume":"86","author":"Foster","year":"2002","journal-title":"Br. 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