{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:00:00Z","timestamp":1785150000311,"version":"3.55.0"},"reference-count":28,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background: The impact of caffeinated coffee consumption on atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) remains uncertain, and clinical recommendations regarding caffeine intake are inconsistent. Methods: This retrospective observational cohort study included consecutive patients undergoing first-time PVI using a high-power short-duration technique between 2019 and 2023. Patients were stratified according to self-reported daily coffee consumption into a high-consumption group (\u22652 cups\/day) and a low-consumption group (0\u20131 cup\/day). The primary endpoint was recurrence of atrial arrhythmia within 12 months after PVI, excluding a 90-day blanking period. Multivariable logistic regression was performed to assess the association between coffee consumption and arrhythmia recurrence. Results: A total of 199 patients were included, of whom 124 (62.3%) reported high coffee consumption and 75 (37.7%) low consumption. Baseline characteristics and procedural parameters were comparable between groups. At 12 months, atrial arrhythmia recurrence occurred in 24 patients (19.4%) in the high-consumption group and 25 patients (33.3%) in the low-consumption group (p = 0.03). In multivariable analysis, higher coffee consumption was independently associated with a lower risk of recurrence (adjusted OR 0.47, 95% CI 0.23\u20130.95; p = 0.036). Conclusions: In patients undergoing first-time PVI, higher habitual consumption of caffeinated coffee was associated with a lower risk of atrial arrhythmia recurrence within one year. These findings suggest that moderate coffee consumption may be safely permitted and need not be routinely restricted in this setting. Further prospective studies are warranted to clarify whether this association is causal.<\/jats:p>","DOI":"10.3390\/jcm15155841","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T09:47:41Z","timestamp":1785145661000},"page":"5841","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Caffeinated Coffee Consumption and Atrial Arrhythmia Recurrence After Pulmonary Vein Isolation"],"prefix":"10.3390","volume":"15","author":[{"given":"Patricia","family":"H\u00e4gele","sequence":"first","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Biehler","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"L\u00f6big","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Pinchuk","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1558-0696","authenticated-orcid":false,"given":"Christian","family":"Waechter","sequence":"additional","affiliation":[{"name":"Department of Cardiology III: Adult Congenital Heart Disease and Valvular Heart Disease, University Hospital M\u00fcnster, 48149 M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6190-2145","authenticated-orcid":false,"given":"Dominik","family":"Buckert","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology, Pneumology and Internal Intensive Care Medicine, Ulm University Hospital, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1033-2119","authenticated-orcid":false,"given":"Sebastian","family":"Weyand","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Seizer","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Medical Clinic II, Ostalb Hospital Aalen, 73430 Aalen, Germany"},{"name":"Faculty of Medicine, Ulm University, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1161\/CIRCRESAHA.114.303211","article-title":"The clinical profile and pathophysiology of atrial fibrillation: Relationships among clinical features, epidemiology, and mechanisms","volume":"114","author":"Andrade","year":"2014","journal-title":"Circ. 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